Students & Alumni
Recent Publications
Shabnam Pirestani
Mentor: Erica Golemis, PhD (Fox Chase Cancer Center)
Kalisse Horne upload/overwrite larger photo
Mentor: Eishi Noguchi, PhD (Department of Biochemistry & Molecular Biology)
Teddy Nguyen
Mentor: Erica Golemis, PhD (Fox Chase Cancer Center)
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“NN-01-195, a Novel Conjugate of HSP90 and AURKA Inhibitors, Effectively Targets Solid Tumors”
Nguyen TT, Nandwana NK, Srikanth YVV, Bagnyukova T, Chkhalo O, Cai KQ, Lamperelli J, Pirestani S, Mehra MK, Burtness BA, Borghaei H, Akunuri R, Cassel J, Lu L, Salvino JM, Golemis EA.
Mol Cancer Ther. 2026 Aug 4;25(8):1231-1245. doi: 10.1158/1535-7163.MCT-25-0857.PMID: 41576363
- “Aurora Kinases as Therapeutic Targets in Head and Neck Cancer”
Nguyen TT, Silva FN, Golemis EA
Cancer J. 2022 Sep-Oct 01;28(5):387-400. doi: 10.1097/PPO.0000000000000614
Flaviane Silva
Mentor: Erica Golemis, PhD (Fox Chase Cancer Center)
Riley Young
Mentor: Mauricio J. Reginato, PhD (Department of Biochemistry & Molecular Biology)
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“ACSS2 Suppresses Ferroptosis to Drive Breast Cancer Brain Metastasis”
Young RG, Esquea EM, Ciraku L, Merzy J, Ahmed NN, Talarico AN, Karuppiah M, Medori SM, Warade RP, Gocal W, Dick A, Simone NL, Reginato MJ.
Cancer Res. 2026 Jul 15;86(14):3502-3518. doi: 10.1158/0008-5472.CAN-25-3006.PMID: 42017807
Anna Lilly
Mentor: Erica Golemis, PhD (Fox Chase Cancer Center)
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“Role of SCAP in regulation of pancreatic homeostasis, pancreatitis, and tumorigenesis”
Lilly AC, Pavlov VA, Pirestani S, Chatoff A, Cai KQ, Cukierman E, Snyder NW, Astsaturov I, Golemis EA.
Oncogene. 2026 Jun;45(21):1999-2013. doi: 10.1038/s41388-026-03784-y. Epub 2026 Apr 15.PMID: 41986652
- “Intrapancreatic fat, pancreatitis, and pancreatic cancer”
Lilly AC, Astsaturov I, Golemis EA
Cell Mol Life Sci. 2023 Jul 15;80(8):206. doi: 10.1007/s00018-023-04855-z
Nima Sarfaraz
Mentor: Michael Bouchard, PhD (Department of Biochemistry & Molecular Biology)
Courtney Wallace
Mentor: Zachary Klase, PhD (Department of Pharmacology & Physiology)
Jill Lawrence
Mentor: Michael Nonnemacher, PhD (Department of Microbiology & Immunology)
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“Inflammatory microglia signals drive A1-like polarization of astrocytes even in the presence of HIV-1 Tat”
Lawrence JM, Dampier W, Mell JC, De Souza DR, Schardien K, Yeakle K, Barnett RJ, Sen B, Ahmed A, Bouchard M, Wigdahl B, Nonnemacher MR.
Mol Neurobiol. 2025 Dec 4;63(1):251. doi: 10.1007/s12035-025-05409-z.
- “Roles of neuropathology-associated reactive astrocytes: a systematic review”
Lawrence JM, Schardien K, Wigdahl B, Nonnemacher MR
Acta Neuropathol Commun. 2023 Mar 13;11(1):42. doi: 10.1186/s40478-023-01526-9
Camille Cunanan
Mentor: Edward Hartsough, PhD (Department of Pharmacology & Physiology)
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“Functions and clinical implications of the liver microenvironment in hepatic uveal melanoma metastases”
Cunanan CJ, Sanders AB, Gallant KC, Seedor RS, Hartsough EJ.
Cancer Metastasis Rev. 2025 Oct 29;44(4):80. doi: 10.1007/s10555-025-10298-8.
- “BAP1 Loss Affords Lipotoxicity Resistance in Uveal Melanoma”
Cunanan CJ, Amirfallah A, Sanders AB, Gallant KC, Cavallo MR, Homer EA, El Naggar OS, Farnan JK, Romano G, Hope JL, Jackson JG, Hartsough EJ.
Pigment Cell Melanoma Res. 2025 May;38(3):e70021. doi: 10.1111/pcmr.70021.
Chloe Azadegan
Mentor: Johnathan Whetstine, PhD (Fox Chase Cancer Center)
Shih-Chun Shen
Mentor: Alexander Muller, PhD (Lankenau Institute for Medical Research)
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“Neovascular pruning by IDO1 inhibitors can potentiate immunogenic cytotoxicity of ischemia-targeted agents to synergistically enhance anti-PD-1 responsiveness”
Shen SC, Dey S, DuHadaway JB, Sutanto-Ward E, Hampton MT, Kozlov SV, Prendergast GC, Muller AJ.
J Immunother Cancer. 2025 May 30;13(5):e011398. doi: 10.1136/jitc-2024-011398.
- “Matrigel implants embedded with IDVCs (IDO1-dependent vascularizing cells) to study inflammatory neovascularization”
Shen SC, DuHadaway JB, Mondal A, Dey S, Muller AJ.
Methods Cell Biol. 2025;196:251-270. doi: 10.1016/bs.mcb.2025.01.010.
Konstantin Budagyan
Mentor: Jonathan Chernoff, PhD (Fox Chase Cancer Center)
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“KRAS G12V mutation-selective requirement for ACSS2 in colorectal adenoma formation”
Budagyan K, Cannon AC, Chatoff A, Benton D, Kurimchak AM, Araiza-Olivera D, Gerasimova A, Snyder NW, Duncan JS, Uribe-Alvarez C, Chernoff J.
Cell Rep. 2025 Apr 22;44(4):115444. doi: 10.1016/j.celrep.2025.115444.
- “A Facile Method to Engineer Mutant Kras Alleles in an Isogenic Cell Background”
Budagyan K, Chernoff J
Methods Mol Biol. 2021;2262:323-334. doi: 10.1007/978-1-0716-1190-6_20. PMID: 33977487
Zachary Capriotti
Mentor: Zachary Klase, PhD (Department of Pharmacology & Physiology)
Jason DaCunza
Mentor: Seena Ajit, PhD (Department of Pharmacology & Physiology)
Kareen Pestana
Mentor: Eugenia Lo, PhD (Department of Microbiology & Immunology)
- “Copy Number Variations of Plasmodium vivax DBP1, EBP/DBP2, and RBP2b in Ethiopians Who Are Duffy Positive and Duffy Negative”
Pestana K, Ford A, Rama R, Abagero B, Kepple D, Tomida J, Popovici J, Yewhalaw D, Lo E
J Infect Dis. 2024 Oct 16;230(4):1004-1012. doi: 10.1093/infdis/jiae388. PMID: 39102894
Jasmine Peake
Mentor: Eishi Noguchi, PhD (Department of Biochemistry & Molecular Biology)
- “The p53 DNA damage response and Fanconi anemia DNA repair pathway protect against acetaldehyde-induced replication stress in esophageal keratinocytes”
Peake JD, Horne KI, Noguchi C, Gilligan JP, Noguchi E
Cell Cycle. 2023 Sep;22(18):2088-2096. doi: 10.1080/15384101.2023.2261740. Epub 2023 Nov 23.PMID: 37749911
- “Fanconi anemia: current insights regarding epidemiology, cancer, and DNA repair”
Peake JD, Noguchi E
Hum Genet. 2022 May 21. doi: 10.1007/s00439-022-02462-9. PMID: 35596788
- “FANCD2 limits acetaldehyde-induced genomic instability during DNA replication in esophageal keratinocytes”
Peake JD, Noguchi C, Lin B, Theriault A, O'Connor M, Sheth S, Tanaka K, Nakagawa H, Noguchi E
Mol Oncol. 2021 Jul 30. doi: 10.1002/1878-0261.13072. Online ahead of print. PMID: 34328261
Emily Esquea
- “Fructose promotes liver cancer via microbial acetate-induced O-GlcNAcylation”
Esquea EM, Young RG, Reginato MJ
Trends Endocrinol Metab. 2024 Feb;35(2):88-90. doi: 10.1016/j.tem.2023.12.002. Epub 2023 Dec 13.PMID: 38097465
- “Selective and brain-penetrant ACSS2 inhibitors target breast cancer brain metastatic cells”
Esquea EM, Ciraku L, Young RG, Merzy J, Talarico AN, Ahmed NN, Karuppiah M, Ramesh A, Chatoff A, Crispim CV, Rashad AA, Cocklin S, Snyder NW, Beld J, Simone NL, Reginato MJ, Dick A
Front Pharmacol. 2024 May 16;15:1394685. doi: 10.3389/fphar.2024.1394685. eCollection 2024.PMID: 38818373
Alexa Cannon
Mentor: Jonathan Chernoff, PhD (Fox Chase Cancer Center)
- “Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints”
Cannon AC, Budagyan K, Uribe-Alvarez C, Kurimchak AM, Araiza-Olivera D, Cai KQ, Peri S, Zhou Y, Duncan JS, Chernoff J
Oncogene. 2024 Mar;43(10):729-743. doi: 10.1038/s41388-024-02947-z. Epub 2024 Jan 19.PMID: 38243078
- “A Facile Method to Append a Bio-ID Tag to Endogenous Mutant Kras Alleles”
Budagyan K, Cannon AC, Chernoff J
Methods Mol Biol. 2024;2797:351-362. doi: 10.1007/978-1-0716-3822-4_25.PMID: 38570472
- “RAC1 as a Therapeutic Target in Malignant Melanoma”
Cannon AC, Uribe-Alvarez C, Chernoff J
Trends Cancer. Jun 2020;6(6):478-488
John Chojnowski
Mentor: Todd Strochlic, VMD, PhD (Department of Biochemistry & Molecular Biology)
Theodore Gurrola
- “Delivering CRISPR to the HIV-1 reservoirs”
Gurrola TE, Effah SN, Sariyer IK, Dampier W, Nonnemacher MR, Wigdahl B
Front Microbiol. 2024 May 15;15:1393974. doi: 10.3389/fmicb.2024.1393974. eCollection 2024.PMID: 38812680
Rachel Berman
Beka Abagero
Carly DeAntoneo
Mentor: Siddharth Balachandran, PhD (Fox Chase Cancer Center)
Nicholas Duchemin
Mentor: Michael Bouchard, PhD (Department of Biochemistry & Molecular Biology)