See all of Dr. Reginato's publications in ResearchGate.
"O-GlcNAcylation: key regulator of glycolytic pathways"
Bacigalupa, ZA, Bhadiadra, C., and Reginato, MJ
Journal of Bioenergetics and Biomembranes 2018 Jun;50(3):189-198
"Nutrient sensor O-GlcNAcylation controls cancer lipid metabolism via SREBP-1 regulation"
Sodi VL, Bacigalupa ZA, Ferrer CM, Lee J, Gocal W, Mukherjee D, Wellen KE, Ivan M, and Reginato MJ
Oncogene. 2018 Feb 15;37(7):924-934
"Metabolite profiling reveals the glutathione biosynthetic pathway as a therapeutic target in triple negative breast cancer"
Beatty, A., Fink, LS, Singh, T, Strigun, A, Peter, E, Ferrer, CM, Nicolas, E, Cai, KQ, Moran, TP, Reginato, MJ, Rennefahrt, U, Peterson, JR
Molecular Caner Therapeutics 2018 Jan;17(1):264-275
"The addition of calcitriol or its synthetic analog EB1089 to lapatinib and neratinib treatment inhibits cell growth and promotes apoptosis in breast cancer cells."
Segovia-Mendoza, M, Díaz, L, Prado-Garcia, H, Reginato, MJ, Larrea, F and García-Becerra, R
Am J Cancer Research. Jul 1 2017;7(7):1486-1500.
"Proapoptotic protein Bim attenuates estrogen-enhanced survival in lymphangioleiomyomatosis"
Li C, Li N, Liu X, Zhang EY, Sun Y, Masuda K, Li J, Sun J, Morrison T, Li X, Chen Y, Wang J, Karim NA, Zhang Y, Blenis J, Reginato MJ, Henske EP, Yu JJ.
J. of Clinical Investigation Insight; 1(19): e86629, Nov 17, 2016
"O-GlcNAcylation regulates breast cancer metastasis via SIRT1 modulation of FoxM1 pathway"
Ferrer CM, Lu TY, Bacigalupa ZA, Katsetos CD, Sinclair DA, and Reginato, MJ
Oncogene, Jun 27 2016 [Epub ahead of print]
"O-GlcNAcylation in Cancer Biology: Linking Metabolism and Signaling"
Ferrer CM, Sodi VL and Reginato MJ
Journal of Molecular Biology, Jun 22 2016 [Epub ahead of print](add link)
"Progress towards overcoming hypoxia-induced resistance to solid tumor therapy"
Karakashev SV, and Reginato MJ
Cancer Management and Research, 12;7:253-64 Aug 2015
"Sweet Connections: O-GlcNacylation links cancer metabolism and survival"
Ferrer CM, and Reginato MJ
Molecular & Cellular Oncology, Oct 29; 2(1) 2014
"Emerging microtubule targets in glioma therapy"
Katsetos CD, Reginato MJ, Baas PW, D’Agostino L, Legido A, Tuszyn Ski JA, Draberova E, and Draber P
Seminars in Pediatric Neurology; 22(1):49-72, March 2015
"mTOR/c-MYC axis regulates O-GlcNAc transferase (OGT) expression and O-GlcNAcylation in breast cancer "
Sodi VL, Khaku S, Schwab LP, Vocadlo DJ, Seagroves TN and Reginato MJ
Molecular Cancer Research, 13(5):923-33, May 2015
Publication listed in Highlights of This Issue
"Epithelial-to-mesenchymal transition alters interstitial fluid flow-induced signaling in ERBB2-positive breast cancer cells"
Tchafa AM, Ta M, Reginato MJ and Shieh AC
Molecular Cancer Research, 13(4):755-64, Apr 2015
"Hypoxia/HIF-1a induces lapatinib resistance in ERBB2-positive breast cancer cells via regulation of DUSP2"
Karakashev SV, and Reginato MJ
Oncotarget, 6(4):1967-80, Feb 10, 2015
Book Chapter: "Cancer Metabolism: Cross Talk Between Signaling and O-GlcNAcylation"
Ferrer CM, and Reginato MJ
Cancer Genomics and Proteomics: Methods and Protocols, Methods in Molecular Biology, Vol. 1176 pp 73-88, Springer, Narendra Wajapeyee (Ed.), 2014
"O-GlcNAcylation regulates cancer metabolism and survival stress signaling via regulation of HIF-1 pathway."
Ferrer CM, Lynch TP, Sodi V, Falcone JN, Schwab L, Peacock D, Vocadlo DJ, Seagroves TN, and Reginato MJ
Molecular Cell; (54(5); 820-831, June 5, 2014
"Sticking to Sugars at the Metastatic Site: Sialyltransferase ST6GalNAc2 Acts as Breast Cancer Metastasis Suppressor"
Ferrer, CM, and Reginato, MJ
Cancer Discovery; March 4(3); 275–7, March 2014
"Activated ERBB2/HER2 licenses sensitivity to apoptosis upon endoplasmic reticulum stress through a PERK-dependent pathway"
Martin-Perez, R, Palacios, C, Yerbes, R, Cano-Gonzales, A, Iglesias-Serret, D, Gil, J, Reginato, MJ and López-Rivas A
Cancer Research; 74(6): 1766-77, March 15, 2014
"ErbB2, FoxM1, and 14-3-3ζ prime breast cancer cells for invasion in response to ionizing radiation."
Kambach DM, Sodi VL, Lelkes PI, Azizkhan-Clifford J, and Reginato MJ
Oncogene Jan 30; 33(5):589-98 (2014)
"HINCUTs in Cancer: Hypoxia-induced non-coding ultraconserved transcripts"
Ferdin J, Wu X, Nishida N Nicoloso MS, Shah NM, Devlin C, Ling H, Shimizu M, Kumar K, Cortez MA, Ferracin M, Bi Y, Yang D, Czerniack BA, Zhang W, Schmittgen TD, Voorhoeve MP, Reginato MJ, Negrini M, Davuluri RV, Kunej T, Iva, M, and Calin GA
Cell Death Differ Sep 13 2013 [Epub ahead of print]
"The oncogene HER2/neu (erbB2) requires the Hypoxia-inducible factor HIF-1 for mammary tumor growth and anoikis resistance."
Whelan KA, Schwab L, Karakashev S, Franchetti L, Johannes GJ, Seagrove, TN, and Reginato MJ
J. Biol Chem May 31; 288(22):15865-77 (2013)
"ERK2 regulated TIMP1 induces hyperproloferation of K-Ras (G12D)-transformed pancreatic ductal cells."
Botta GP, Reichert M, Reginato MJ, Heeg S, Rustgi AK and Lelkes PI
Neoplasia Apr 15 (4): 359-72 (2013)
"Control of FLIPL expression and TRAIL resistance by the extracellular signal regulated kinase (ERK)1/2 pathway in breast epithelial cells"
Yerbes R, López-Rivas A, Reginato MJ, and Palacios C
Cell Death Differ; 19:1908-16, Dec 2012
"Critical role of O-GlcNAc transferase in prostate cancer invasion, angiogenesis, and metastasis."
Lynch TP, Ferrer C, Jackson SR, Shahriari KS, Vosseller K, and Reginato MJ
J. Biol. Chem. Mar 30; 287: 11070-81 (2012)
"K-Ras activation of ERK2 in a three-dimensional model of human pancreatic cells regulates invasion via induction of matrix metalloproteinase-1"
Botta, GP, Reginato, MJ, Rustgi, AK, and Lelkes, PI
Mol. Cancer Research, Feb; 10: 183-96. (2012)
"Surviving without oxygen: Hypoxia regulation of mammary morphogenesis and anoikis"
Whelan, KA and Reginato, MJ
Cell Cycle Jul 15: 10, 2287-94 (2011)
"Cellular FLIP(L) plays a survival role and regulates morphogenesis in breast epithelial cells"
Yerbes, R, Palacios, C, Reginato, MJ, and Lopez-Rivas, A
Biochim Biophys Acta Jan: 1813, 168-78 (2011)
"O-GlcNAc transferase: A sweet new cancer target"
Lynch, TP and Reginato, MJ
Cell Cycle June 1: 10, 1712-13 (2011)
"Hypoxia suppression of Bim and Bmf blocks anoikis and luminal clearing during mammary morphogenesis"
Whelan, KA, Caldwell, SA, Shahriari, KS, Jackson, SR, Jones, L, Johannes, G and Reginato, MJ
Mol. Biol. Cell. Nov 15: 21, 3829-37 (2010)
"Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis via targeting of the oncogenic transcription factor FoxM1"
Caldwell, SA, Jackson, SR, Shahriari, KS, Lynch, TP, Sethi, G, Walker, S, Vosseller, K, and Reginato, MJ
Oncogene May 13: 29, 2831-42 (2010)
"ErbB2 requires integrin alpha5 for anoikis resistance via c-Src regulation of receptor activity in human mammary epithelial cells"
Haenssen, KK, Caldwell, SA, Shahriari, K, Jackson, R, Whelan, K, Klein-Szanto, A, and Reginato, MJ
J. of Cell Science April 15: 123, 1373-82 (2010)
"Micropatterns of matrigel for three-dimensional epithelial cultures"
Sodunke, TR, Turner, KK, Caldwell, SA, McBride, KW, Reginato, MJ and Noh, N
Biomaterials 28, 4006-16 (2007)
"Illuminating the center: mechanisms regulating lumen formation and maintenance in mammary morphogenesis"
Reginato, MJ, and Muthuswamy, SK
J Mammary Gland Biology & Neoplasia 11, 205-11 (2006)