Published Full-length Papers
(*corresponding author)
"The mitochondrial ribosomal protein L13 is critical for the structural and functional integrity of the mitochondrion in Plasmodium falciparum"
*Ke H, Dass S, Morrisey JM, Mather MW, Vaidya AB
J Biol Chem. pii: jbc.RA118.002552. doi: 10.1074/jbc.RA118.002552. [Epub ahead of print], April 6, 2018
"Targeting mitochondrial functions as antimalarial regime, what is next? Current Clinical Microbiology Reports"
*Ke H, Mather MW
Curr Clin Micro Rpt 4:175–191, March 2017
"Caged Garcinia Xanthones, a novel chemical scaffold with potent antimalarial activity"
*Ke H, Morrisey JM, Qu S, Chantarasriwong O, Mather MW, Theodorakis EA, Vaidya AB
Antimicrob Agents Chemother.; 61(1), Dec 27, 2016
"Genetic investigation of tricarboxylic acid metabolism during the Plasmodium falciparum life cycle"
Ke H, Lewis IA, Morrisey JM, McLean KJ, Ganesan SM, Painter HJ, Mather MW, Jacobs-Lorena M, Llinás M, Vaidya AB
Cell Rep.;11(1):164-74, Apr 7, 2015
"The heme biosynthesis pathway is essential for Plasmodium falciparum development in mosquito stage but not in blood stages"
Ke H, Sigala PA, Miura K, Morrisey JM, Mather MW, Crowley JR, Henderson JP, Goldberg DE, Long CA, Vaidya AB
J Biol Chem.; 289(50):34827-37, Dec 12, 2014
"The antimalarial activities of methylene blue and the 1,4-naphthoquinone 3-[4-(trifluoromethyl)benzyl]-menadione are not due to inhibition of the mitochondrial electron transport chain"
Ehrhardt K, Davioud-Charvet E, Ke H, Vaidya AB, Lanzer M, Deponte M
Antimicrob Agents Chemother.; 57(5):2114-20, May 2013
"Mitochondrial RNA polymerase is an essential enzyme in erythrocytic stages of Plasmodium falciparum"
Ke H, Morrisey JM, Ganesan SM, Mather MW, Vaidya AB
Mol Biochem Parasitol.; 185(1):48-51, Sep 2012
"ATP synthase complex of Plasmodium falciparum: dimeric assembly in mitochondrial membranes and resistance to genetic disruption"
Balabaskaran Nina P, Morrisey JM, Ganesan SM, Ke H, Pershing AM, Mather MW, Vaidya AB
J Biol Chem.; 286(48):41312-22, Dec 2, 2011
"A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor"
McCormack S, Bursulaya B, Ke H, Vaidya AB, Schultz PG, Winzeler EA
ACS Chem Biol.; 6(11):1214-22, Nov 18, 2011
"Variation among Plasmodium falciparum strains in their reliance on mitochondrial electron transport chain function"
Ke H, Morrisey JM, Ganesan SM, Painter HJ, Mather MW, Vaidya AB
Eukaryot Cell.; 10(8):1053-61, Aug 2011
"Yeast dihydroorotate dehydrogenase as a new selectable marker for Plasmodium falciparum transfection"
Ganesan SM, Morrisey JM, Ke H, Painter HJ, Laroiya K, Phillips MA, Rathod PK, Mather MW, Vaidya AB
Mol Biochem Parasitol.; 177(1):29-34, May 2011