Jasmine Peake
Mentor: Dr. Eishi Noguchi (Department of Biochemistry & Molecular Biology)

• “The p53 DNA damage response and Fanconi anemia DNA repair pathway protect against acetaldehyde-induced replication stress in esophageal keratinocytes”
  Peake JD, Horne KI, Noguchi C, Gilligan JP, Noguchi E
  Cell Cycle. 2023 Sep;22(18):2088-2096. doi: 10.1080/15384101.2023.2261740. Epub 2023 Nov 23.PMID: 37749911
• "Fanconi anemia: current insights regarding epidemiology, cancer, and DNA repair"
  Peake JD, Noguchi E
  Hum Genet. 2022 May 21. doi: 10.1007/s00439-022-02462-9. PMID: 35596788
• "FANCD2 limits acetaldehyde-induced genomic instability during DNA replication in esophageal keratinocytes"
  Peake JD, Noguchi C, Lin B, Theriault A, O'Connor M, Sheth S, Tanaka K, Nakagawa H, Noguchi E
  Mol Oncol. 2021 Jul 30. doi: 10.1002/1878-0261.13072. Online ahead of print. PMID: 34328261

Dorothy Benton
Mentor: Dr. Jonathan Chernoff (Fox Chase Cancer Center)

• “RHOA drivers take alternate routes in gastric cancer”
  Benton D, Chernoff J
  Sci Signal. 2023 Dec 19;16(816):eadk9171. doi: 10.1126/scisignal.adk9171. Epub 2023 Dec 19.PMID: 38113334
• “TRIMming away colon cancer: TRIM21-mediated ubiquitination as an activator of the Hippo tumor suppressor pathway”
  Benton D, Chernoff J
  Cell Chem Biol. 2023 Jul 20;30(7):699-701. doi: 10.1016/j.chembiol.2023.06.023. PMID: 37478825
• "A New Rho(d) Map to Diffuse Gastric Cancer"
  Benton D, Chernoff J
  Cancer Discov. Feb 2020;10(2):182-184

Emily Esquea

• “Fructose promotes liver cancer via microbial acetate-induced O-GlcNAcylation”
  Esquea EM, Young RG, Reginato MJ
  Trends Endocrinol Metab. 2024 Feb;35(2):88-90. doi: 10.1016/j.tem.2023.12.002. Epub 2023 Dec 13.PMID: 38097465
• “Selective and brain-penetrant ACSS2 inhibitors target breast cancer brain metastatic cells”
  Esquea EM, Ciraku L, Young RG, Merzy J, Talarico AN, Ahmed NN, Karuppiah M, Ramesh A, Chatoff A, Crispim CV, Rashad AA, Cocklin S, Snyder NW, Beld J, Simone NL, Reginato MJ, Dick A
  Front Pharmacol. 2024 May 16;15:1394685. doi: 10.3389/fphar.2024.1394685. eCollection 2024.PMID: 38818373

Alexa Cannon
Mentor: Dr. Jonathan Chernoff (Fox Chase Cancer Center)

• “Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints”
  Cannon AC, Budagyan K, Uribe-Alvarez C, Kurimchak AM, Araiza-Olivera D, Cai KQ, Peri S, Zhou Y, Duncan JS, Chernoff J
  Oncogene. 2024 Mar;43(10):729-743. doi: 10.1038/s41388-024-02947-z. Epub 2024 Jan 19.PMID: 38243078
• “A Facile Method to Append a Bio-ID Tag to Endogenous Mutant Kras Alleles”
  Budagyan K, Cannon AC, Chernoff J
  Methods Mol Biol. 2024;2797:351-362. doi: 10.1007/978-1-0716-3822-4_25.PMID: 38570472
• "RAC1 as a Therapeutic Target in Malignant Melanoma"
  Cannon AC, Uribe-Alvarez C, Chernoff J
  Trends Cancer. Jun 2020;6(6):478-488

John Chojnowski
Mentor: Todd Strochlic (Department of Biochemistry & Molecular Biology)

• “Copper Modulates the Catalytic Activity of Protein Kinase CK2”
  Chojnowski JE, Li R, Tsang T, Alfaran FH, Dick A, Cocklin S, Brady DC, Strochlic TI
  Front Mol Biosci. 2022 Jun 9;9:878652. doi: 10.3389/fmolb.2022.878652. eCollection 2022.PMID: 35755824

Theodore Gurrola

• “Delivering CRISPR to the HIV-1 reservoirs”
  Gurrola TE, Effah SN, Sariyer IK, Dampier W, Nonnemacher MR, Wigdahl B
  Front Microbiol. 2024 May 15;15:1393974. doi: 10.3389/fmicb.2024.1393974. eCollection 2024.PMID: 38812680

Rachel Berman

• “What's in a cure: designing a broad-spectrum HIV gene therapy”
  Berman RE, Dampier W, Nonnemacher MR, Wigdahl B
  Curr Opin HIV AIDS. 2024 May 1;19(3):150-156. doi: 10.1097/COH.0000000000000846. Epub 2024 Mar 1.PMID: 38547339

Beka Abagero

• “Detection of Duffy blood group genotypes and submicroscopic Plasmodium infections using molecular diagnostic assays in febrile malaria patients”
  Abagero BR, Rama R, Obeid A, Tolosa T, Lukas B, Teka T, Tesfaye D, Lo E, Yewhalaw D
  Malar J. 2024 Jun 20;23(1):194. doi: 10.1186/s12936-024-04875-5.PMID: 38902674

Shabnam Pirestani

• “H2-gamendazole: a new therapeutic lead for the treatment of polycystic kidney disease”
  Pirestani S, Golemis EA
  Am J Physiol Renal Physiol. 2022 Dec 1;323(6):F613-F615. doi: 10.1152/ajprenal.00225.2022. Epub 2022 Sep 15.PMID: 36108051

Carly DeAntoneo
Mentor: Dr. Siddharth Balachandran (Fox Chase Cancer Center)

• “Z-form nucleic acid-binding protein 1 (ZBP1) as a sensor of viral and cellular Z-RNAs: walking the razor's edge”
  DeAntoneo C, Herbert A, Balachandran S
  Curr Opin Immunol. 2023 Aug;83:102347. doi: 10.1016/j.coi.2023.102347. Epub 2023 Jun 3. PMID: 37276820
• "Reovirus Activated Cell Death Pathways"
  DeAntoneo C, Danthi P, Balachandran S
  Cells. 2022 May 27;11(11):1757. doi: 10.3390/cells11111757. PMID: 35681452

Anna Lilly
Mentor: Dr. Erica Golemis (Fox Chase Cancer Center)

• “Intrapancreatic fat, pancreatitis, and pancreatic cancer”
  Lilly AC, Astsaturov I, Golemis EA
  Cell Mol Life Sci. 2023 Jul 15;80(8):206. doi: 10.1007/s00018-023-04855-z

Jill Lawrence
Mentor: Dr. Michael Nonnemacher (Department of Microbiology & Immunology)

• “Roles of neuropathology-associated reactive astrocytes: a systematic review”
  Lawrence JM, Schardien K, Wigdahl B, Nonnemacher MR
  Acta Neuropathol Commun. 2023 Mar 13;11(1):42. doi: 10.1186/s40478-023-01526-9

Teddy Nguyen
Mentor: Dr. Erica Golsmis (Fox Chase Cancer Center)

• “Aurora Kinases as Therapeutic Targets in Head and Neck Cancer”
  Nguyen TT, Silva FN, Golemis EA
  Cancer J. 2022 Sep-Oct 01;28(5):387-400. doi: 10.1097/PPO.0000000000000614

Mitchell Parker
Mentor: Dr. Roland Dunbrack (Fox Chase Cancer Center)

• “Delineating the RAS Conformational Landscape”
  Parker MI, Meyer JE, Golemis EA, Dunbrack RL
  Cancer Res. 2022 Jul 5;82(13):2485-2498. doi: 10.1158/0008-5472.CAN-22-0804
• “Proliferative Signaling by ERBB Proteins and RAF/MEK/ERK Effectors in Polycystic Kidney Disease”
  Cellular Signalling (2020)

Lindsay Steele
Mentor: Dr. Boris Polyak (Department of Surgery)

• "Temporal Control over Macrophage Phenotype and the Host Response via Magnetically Actuated Scaffolds"
  Steele LA, Spiller KL, Cohen S, Rom S, Polyak B
  ACS Biomater Sci Eng. 2022 Aug 8;8(8):3526-3541. doi: 10.1021/acsbiomaterials.2c00373. PMID: 35838679

Kristopher Raghavan
Mentor: Dr. Edna Cukierman (Fox Chase Cancer Center)

• "NetrinG1+ cancer-associated fibroblasts generate unique extracellular vesicles that support the survival of pancreatic cancer cells under nutritional stress"
  Raghavan KS, Francescone R, Franco-Barraza J, Gardiner JC, Vendramini-Costa DB, Luong T, Pourmandi N, Andren A, Kurimchak A, Ogier C, Campbell PM, Duncan JS, Lyssiotis CA, Languino LR, Cukierman E
  Cancer Res Commun. 2022 Sep;2(9):1017-1036. doi: 10.1158/2767-9764.crc-21-0147. PMID: 36310768

Tara Fortino
Mentor: Dr. Michael Lane (Department of Neurobiology & Anatomy)

• "Transneuronal tracing to map connectivity in injured and transplanted spinal networks"
  Fortino TA, Randelman ML, Hall AA, Singh J, Bloom DC, Engel E, Hoh DJ, Hou S, Zholudeva LV, Lane MA
  Exp Neurol. 2022 May;351:113990. doi: 10.1016/j.expneurol.2022.113990. PMID: 35085573

Samuel Flashner
Mentor: Dr. Jane Clifford (Department of Biochemistry & Molecular Biology)

• "Transcription factor Sp1 regulates mitotic chromosome assembly and segregation"
  Flashner S, Swift M, Sowash A, Fahmy AN, Azizkhan-Clifford J
  Chromosoma. 2022 Sep;131(3):175-191. doi: 10.1007/s00412-022-00778-z. PMID: 35916925

Nima Sarfaraz
Mentor: Dr. Michael Bouchard (Department of Biochemistry & Molecular Biology)

• "The interplay of long noncoding RNAs and hepatitis B virus"
  Sarfaraz N, Somarowthu S, Bouchard MJ
  J Med Virol. 2022 Aug 9. doi: 10.1002/jmv.28058. Online ahead of print. PMID: 35946066

Lorela Ciraku
Mentor: Dr. Mauricio J. Reginato (Department of Biochemistry & Molecular Biology)

• "O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation"
  Ciraku L, Bacigalupa ZA, Ju J, Moeller RA, Le Minh G, Lee RH, Smith MD, Ferrer CM, Trefely S, Izzo LT, Doan MT, Gocal WA, D'Agostino L, Shi W, Jackson JG, Katsetos CD, Wellen KE, Snyder NW, Reginato MJ
  Oncogene. 2022 Apr;41(14):2122-2136. doi: 10.1038/s41388-022-02237-6. PMID: 35190642
• “O-GlcNAcylation regulation of cellular signaling in cancer,” published in Cell Signalling (February 2022)
• “An Ex Vivo Brain Slice Model to Study and Target Breast Cancer Brain Metastatic Tumor Growth,” published in Journal of Visualized Experiments (September 2021)

Michelle Swift
Mentor: Dr. Jane Clifford (Department of Biochemistry & Molecular Biology)

• "DNA damage-induced sumoylation of Sp1 induces its interaction with RNF4 and degradation in S phase to remove 53BP1 from DSBs and permit HR"
  Swift ML, Azizkhan-Clifford J
  DNA Repair (Amst). 2022 Mar;111:103289. doi: 10.1016/j.dnarep.2022.103289. Feb 1.PMID: 35124373
• "Sp1-dependent recruitment of the histone acetylase p300 to DSBs facilitates chromatin remodeling and recruitment of the NHEJ repair factor Ku70"
  Swift ML, Beishline K, Azizkhan-Clifford J
  DNA Repair (Amst). 2021 Sep;105:103171. doi: 10.1016/j.dnarep.2021.103171. Epub 2021 Jul 7.PMID: 34252870
• "DNA damage-induced degradation of Sp1 promotes cellular senescence"
  Swift ML, Sell C, Azizkhan-Clifford J
  Geroscience. 2021 Sep 22. doi: 10.1007/s11357-021-00456-5. Online ahead of print.PMID: 34550526
• "DSB repair pathway choice is regulated by recruitment of 53BP1 through cell cycle-dependent regulation of Sp1"
  Swift ML, Beishline K, Flashner S, Azizkhan-Clifford J
  Cell Rep. 2021;34(11):108840. doi: 10.1016/j.celrep.2021.108840

Timothy Nacarelli
Mentor: Dr. Christian Sell (Department of Pathology & Laboratory Medicine).

• "The methyltransferase enzymes KMT2D, SETD1B, and ASH1L are key mediators of both metabolic and epigenetic changes during cellular senescence"
  Nacarelli T, Azar A, Potnis M, Johannes G, Mell J, Johnson FB, Brown-Borg H, Noguchi E, Sell C
  Mol Biol Cell. 2022 May 1;33(5):ar36. doi: 10.1091/mbc.E20-08-0523. PMID: 35196069

Alexandra Guffey, MS
Mentor: Dr. Patrick Loll (Department of Biochemistry & Molecular Biology)

• “Regulation of Resistance in Vancomycin-Resistant Enterococci: The VanRS Two-Component System,” published in Microorganism (September 2021)

Jennifer Alexander
Mentor: Dr. Edna Cukierman (Fox Chase Cancer Center)

• “Palladin isoforms 3 and 4 regulate cancer-associated fibroblast pro-tumor functions in pancreatic ductal adenocarcinoma,” published in Scientific Reports (February 2021)
• "Cancer Associated Fibroblast: Mediators of Tumorigenesis," published in Matrix Biology (May 2020)

Margaret O’Connor
Mentor: Dr. Elias El Haddad (Department of Medicine)

• "A follicular regulatory Innate Lymphoid Cell population impairs interactions between germinal center Tfh and B cells"
  O'Connor MH, Muir R, Chakhtoura M, Fang M, Moysi E, Moir S, Carey AJ, Terk A, Nichols CN, Metcalf T, Petrovas C, Cameron MJ, Tardif V, Haddad EK
  Commun Biol. 2021 May 12;4(1):563. doi: 10.1038/s42003-021-02079-0. PMID: 33980982

Allison Yankey
Mentor: Dr. Srinivas Somarowthu (Department of Biochemistry & Molecular Biology)

• "Purification and Structural Characterization of the Long Noncoding RNAs"
  Yankey A, Clark SC, Owens MC, Somarowthu S
  Methods Mol Biol. 2021;2372:93-110. doi: 10.1007/978-1-0716-1697-0_10. PMID: 34417746

Kritika Hanamshet
Mentor: Dr. Alexander Mazin

• "The function of RAD52 N-terminal domain is essential for viability of BRCA-deficient cells"
  Hanamshet K, Mazin AV
  Nucleic Acids Res. 2020 Dec 16;48(22):12778-12791. doi: 10.1093/nar/gkaa1145. PMID: 33275133

Rebecca Holton
Mentor: Dr. Karen Berkowitz (Department of Biochemistry & Molecular Biology)

• "CHTF18 ensures the quantity and quality of the ovarian reserve†"
  Holton RA, Harris AM, Mukerji B, Singh T, Dia F, Berkowitz KM
  Biol Reprod. Jun 2020;103(1):24-35

Katherine Innamorati
Mentor: Dr. Garth Ehrlich (Department of Microbiology & Immunology)

• "The Bacterial Guide to Designing a Diversified Gene Portfolio"
  Innamorati KA, Earl JP, Aggarwal SD, Ehrlich GD, Hiller NL
  The Pangenome: Diversity, Dynamics and Evolution of Genomes. Tettelin H, Medini D, editors. Cham (CH): Springer; May 2020

Mihir Shetty
Mentor: Dr. Eishi Noguchi (Department of Biochemistry & Molecular Biology)

• "Maf1-dependent Transcriptional Regulation of tRNAs Prevents Genomic Instability and Is Associated With Extended Lifespan," published in Aging Cell (February 2020)