Editorial Roles
- Editor-in-chief, Genetic Testing and Molecular Biomarkers, Mary Ann Liebert, Inc Publishers
- Associate editor, BMC Ecology and Evolution, BMC Series Journals, Springer Nature Group
- Associate editor, Frontiers in Microbiology
- Associate editor, Frontiers in Genetics, Genetics of Common and Rare Diseases
- Guest editor, Frontiers in Genetics (with Drs. Regie Santoz-Cortez [GEIC] & Allen Ryan); Human Genetics Section; Topic Title – Otitis Media Genomic and Middle-ear Microbiome
- Editorial board, Microorganisms, MDPI
- Editorial board, Journal of Clinical Medicine, MDPI
- Editorial board, Genes, MDPI
Recent Selected Publications
(See all Garth Ehrlich's publications in PubMed.)
Development and Validation of Ultra-High-Fidelity Microbiome Analysis Pipeline Based on Full 16S Gene Sequencing on the PacBio
Earl JP, Krol J, Balashov SV, Bhat A, Hammond J, Sen B, Limbo J, Reed DR, Cohen N, Ehrlich GD*, and Mell, JC*
bioRxiv, doi.org/10.1101/338731 (also under revision for Microbiome)
"High Fidelity Point-of Care Diagnostic for Infected Arthroplasties: Perspective on The Accuracy of Alpha-Defensin Lateral Flow Device for Diagnosis of Periprosthetic Joint Infection. Comparison to a Gold Standard"
Ehrlich, GD and Palmer MP
J Bone Joint Surg AM. 100(1):e7, 2018
"Biobanking: Where Science and Society Meet"
Ehrlich, GD
Genetic Testing and Molecular Biomarkers. 21(3)127, 2017
"Novel Genetic Markers for Common Degenerative Orthopedic Diseases"
Ehrlich, GD
Genetic Testing and Molecular Biomarkers 21(10):577, 2017
"Next-generation molecular diagnostics provide evidence suggestive of a role for non-traditional bacterial pathogens in osteoarthritis of the knee"
Ehrlich, GD
Genetic Testing and Molecular Biomarkers. 20(12)719-720, 2016
Molecular Characterization of β-Lactamase Genes in Clinical Isolates of Carbapenem-Resistant Acinetobacter baumannii
Raible KM, Sen B, Law N, Bias T, Emery CL, Ehrlich GD, and Joshi S
Annals of Clinical Microbiology and Antimicrobials 16(1):75, 2017
Phenotypic diversity and genotypic flexibility of Burkholderia cenocepacia during long-term infection of cystic fibrosis lungs
Lee A H-Y, Flibotte S, Sinha S, Paiero A, Ehrlich RL, Balashov S, Ehrlich GD, Zlosnik JEA, Mell JC, and Nislow C
Genome Research 27:1-14, 2017
Specific amino acids in HIV-1 Vpr are significantly associated with changes in patient neurocognitive status
Dampier W, Antell GC, Aiamkitsumrit B, Nonnemacher MR, Jacobson JM, Pirrone V, Zhong W, Kercher K, Passic S, Williams JW, James A, Devlin KN, Giovannetti T, Libon DJ, Szep Z, Ehrlich GD, Wigdahl B, and Krebs FC
Journal of Neurovirology 23:113-124, 2017
Prevalence of Propionibacterium Acnes in Discs of Patients Undergoing Lumbar Microdiscectomy: A Prospective Cross-Sectional Study
Capoor MN, Ruzicka F, Machackova T, Jancalek R, Smrcka M, Schmitz JE, Hermanova MA, Sana J, Michu E, Ahmed FS, Maca K, Lipina R, Alamin T, Coscia M, Stonemetz JL, Witham T, Ehrlich GD, Gokaslan ZL, Mavrommatis K, Fischetti VA, Birkenmaier C, Slaby O
PLoS ONE Aug 18;11(8):e0161676, 2016
Comparing culture and molecular methods for the identification of microorganisms involved in necrotizing soft tissue infections
Rudkjøbing VB, Thomsen TR, Xu Y, Melton-Kreft R, Ahmed A, Eickhardt-Sørensen SR, Bjarnsholt T, Nielsen PH, Earl JP, Ehrlich GD, and Moser C
BMC Infectious Diseases
16:652-664. 2016 DOI 10.1186/s12879-016-1976-2
Complete Genome Sequence of Aggregatibacter actinomycetemcomitans Strain IDH781
May AC, Ehrlich RL, Balashov S, Ehrlich GD, Shanmugam M, Fine DH, Ramasubbu N, Mell C, Cugini C
Genome Announc. 2016 Nov 10;4(6)
Identification and Characterization of msf, a Novel Virulence Factor in Haemophilus influenzae
Kress-Bennett J, Hiller NL, Eutsey R, Powell E, Longwell MJ, Hillman T, Blackwell T, Byers B, Post JC, Hu FZ, Ehrlich GD*, and Janto, B*.
PLoS ONE 11(3):e0149891, 2016
Comparative Genomic Analyses of the Moraxella Catarrhalis Serosensitive and Seroresistant Lineages Demonstrates Their Independent Evolution
Earl JP, de Vries SPW, Ahmed A, Powell E, Schultz MP, Hermans PWM, Hill DJ, Constantinidou CI, Hu FZ, Bootsma HJ and Ehrlich GD
Genome Biology and Evolution 8(4)955-974, 2016
Shimoyama M, Smith J, de Pons J, Khampang P, Hong W, Erbe C, Ehrlich GD,Bakaletz L, and Kerschner J Next-Gen Chinchilla – Resource for an Otolaryngology Disease Model. DATABASE 2016: article ID pii: baw073, 2016.
HIV-1 genetic variation resulting in the development of new quasispecies continues to be encountered in the peripheral blood of well-suppressed patients
Dampier W, Nonnemacher MR, Mell JC, Earl J, Ehrlich GD, Pirrone V, Aiamkitsumrit B, Zhong W, Kercher K, Passic S, Williams JW, Jacobson JM, and Wigdahl B
PLoS ONE 11(5):e015538, 2016
The Use of PCR/Electron Spray Ionization-Time-of-Flight-Mass Spectrometry (PCR/ESI-TOF-MS) to Detect Bacterial and Fungal Colonization in Healthy Military Service Members
Vetor R, Murray CK, Mende K, Melton-Kreft R, Akers KA, Wenke J, Spirk T, Guymon C, Zera W, Beckius ML, Rini E, Ehrlich GD*,and Vento T*
BMC Infectious Diseases 16:338, 2016
Synovial fluid analysis using PCR-ESI-TOF-MS for detection of bacterial and fungal pathogens in native knee arthritis
Palmer MP, Hu FZ, Nistico L, Melton-Kreft R HK, Altman GT, Altman DT, Sotereanos NG, Costerton WJ, *DeMeo PJ and *Ehrlich GD
Genetic Testing and Molecular Biomarkers 20(12):721-731, 2016
Search for Microorganisms in Men with Urologic Chronic Pelvic Pain Syndrome: A Culture-Independent Analysis in the MAPP Research Network
Nickel JC, Stephens A, Landis R, Mullins C, Melton-Kreft R, and Ehrlich GD**, and the MAPP Research Network
J Urol. 194:127-135, 2015
The DpnIII Streptococcus pneumoniae restriction modification system is implicated in modulating genome plasticity and evolution among the PMEN
Eutsey RA., Powell E, Dordel J, Earl J, Clark T, Korlach J, Ehrlich GD*, and Hiller NL*
mBio. 16;6(3). pii: e00173-1, 2015
Diagnosis of periprosthetic joint infection
Zmistowski B, Della Valle C, Bauer TW, Malizos KN, Alavi A, Bedair H, Booth RE, Choong P, Deirmengian C, Ehrlich GD, Gambir A, Huang R, Kissin Y, Kobayashi H, Kobayashi N, Krenn V, Lorenzo D, Marston SB, Meermans G, Perez J, Ploegmakers JJ, Rosenberg A, Simpendorfer C, Thomas P, Tohtz S, Villafuerte JA, Wahl P, Wagenaar FC, Witzo E
J Arthroplasty. Feb;29 (2 Suppl):77-83, 2014
The Tsk2/+ mouse fibrotic phenotype is due to a gain-of-function mutation in the PIIINP segment of the Col3a1 gene
Long KB, Li Z, Burgwin CM, Choe SG, Martynanov V, Sassi-Gaha S, Earl J, Eutsey R, Ahmed A, Ehrlich GD, Artlett CM., Whitfield ML., Blankenhorn EP
J. Invest Derm. 36:9 2014. Oct 20. doi: 10.1038/jid.2014.455
The microbiome of chronic rhinosinusitis: culture, molecular diagnostics and biofilm detection
Boase S, Foreman A, Cleland E, Tan L, Melton-Kreft R, Pant H, Hu FZ, Ehrlich GD, and Warmold PJ
BMC Infectious Diseases 13:210, 2013. doi:10.1186/1471-2334-13-210. BMC Highly accessed article
Classic Publications
Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743
Rath CM, Janto B, Earl J, Ahmed A, Hu FZ, Hiller NL, Dahlgren M, Kreft M, Yu F, Wolff JJ, Kweon HK, Christiainsen MA, Håkansson K, Williams RM, Ehrlich GD, Sherman, DH
ACS Chemical Biology 6(11):1244-56, 2011
Generation of Genic Diversity among Streptococcus pneumoniae Strains via Horizontal Gene Transfer during a Chronic Polyclonal Pediatric Infection
Hiller NL, Ahmed A, Powell E, Eutsey RE, Earl J, Martin D, Janto B, Hogg JS, Boissy R, Barbadora K, Post JC, Hu FZ, and Ehrlich GD
PLoS Pathogens 6(9): e1001108, 2010
The Distributed Genome Hypothesis as a Rubric for Understanding Evolution in situ During Chronic Infectious Processes
Ehrlich GD, Ahmed A, Earl J, Hiller NL, Costerton JW, Stoodley P, Post JC, DeMeo P, and Hu FZ
FEMS Immunology and Medical Microbiology 2010 Aug;59(3):269-79
Characterization and Modeling of the Haemophilus influenzae Core and Supra-Genome based on the Complete Genomic Sequences of Rd and 12 clinical Nontypeable16 Strains
Hogg JS, *Hu FZ, Janto B, Boissy R, Gladitz J, Swierczek N, Hayes J, Keefe R, Yu S, Post JC, and Ehrlich GD
Genome Biology. 8(6)R103, 2007
Insights into the genome of large sulfur bacteria revealed by analysis of single filaments
Mussmann M, +Hu FZ, Richter M, de Beer D, Preisler A, Jørgensen BB, Huntemann M, *Glöckner FO, Amann R, Koopman WJ, Lasken RS, Janto B, Hogg J, Stoodley P, Boissy R, Ehrlich GD
PLoS Biology Sep;5(9):e230, 2007
Comparative Genomic Analyses of Seventeen Streptococcus pneumoniae Strains: Insights into the Pneumococcal Supragenome
Hiller NL, +Janto B, Hogg JS, Boissy R, Yu S, Powell E, Keefe R, Ehrlich NE, Shen K, Hayes J, Barbadora K, Klimke W, Dernovoy D, Tatusova T, Parkhill J, Bentley SD., Post JC, Ehrlich GD**, and Hu FZ
J Bacteriol. 189(22):8186-95, 2007
Direct Detection of Bacterial Biofilms on the Middle-Ear Mucosa of Children With Chronic Otitis Media
Hall-Stoodley L, Hu FZ, Stoodley P, Nistico L, Link TR, Burrows A, Post JC, Ehrlich GD, and Kerschner KE
JAMA 296:202-211, 2006**
Bacterial Plurality as a General Mechanism Driving Persistence in Chronic Infections
Ehrlich GD, Hu FZ, Shen K, Stoodley P, Post JC,
Clinical Orthopaedics and Related Research 437:20-24, 2005
Pseudomonas aeruginosa Displays Multiple Phenotypes during Development of a Biofilm
Sauer K, Camper AK, Ehrlich GD**, Costerton JW, and Davies DG
Journal of Bacteriology 184:1140-1154, 2002
Mucosal Biofilm Formation on Middle-ear Mucosa in the Chinchilla Model of Otitis Media
Ehrlich GD, Veeh R, Wang X, Costerton JW, Hayes JD, Hu FZ, Daigle BJ, Ehrlich MD, Post JC
JAMA 287:1710-1715, 2002
Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene
Whitcomb DC, Gorry MC, Preston RA, Furey WF, Sossenheimer JJ, Ulrich CD, Martin SP, Gates LK Jr., Amann ST, Toskes PP, Liddle R, McGrath K, Uomo G, Post JC, and Ehrlich GD
Nature Genetics 14:145, 1996
Crouzon Syndrome: Mutations in two spliceoforms of FGFR2 and a common point mutation shared with Jackson-Weiss Syndrome
Gorry MC, Preston RA, White GJ, Zhang Y, Singhal VK, Losken HW, Nwokoro NA, Post JC, and Ehrlich GD
Human Molecular Genetics 4:1387-1390, 1995
A gene for Crouzon craniofacial dysostosis maps to the long arm of chromosome 10
Preston RA, Post JC, Keats BJB, Aston CE, Ferrell RE, Priest J, Nouri N, Losken HW, Morris CA, Hurtt MR, Mulvihill JJ, and Ehrlich GD**
Nature Genetics 7:149-153, 1994
Prevalence of Human T-Cell Leukemia/Lymphoma Virus Type II Infection Among High Risk Individuals: Type-Specific Identification of HTLVs by Polymerase Chain Reaction
Ehrlich GD, Glaser J, Lavigne K, Quan D, Mildvan D, Sninsky K, Papsidero L, and Poiesz BJ:
Blood 74:1658-1664, 1989
Detection of human T-cell lymphotropic virus-Type I in the spinal fluid and blood of cases of chronic progressive myelopathy and a clinical, radiological and electrophysiological profile of HTLV-I associated myelopathy
Bhagavati S, Ehrlich G, Kula R, Sninsky J, Kwok S, Udani O, and Poiesz BJ
New England Journal of Medicine 318:1141, 1988
Enzymatic amplification of HTLV-I viral sequences in peripheral blood mononuclear cells and infected tissues
Kwok S, Ehrlich G, Poiesz B, Kalish R, and Sninsky JJ
Blood 72:1117-1123, 1988