Modulation of Immune Responses by Exosomes Derived from Antigen-Presenting Cells
Shenoda BB, Ajit SK
Clin Med Insights Pathol; 9(Suppl 1):1-8. doi: 10.4137/CPath.S39925, September 14, 2016
Regulation of proinflammatory genes by the circulating microRNA hsa-miR-939
McDonald MK, Ramanathan S, Touati A, Zhou Y, Thanawala RU, Alexander GM, Sacan A, Ajit SK
Sci Rep; 6:30976. doi: 10.1038/srep30976, PMID: 27498764, Aug 8, 2016
Genome-wide redistribution of MeCP2 in dorsal root ganglia after peripheral nerve injury
Manners MT, Ertel A, Tian Y, Ajit SK
Epigenetics Chromatin; 9:23. doi: 10.1186/s13072-016-0073-5. eCollection 2016, Jun 7, 2016
Hsa-miR-34a mediated repression of corticotrophin releasing hormone receptor 1 regulates pro-opiomelanocortin expression in patients with complex regional pain syndrome
Shenoda BB, Alexander GM, Ajit SK
Journal of Translational Medicine; 14(1):64, 2016
MicroRNA-Based Biomarkers in Pain
Ramanathan S, Ajit SK
Advances in Pharmacology (San Diego, Calif.); 75:35-62, 2016
Book chapter: Epigenetics and personalized pain management
Ajit, SK
In: “Personalized Epigenetics,” Elsevier Press, Editor: Trygve Tollefsbol, Pages 389–427, 2015
MicroRNAs downregulated in neuropathic pain regulate MeCP2 and BDNF related to pain sensitivity
Manners MT, Tian Y, Zhou Z, Ajit SK
FEBS Open Bio; 5:733-40. doi: 10.1016/j.fob.2015.08.010. eCollection 2015, Aug 31, 2015
Circulating microRNA Signatures in Rodent Models of Pain
Qureshi RA, Tian Y, McDonald MK, Capasso KE, Douglas SR, Gao R, Orlova IA, Barrett JE, Ajit SK, Sacan A
Mol Neurobiol. [Epub ahead of print] Jun 18, 2015
Analgesic Response to Intravenous Ketamine Is Linked to a Circulating microRNA Signature in Female Patients With Complex Regional Pain Syndrome
Douglas SR, Shenoda BB, Qureshi RA, Sacan A, Alexander GM, Perreault M, Barrett JE, Aradillas-Lopez E, Schwartzman RJ, Ajit SK
J Pain; 16(9):814-24. doi: 10.1016/j.jpain.2015.05.008. (Epub Jun 11, 2015 ) Sep 2015
MicroRNA biology and pain
McDonald MK, Ajit SK
Prog Mol Biol Transl Sci.; 131:215-49. doi: 10.1016/bs.pmbts.2014.11.015. Review, Epub Feb 15, 2015
Effect of histone deacetylase inhibitor JNJ-26481585 in pain
Capasso KE, Manners MT, Quershi RA, Tian Y, Gao R, Hu H, Barrett JE, Sacan A, Ajit SK
J Mol Neurosci.; 55(3):570-8. doi: 10.1007/s12031-014-0391-7. (Epub Aug 2, 2014) Mar 2015
Functional significance of macrophage-derived exosomes in inflammation and pain
McDonald MK, Tian Y, Qureshi RA, Gormley M, Ertel A, Gao R, Aradillas Lopez E, Alexander GM, Sacan A, Fortina P, Ajit SK
Pain.; 155(8):1527-39. doi: 10.1016/j.pain.2014.04.029. (Epub Apr 30, 2014) Aug 2014
Purification and microRNA profiling of exosomes derived from blood and culture media
McDonald MK, Capasso KE, Ajit SK
J Vis Exp; (76):e50294. doi: 10.3791/50294, Jun 14, 2013
Circulating microRNAs as biomarkers, therapeutic targets, and signaling molecules
Ajit SK
Sensors (Basel).;12(3):3359-69. doi: 10.3390/s120303359. Review (Epub Mar 8, 2012) 2012
MicroRNA modulation in complex regional pain syndrome
Orlova IA, Alexander GM, Qureshi RA, Sacan A, Graziano A, Barrett JE, Schwartzman RJ, Ajit SK
J Transl Med.; 9:195. doi: 10.1186/1479-5876-9-195, Nov 10, 2011
Dynamic changes in the microRNA expression profile reveal multiple regulatory mechanisms in the spinal nerve ligation model of neuropathic pain
von Schack D, Agostino MJ, Murray BS, Li Y, Reddy PS, Chen J, Choe SE, Strassle BW, Li C, Bates B, Zhang L, Hu H, Kotnis S, Bingham B, Liu W, Whiteside GT, Samad TA, Kennedy JD, Ajit SK
PLoS One.;6(3):e17670. doi: 10.1371/journal.pone.0017670, Mar 14, 2011
Development of a FLIPR assay for the simultaneous identification of MrgD agonists and antagonists from a single screen
Ajit SK, Pausch MH, Kennedy JD, Kaftan EJ
J Biomed Biotechnol.; 2010. pii: 326020. doi: 10.1155/2010/326020. Epub Sep 14, 2010
The molecular basis of pain and its clinical implications in rheumatology
Bingham B, Ajit SK, Blake DR, Samad TA
Nat Clin Pract Rheumatol.; 5(1):28-37. doi: 10.1038/ncprheum0972. Review, Jan 2009
MrgD activation inhibits KCNQ/M-currents and contributes to enhanced neuronal excitability
Crozier RA, Ajit SK, Kaftan EJ, Pausch MH
J Neurosci.; 27(16):4492-6, Apr 18, 2007
RGSZ1 interacts with protein kinase C interacting protein PKCI-1 and modulates mu opioid receptor signaling
Ajit SK, Ramineni S, Edris W, Hunt RA, Hum WT, Hepler JR, Young KH
<Cell Signal.; 19(4):723-30. (Epub Oct 7, 2006) Apr 2007
Use of a murine cell line for identification of human nitric oxide synthase inhibitors
Naureckiene S, Edris W, Ajit SK, Katz AH, Sreekumar K, Rogers KE, Kennedy JD, Jones PG
J Pharmacol Toxicol Methods.; 55(3):303-13. (Epub Aug 2006) May-Jun 2007
Analysis of chimeric RGS proteins in yeast for the functional evaluation of protein domains and their potential use in drug target validation
Ajit SK, Young KH
Cell Signal.; 17(7):817-25. Epub Dec 10, 2004) Jul 2005
Enhancement of pheromone response by RGS9 and Gbeta5 in yeast
Ajit SK, Young KH
Biochem Biophys Res Commun.; 324(2):686-91, Nov 12, 2004
Yeast-based screening for inhibitors of RGS proteins
Young KH, Wang Y, Bender C, Ajit S, Ramirez F, Gilbert A, Nieuwenhuijsen BW
Methods Enzymol.; 389:277-301, 2004