Pharmacology examines and characterizes the action of drugs in humans and animals. It emphasizes the therapeutic responses of drugs, their mechanisms of action, the fate of drugs in the body, potential adverse reactions, and drug-drug interactions. Physiology considers processes that control and regulate the functioning of systems within an intact organism.
Basic physiological processes underlie all fields in biomedical science. Understanding and exploiting the specific actions of drugs can also furnish a way to probe physiological and biochemical processes in both normal and pathological circumstances. Research in pharmacology and physiology provides challenging and exciting opportunities for graduate study.
The Pharmacology & Physiology graduate students held a potluck to celebrate the return to the lab this summer.
Congratulations to Jason Wickman (mentored by Seena Ajit), winner of the Dean’s Travel Award. The Dean’s Travel Award is meant to partially defray the cost of attending a scientific meeting at which a graduate student is making a presentation, or is related to the student’s graduate study.
Katelyn Reeb won second prize for her poster presentation at the annual meeting of the Philadelphia chapter of the Society for Neuroscience (PCSFN).
Congratulations to Katelyn Reeb (mentored by Andreia Mortensen) for being awarded the PhRMA Foundation pre-doctoral fellowship (phrmafoundation.org/awards/past-award-recipients/2023-award-recipients) on her project entitled "Positive Allosteric Modulation of EAAT2 for the Treatment of Neurological Disorders."
Congratulations to Katelyn Reeb (mentored by Andreia Mortensen) and Neha Mohan (mentored by Liang Oscar Qiang), winners of the Dean’s Travel Award. The Dean’s Travel Award is meant to partially defray the cost of attending a scientific meeting at which a graduate student is making a presentation, or is related to the student’s graduate study.
"Responsible Genes for Neuronal Migration in the Chromosome 17p13.3: Beyond Pafah1b1(Lis1), Crk and Ywhae(14-3-3ε)"
Xiaonan Liu, Sarah A. Bennison, Lozen Robinson, Kazuhito Toyo-Oka
Brain Sci. 2022, 12, 56
"Mechanisms of neuronal dysfunction in HIV-associated neurocognitive disorders"
Irollo E, Luchetta J, Ho C, Nash B, Meucci O
Cell Mol Life Sci. 2021 May;78(9):4283-4303
"Human mini brains and spinal cords in a dish: Modeling strategies, current challenges, and prospective advances"
Kofman, S., Mohan, N., Sun, X., Ibric, L., Piermarini, E., Qiang, L.
Journal of tissue engineering, 13, 20417314221113391. (2022)
"Double life: How GRK2 and β-arrestin signaling participate in diseases"
Zhai R, Snyder J, Montgomery S, Sato PY
Cell Signal. 2022 Jun;94:110333
"Myocardial GRK2 Reduces Fatty Acid Metabolism and β-Adrenergic Receptor-Mediated Mitochondrial Responses"
Zhai R, Varner EL, Rao A, Karhadkar S, Di Carlo A, Snyder NW, Sato PY
Int J Mol Sci. 2022 Mar 3;23(5):2777
"Subsets of cancer cells expressing CX3CR1 are endowed with metastasis-initiating properties and resistance to chemotherapy"
DiNatale, A., Kaur, R., Qian, C., Zhang, J., Marchioli, M., Ipe, D., Castelli, M., McNair, C. M., Kumar, G., Meucci, O., Fatatis, A.
Oncogene, 41(9), 1337–1351. (2022)
"Co-receptor signaling in the pathogenesis of neuroHIV"
Nickoloff-Bybel EA, Festa L, Meucci O, Gaskill PJ
Retrovirology. 2021 Aug 24;18(1):24
"Circulating microRNAs from the mouse tibia fracture model reflect the signature from patients with complex regional pain syndrome"
Wickman JR, Luo X, Li W, Jean-Toussaint R, Sahbaie P, Sacan A, Clark JD, Ajit SK
Pain Rep. 2021 Aug 24;6(3):e950
"Therapeutic Strategies for Mutant SPAST-Based Hereditary Spastic Paraplegia"
Mohan, N., Qiang, L., Morfini, G., Baas, P. W.
Brain sciences, 11(8), 1081. (2021)