• Elected fellow, American Society for Neural Therapy & Repair, 2015
• American Association of Anatomists - Young Faculty Award, 2010
• American Association of Anatomists - Postdoctoral Travel Award, 2009
• Society for Neuroscience - Postdoctoral Award, 2008
• Neuromuscular Plasticity Symposium - Presentation Award, 2008

• Australian Neuroscience Society (ANS)
• Society for Neuroscience (SfN)
• International Neurotrauma Society
• American Association of Anatomists
• American Society for Neural Therapy and Repair (ASNTR)

Visit the Lane Lab

After completing his graduate studies and early postdoctoral work in spinal cord injury (SCI) in Australia at the University of Melbourne, Dr. Lane relocated to the University of Florida to investigate the neuroplastic potential of the injured cervical spinal cord. This research developed a particular focus on respiratory dysfunction and spontaneous recovery. In 2013, Dr. Lane moved to the Spinal Cord Research Center within Drexel University College of Medicine's Department of Neurobiology & Anatomy to continue his research into neuroplasticity following cervical SCI. Employing a range of electrophysiological, behavioral and neuroanatomical methods, the present goal of his research team is to 1) better define the extent of functional and anatomical plasticity at spinal and supraspinal levels and 2) develop and test therapeutic strategies to enhance spontaneous neuroplasticity and lasting functional recovery. Among those therapeutic approaches being tested are intraspinal cell transplantation and rehabilitative strategies.

Current Funding

Title: "Optimizing functional recovery following cervical SCI"
Agency: National Institute of Health, NINDS (R01 NS081112)
Project Dates: 2012-2016
Role on project: Principal Investigator

• Stem Cell Derived Nerve Cells Improve Breathing in Rats with Spinal Cord Injuries
  MedGadget (June 7, 2018)
• Breathing Paralysis Improved through Transplantation of Lab-Grown Neurons
  Genetic Engineering & Biotechnology News (June 7, 2018)
• Lab-Grown Neurons Improve Breathing in Rats After Spinal Cord Injury
  (June 6, 2018)
• Episode 17: An Interview with Dr. Michael Lane
  SCI Curecast (December 29, 2017)
• V2a Cells: Searching for Optimal Therapies
  Christopher & Dana Reeve Foundation Blog (June 20, 2017)
• Quick Take: Improving Life for People With Spinal Cord Injuries
  Drexel News Blog (December 7, 2016)
• Breakfast with Ryk Goddard
  ABC Radio (Australia) (December 1, 2016)
• We're One Step Closer to Reversing Paralysis
  Tonic (November 17, 2016)

Recent Publications

"Enhancing neural activity to drive respiratory plasticity following cervical spinal cord injury"
Hormigo KM, Zholudeva LV, Spruance VM, Marchenko V, Pascale M-P, Vinit S, Giszter S, Bezdudnaya T, Lane MA
Experimental Neurology – Early Online (2016)

"Forelimb muscle plasticity following unilateral cervical spinal cord injury"
Gonzalez-Rothi EJ, Armstrong GT, Cerreta AJ, Fitzpatrick GM, Reier PJ, Lane MA, Judge AR, Fuller DD
Muscle Nerve, 53(3): 475-478 (2016)

"Spinal Interneurons and forelimb neuroplasticity following incomplete, high cervical spinal cord injury in adult rats"
Gonzalez-Rothi EJ, Rombola AM, Rousseau CA, Mercier LM, Fitzpatrick GM, Reier PJ, Fuller DD, Lane MA 
Journal of Neurotrauma, 32(12): 893-907 (2015)

"Diaphragmatic motor response evoked by transcranial magnetic stimulation in the rat"
Vinit S, Keomani E, Deramaudt T, Spruance VM, Bezdudnaya TG, Lane MA, Bonay M, Petitjean M
PLOS One, 9(11):e113251(2014)

"Intraspinal transplantation and modulation of donor neuron electrophysiological activity"
Lee K-Z, Lane MA, Dougherty BJ, Mercier LM, Sandhu MS, Sanchez JC, Reier PJ, Fuller DD
Experimental Neurology, 251C: 47-57 (2013)

"Phrenic motoneuron discharge patterns following chronic cervical spinal cord injury"
Lee K-Z, Dougherty BJ, Sandhu MS, Lane MA, Reier PJ, Fuller DD
Experimental Neurology, 249: 20-32 (2013)

"Respiration following spinal cord injury: evidence for human neuroplasticity"
Hoh DJ, Mercier LM, Hussey S, Lane MA
Respiratory Physiology and Neurobiology, 189(2): 450-464 - Invited Review (2013)

"Recovery of inspiratory intercostal muscle activity following high cervical hemisection"
Dougherty BJ, Lee KZ, Gonzalez-Rothi EJ, Lane MA, Reier PJ, Fuller DD
Respiratory Physiology and Neurobiology, 183(3): 186-192 (2012)

"Retrograde gene delivery to hypoglossal motoneurons using AAV9"
ElMallah MK, Falk DJ, Lane MA, Lee KZ, Shafi NI, Reier PJ, Byrne BJ, Fuller DD
Human Gene Therapy Methods, 23(2): 148-156 (2012)

"Respiratory function following bilateral mid-cervical contusion injury in the adult rat"
Lane MA, Lee KZ, Salazar K, O'Steen BE, Fuller DD, Reier PJ
Experimental Neurology, 235(1): 197-210 - Special Issue on Spinal Cord Plasticity (2012)
Invited Original Research Publication

"Contribution of the spontaneous crossed-phrenic phenomenon to inspiratory tidal volume"
Dougherty BJ, Lee KZ, Lane MA, Reier PJ, Fuller DD
Journal of Applied Physiology, 112(1): 96-105 (2011)

"Spinal respiratory motoneuron anatomy"
Lane MA
Respiratory Physiology and Neurobiology, 179: 3-13 - Invited Review (2011)

"Hypoglossal neuropathology and respiratory activity in Pompe mice"
Lee KZ, Qiu K, Falk DJ, Sandhu MS, Lane MA, Reier PJ, Byrne BJ, Fuller DD
Frontiers in Respiratory Physiology, 2:31 - Invited Review (2011)

Book Chapters - Peer Reviewed

"Axonal Degeneration and Regeneration in the Peripheral and Central Nervous Systems"
Reier PJ, Zholudeva LV, Lane MA
In: Conn PM (Ed). Conn's Translational Neuroscience. Elsevier Inc. Chapter 25 (2016)

"Spinal Cord: Repair and Rehabilitation"
Reier PJ, Hoh DJ, Mitchell G, Behrman AL, Howland DR and Lane MA
In: Encyclopedia of Life Sciences, John Wiley & Sons, U.K. (2016)

"Translational spinal cord injury research: Preclinical guidelines and challenges"
Reier PJ, Lane MA, Hall ED, Teng YD, Howland DR
In: Handbook of Clinical Neurology, Verhaagen J, McDonald JW (Eds). Amsterdam, Elsevier. 109: pp. 411-433 (2012)

"Spinal Cord: Repair and Rehabilitation"
Reier PJ, Behrman AL, Lane MA and Howland DR
In: Encyclopedia of Life Sciences. John Wiley & Sons, UK (2009)

"Degeneration, Regeneration and Plasticity in the Nervous System"
Reier PJ and Lane MA
In: Neuroscience in Medicine. 3rd Edition, Conn PM (Ed). Humana Press. Chapter 31, pp. 691-727 (2008)