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Biochemistry of Health and Disease (BHAD) Faculty

  • Jane Azizkhan-Clifford, PhD

    Professor and Chair; Associate Dean for Medical Student Research
    Department: Biochemistry & Molecular Biology
    Research Interests: Cellular response to DNA damage, regulation of gene expression, cellular proliferation and the cell cycle

  • Joris Beld, PhD

    Assistant Professor
    Department: Microbiology & Immunology
    Research Interests: Chemical biology and microbiology of secondary metabolism in various organisms

  • Karen Berkowitz, MD

    Associate Professor
    Department: Biochemistry & Molecular Biology, Obstetrics & Gynecology
    Research Interests: Mammalian germ cell development, Molecular mechanisms governing gametogenesis

  • Michael Bouchard, PhD

    Co-director, Division of Biomedical Science Programs; Professor
    Department: Biochemistry & Molecular Biology
    Research Interests: Liver cancer; hepatocyte transformation; calcium signaling; apoptosis; cell proliferation; alcohol; novel liver models; hepatitis B virology and hepatic cancer; HBx protein and hepatitis viral replication; calcium signaling and its role in cellular transformation; fatty liver disease and the gut microbiome axis

  • Irwin Chaiken, PhD

    Professor
    Department: Biochemistry & Molecular Biology
    Research Interests: Protein interactions in health and disease, structure-based antagonism of HIV-1 Env, recombinant protein/peptidomimetic/small molecule inhibitor design and mechanism of action

  • Simon Cocklin, PhD

    Associate Professor
    Department: Biochemistry & Molecular Biology
    Research Interests: Macromolecular interaction analysis, HIV-1 replication, strucuture-function relationships, ligand-receptor interactions

  • Alessandro Fatatis, MD, PhD

    Professor
    Department: Pharmacology & Physiology
    Research Interests: Cellular and molecular mechanisms regulating metastatic potential of solid tumors, studies in vitro and in animal models of neoplastic disease

  • Marilyn Jorns, PhD

    Professor
    Department: Biochemistry & Molecular Biology
    Research Interests: Use of structure-based drug design to develop a new class of drugs to treat heart failure, based on modulation of the gasotransmitter hydrogen sulfide; structure and mechanism of membrane-bound oxidoreductases

  • Patrick Loll, PhD

    Professor
    Department: Biochemistry & Molecular Biology
    Research Interests: X-ray crystallography and protein biophysics; integral membrane protein structure; antibiotic resistance; mechanism of anesthetic action; protein homeostasis

  • Alexander Mazin, PhD

    Professor
    Department: Biochemistry & Molecular Biology
    Research Interests: Mechanisms of DNA double-stranded break repair in humans and in yeast; role of homologous recombination in tumorigenesis; functions of Rad5, Rad54, and Rad51 proteins

  • Eishi Noguchi, PhD

    Associate Professor; Director, Graduate Program in Molecular & Cellular Biology & Genetics
    Department: Biochemistry & Molecular Biology
    Research Interests: Genome maintenance mechanisms relevant to the biology of cancer and aging, including DNA replication, DNA repair, DNA damage response and cell cycle checkpoints; investigating the mechanisms required for preservation of genomic integrity in response to environmental factors and toxins, including alcohol and aldehydes

  • Shae Padrick, PhD

    Assistant Professor
    Department: Biochemistry & Molecular Biology
    Research Interests: Kinetic mechanism of signal integration; X-ray crystallography and protein biophysics; cell biology; cytoskeleton dynamics; protein complexes

  • Mauricio Reginato, PhD

    Professor; Director, Graduate Program in Cancer Biology
    Department: Biochemistry & Molecular Biology
    Research Interests: Molecular mechanisms underlying breast cancer growth, survival and spread to distinct organs, in particular how cancer genes alter metabolic pathways and how these pathways may be exploited to target cancers

  • Christian Sell, PhD

    Associate Professor
    Department: Biochemistry & Molecular Biology
    Research Interests: Biology of aging; neuroendocrine networks.

  • Srinivas Somarowthu, PhD

    Assistant Professor; Interim Director, Biochemistry Program
    Department: Biochemistry & Molecular Biology
    Research Interests: Long non-coding RNAs; non-coding RNAs in viral genomes; RNA-protein complexes; molecular modeling and bioinformatics

  • Todd Strochlic, PhD, VMD

    Assistant Professor
    Department: Biochemistry & Molecular Biology
    Research Interests: Protein kinases, oncogenic signaling, breast cancer, and Drosophila oogenesis

  • Akhil Vaidya, PhD

    Professor; Director, Center for Molecular Parasitology
    Department: Microbiology & Immunology
    Research Interests: Understanding basic molecular functioning of malaria parasites with a view to developing new antimalarial drugs.

 
Teaching Faculty
 

Brad Jameson, PhD

Brad Jameson, PhD

Professor
Department:
Biochemistry & Molecular Biology


Michael White, PhD

Michael White, PhD

Professor
Department:
Biochemistry & Molecular Biology


 
Drexel Engineering/Science Faculty
 

Cameron Abrams, Biochemistry of Health and Disease Secondary Faculty

Cameron Abrams, PhD

Department: Chemical and Biological Engineering
Research Interests: Molecular simulations in biophysics and materials, HIV-1 envelope structure and function, protein-ligand binding thermodynamics and kinetics


Luis Cruz Cruz, Biochemistry of Health and Disease Secondary Faculty

Luis Cruz Cruz, PhD

Department: Physics
Research Interests: Computational studies of confinement effects on the folding of amyloidogenic proteins, spatial correlations of neurons in the brain, firing dynamics of neuronal networks, fluid flow through porous media


Frank Ferrone, Biochemistry of Health and Disease Secondary Faculty

Frank Ferrone, PhD

Department: Physics
Research Interests: Experimental and theoretical protein dynamics, kinetics of biological self-assembly, including sickle cell and Alzheimer's disease, sickle cell testing and diagnostic devices


Dionicio Martinez-Solorio, Biochemistry of Health and Disease Secondary Faculty

Dionicio Martinez-Solorio, PhD

Department: Chemistry
Research Interests: Total synthesis of complex biologically active natural products serving as inspirational platforms for the discovery and development of new reactions and synthetic methods


Aleister Saunders, PhD

Aleister Saunders, PhD

Department: Biology
Research Interests: Identifying and characterizing genes involved in pathogenesis of Alzheimer's disease (AD), aiming to identify novel therapeutic strategies to delay or prevent onset of AD


Reinhard Schweitzer-Stenner, Biochemistry of Health and Disease Secondary Faculty

Reinhard Schweitzer-Stenner, PhD

Department: Chemistry
Research Interests: Vibrational spectroscopy including IR, vibrational circular dichroism, Raman and resonance Raman spectroscopy, electronic circular dichroism spectroscopy, optical absorption spectroscopy, fluorescence spectroscopy, NMR-spectroscopy, determining Ramachandran plots of amino acid residues from vibrational and NMR spectroscopy data, global analysis of spectroscopic data, statistical thermodynamics of unfolded peptides and protein-membrane interactions


Brigita Urbanc, Biochemistry of Health and Disease Secondary Faculty

Brigita Urbanc, PhD

Department: Physics
Research Interests: Computational and experimental biophysics of protein folding and assembly, relevant to Alzheimer's and Parkinson's disease; discrete molecular dynamics of coarse-grained protein and lipid models


Jian-Min Yuan, Biochemistry of Health and Disease Secondary Faculty

Jian-Min Yuan, PhD


Department: Physics
Research Interests: Biophysics, protein folding/unfolding, protein aggregation, cellular signaling pathways, stochastic dynamics; chemical physics, reaction dyanmics, nonlinear dynamics, interaction of radiation with matter


 
Emeritus Faculty
 

Denise Ferrier, PhD

Denise Ferrier, PhD

Professor Emerita
Department:
Biochemistry & Molecular Biology
Research Interests: Development of curricula (both lecture and problem-based), and of methods to assist and assess student progress through the curricula


Gerald Soslau, PhD

Gerald Soslau, PhD

Professor Emeritus
Research Interests:
Platelet biochemistry, platelet thrombin receptors


 
Adjunct Biochemistry Faculty at Fox Chase Cancer Center
 

Sanjeevani Arora, PhD

Research Interests: Genetic studies to improve screening, early detection and treatment of cancers; mechanisms underlying genetically undefined hereditary cancers; predictive biomarkers for response to chemoradiation therapy; novel strategies to screen for individuals at high risk for cancer


Jonathan Chernoff, MD, PhD*

Research Interests: Signal transduction by small G proteins and their effectors and the role of these proteins in regulating cytoskeletal structure, tumor invasion, and metastasis; regulation of insulin signaling


Edna Cukierman, PhD

Research Interests: Isolation of primary fibroblasts from various murine and human cancers at different stages of tumorigenesis


Roland Dunbrack, PhD

Research Interests: Computational structural biology, including homology modeling, fold recognition, molecular dynamics simulations, statistical analysis of the PDB, and bioinformatics


Joan Font-Burgada, PhD

Research Interests: Cancer biology; hepatocellular carcinoma (HCC) initiation; cholangiocarcinoma (CCA) subtypes; liver regeneration


Erica Golemis, PhD

Research Interests: Understanding points of communication between the cell cycle machinery and cell shape controls, with particular reference to how these processes are simultaneously disrupted in cancer; the HEF1, HEI10, and HEI-C proteins, which function in cell cycle-cell attachment control pathways


Eileen K. Jaffe, PhD

Research Interests: Protein quaternary structure dynamics; the morpheein model of allosteric regulation; quaternary structure as a basis for understanding disease and discovering drugs


Ekaterina Koltsova, PhD

Research Interests: Uncovering immune-mediated mechanisms regulating cardiovascular disease (CVD) development, adipose tissue inflammation and cancer with particular emphasis on the role of cytokines in the regulation of intestinal microbiota, metabolites, stress hematopoiesis in the bone marrow, and anti-cancer immunity


Warren D. Kruger, PhD

Research Interests: Molecular chaperone correction of missense mutations; genetic defects of methionine metabolic enzymes and human disease


Jeffrey Peterson, PhD

Research Interests: Understanding how the Rho family of signaling proteins function in normal cells and how their signaling is altered in cancer and metastasis


Lori Rink, PhD

Research Interests: Understanding mechanisms of drug resistance in gastrointestinal stromal tumors (GIST); preclinical testing of novel agents/combinations in GIST patient derived xenografts (PDX); identification of biomarkers of response to targeted agents in soft tissue sarcomas


Yibin Yang, PhD

Research Interests: Immune signaling and regulatory pathways in lymphoid malignancies


Tim J. Yen, PhD

Research Interests: Genome stability in normal and disease states, mechanisms that ensure accurate chromosome segregation, mechanisms disrupted in cells with chromosome instability, strategies to enhance response of cancer cells to conventional chemoradiation therapies


* Physician's practice is independent of Drexel Medicine and Drexel University.

A graduate student in the Biochemistry program at Drexel University College of Medicine.