Dr. Hao Cheng is currently an Assistant Professor in the Department of Materials Science & Engineering at Drexel University, and affiliated faculty member in the School of Biomedical Engineering, Science, and Health Systems. He received his B.E. and M.S. degrees in Chemical Engineering from Tsinghua University in China, and his Ph.D. degree in Materials Science & Engineering from Northwestern University. He was a postdoctoral associate in cancer biology at Northwestern University, and Koch Institute for Integrative Cancer Research and Department of Chemical Engineering at MIT. He has published 30 papers in Journals such as PNAS, Nano Letters, ACS Nano, Advanced Materials, and Biomaterials. His current research focuses on the investigation of fundamental nanomaterial-cell interactions and the development of new biomaterials for immunotherapy.
Degrees / Education
- PhD Materials Science and Engineering, Northwestern University, 2005
- MS Chemical Engineering, Tsinghua University, 2001
- BE Chemical Engineering, Tsinghua University, 1999
Biomaterials, immunoengineering, drug delivery, nanomedicine, cell engineering
Areas of Study
- Fan Z.Y.,1 Li P.Y.,1 Deng J.J. Bady S.C., Cheng H.* Cell membrane coating for reducing nanoparticle-induced inflammatory responses to scaffold constructs. Nano Research (2018) In press. (1authors contribute equally)
- Li Y.P.1, Fan Z.Y.1, Cheng H.* Cell membrane bioconjugation and membrane-derived nanomaterials for immunotherapy. Bioconjugate Chemistry 29, 624-634 (2018) (1authors contribute equally)
- Zhou H., Fan Z.Y., Lemons P.K., Cheng H.* A facile approach to functionalize cell membrane-coated nanoparticles. Theranostics 6, 1012-1022 (2016).
- Zhou H., Fan Z.Y., Deng J.J., Lemons P.K., Arhontouslis D.C., Bowne W.B., Cheng H.* Hyaluronidase embedded in nanocarrier PEG shell for enhanced tumor penetration and highly efficient antitumor efficacy. Nano Letters 16, 3268-3277 (2016).
- Wang Q.1, Cheng H.1*, Peng H., Zhou H., Li P.Y., Langer R.* Non-genetic engineering of cells for drug delivery and cell-based therapy. Advanced Drug Delivery Reviews 91, 125-140 (2015). (1authors contribute equally)
- Fan Z.Y., Zhou H., Li P.Y., Speer J.E., Cheng H.* Structural elucidation of cell membrane-derived nanoparticles using molecular probes. Journal of Materials Chemistry B 2, 8231-8238 (2014).
- Gu Z., Aimetti A., Wang Q., Dang T.T., Zhang Y.L., Veiseh O., Cheng H., Langer R., Anderson D.G. Injectable nano-network for glucose-mediated insulin delivery. ACS Nano 7, 4194-4201 (2013).
- Kastrup C.J., Nahrendorf M., Figueiredo J.L., Lee H., Kambhampati S., Lee T., Cho S-W., Gorbatov R., Iwamoto Y., Dang T.T., Dutta P., Yeon J.H., Cheng H., Pritchard C.D., Vegas A.J., Siegel C.D., MacDougall S., Okonkwo M., Stone J.R., Coury A.J., Weissleder R., Langer R., Anderson D.G. Painting Blood Vessels and Atherosclerotic Plaques with an Adhesive Drug Depot. Proceedings of the National Academy of Sciences of the United States of America 109, 21444-21449 (2012).
- Cheng H., Byrska-Bishop M., Zhang C.T., Kastrup C.J., Hwang N.S., Tai A.K., Lee W.W., Xu X.Y., Nahrendorf M., Langer R., Anderson D.G. Stem cell membrane engineering for cell rolling using peptide conjugation and tuning of cell-selectin interaction kinetics. Biomaterials 33, 5004-5012 (2012).
- Cheng H., Hill P.S., Siegwart D.J., Vacanti N., Lytton-Jean A.K.R., Cho S-W., Ye A., Langer R., Anderson D.G. A novel family of biodegradable poly(ester amide) elastomers. Advanced Materials 23, H95-100 (2011).