Joshua Lequieu

Joshua Lequieu

Assistant Professor
Chemical and Biological Engineering

Joshua Lequieu

Assistant Professor
Chemical and Biological Engineering


Joshua Lequieu's research is focused on developing predictive multi-scale models of nano-structured soft matter. By combining insights from materials science and biology, his research seeks to provide a mechanistic understanding of complex molecular systems with applications ranging from energy to human health.

A central component of his research is a multi-scale strategy that bridges atomistic, coarse-grained, and field-theoretic simulations, thereby providing the ability to examine phenomena that span many length and time scales.

His current research interests are in block polymer self-assembly, nanoporous materials, and chromatin.

Degrees / Education

  • Postdoctoral Fellow, University of California - Santa Barbara, 2017 - 2019
  • PhD, Molecular Engineering, University of Chicago, 2017
  • BS, Chemical Engineering, Cornell University, 2010

Research Areas

Areas of Study

Academic Distinctions

  • 2019 Edward J. Kramer Prize in Materials, University of California -- Santa Barbara
  • 2017 William Rainey Harper Dissertation Fellowship, University of Chicago

Select Publications

  • Lequieu, J., Koeper, T., Delaney, K. T., & Fredrickson, G. H. (2020). Extreme Deflection of Phase Boundaries and Chain Bridging in A(BA′)n Miktoarm Star Polymers. Macromolecules, 53, 513–522.  
  • Morgan W. Bates*, Joshua Lequieu*, Stephanie M. Barbon, Ronald M. Lewis, Kris T. Delaney, Athina Anastasaki, Craig J Hawker, Glenn H. Fredrickson, and Christopher M. Bates. Stability of the A15 phase in diblock copolymer melts. Proc. Nat. Acad. Sci. USA., 116(27):13194--13199, 2019
    * equal contribution
  • Joshua Lequieu, Andrés Córdoba, Joshua Moller, and Juan J de Pablo. 1CPN : A coarse-grained multi-scale model of chromatin. J. Chem. Phys., 150:215102, 2019
  • Joshua Lequieu, David C. Schwartz, and Juan J. de Pablo. In silico evidence for sequence-dependent nucleosome sliding. Proc. Nat. Acad. Sci. USA., 114:E9197–E9205, 2017
  • Joshua Lequieu, Andrés Córdoba, David C. Schwartz, and Juan J. de Pablo. Tension-dependent free energies of nucleosome unwrapping. ACS Cent. Sci., 2(9):660–666, 2016