Neonatal hypoxia; neurodegeneration

Biomaterials, biomechanics, biochemical engineering

Synthetic Biology, Systems Biology, Bioengineering, Control Theory

Human-centered design, human-computer interaction, human factors, human performance modeling , judgment and decision making, medical informatics, systems engineering

electro optics, medical device development, opthalmic digital photography, entrepreneurship

Spinal Cord Injury, Astrocytes, Experimental Autoimmune Encephalomyelitis, Neuroinflammation, Traumatic Brain Injury, Neuroimmunology, Acquired Brain Injury, Multiple Sclerosis, Neurodegeneration, Neurodegenerative Diseases, Neuroprotection, Neurological Diseases, Immunohistochemistry, Neuroimmunomodulation, Neurobiology, Glioma, Neuron-Glia Interaction, Cognitive Rehabilitation, Cellular Neuroscience, Brain Diseases, EAE, CNS Demyelinating Autoimmune Diseases, Demyelinating Diseases, Molecular Neuroscience, Neuron Culture, Molecular Neurobiology, Neurogenesis, Nervous System Autoimmune Diseases, Neurobiochemistry

Advancing healthcare; biomedical and biochemical engineering for clinical applications; biomaterials for medical devices; innovative teaching models for clinical immersion, experiential learning, and product design.

Integrate physical therapy, basic science and engineering principles through the use of experimental and computational modeling methods to better understand how changes in muscle properties following injury or disease affect physical function, with the goal of developing new technologies and interventions that significantly improve patient care and outcomes.

Self-organization, biomedical image informatics, geometric modeling, computer-aided design and visualization

Algorithms, Brain, Brain Diseases, Brain Mapping, Case-Control Studies, Classical Conditioning, Computer-Assisted Diagnosis, Electromyography, Evoked Potentials, Face, Hemoglobins, Opioid-Related Disorders, Oxygen Pattern Recognition, Automated Personality Disorders, Problem Solving, Signal Processing, Computer-Assisted Spectrophotometry, Infrared Spectroscopy, Near-Infrared Sublimation Unconscious (Psychology), Vocational Guidance

Medical Ethics, Ethics in the Sciences, Neuroethics, Artificial Intelligence, Philosophy of Science, Consilience of Knowledge, Evidence-Based Medicine, Research Methodology, and Environmental Ethics.

Aptamers, riboswitches, allosteric ribozymes

DNA, Gene Expression, RNA, DNA Sequencing, Genomics, Genetics, Sequencing, Bioinformatics and Computational Biology, Gene Regulation, Next Generation Sequencing

Development of oncology therapeutics that target the tumor microenvironment and stimulate the anti-tumor immune response. Responsible for a portfolio of therapies that are in pre-clinical stage through FIH (first in human) and POC (proof of concept) clinical trials.

Software defined/cognitive radio prototyping; reconfigurable, metamaterial, and non-traditional material antennas for wireless systems; smart textiles for biomedical monitoring applications; smart antenna/MIMO systems for wireless communications; sensor networks for air quality and homeland security; free space optical and ultrasonic communication; wireless physical layer security; service learning and cybersecurity education

Contrast enhanced ultrasound imaging and applications, Signal and image algorithms and processing, Applied medical physics research including radiation dose and image quality evaluation, and radiation dose indices, DICOM metadata mining and informatics

Innate immune system, nanoparticles, drug delivery, immune tolerance, T regulatory cells, adjuvant design, Dendritic cell biology, viral targeting, mouse models, autoimmune diseases, transplant immunology, chemical biology, autoinflammatory diseases

Hierarchy and Risk-Taking in the Cockpit, Human-Robotic Performance, Neuroergonomics for Aviation, Functional Neuroimaging, fNIRS, Cognitive Psychology, Human-Computer Interaction, Cognitive Science and Artificial Thinking, Eye Tracking, Prefrontal Cortex, Cognition, Air Traffic Control

Nutrition assessment, malnutrition, inflammation, sarcopenia, frailty, technology, wound healing and interprofessional nutrition assessment competencies

Biomedical ethics and law, healthcare regulatory, and legal issues.

Nephrology, cardiology, electrophysiology, and neurosurgery

Virtual reality applications for cognitive and physical rehabilitation, user-centered assessment of immersive and augmented virtual environments, mathematical modeling for medical applications, visual perception, skill acquisition, naturalistic decision making, brain plasticity

Anesthesiology, fNIR brain monitoring

Bioinformatics, immunology, neural computation, system biology, somatic selection, autoimmunity, genetic stability, germline diversity, dendritic cell, transcription elements, pathogens, computational and mathematical modeling, complex systems, cognition and inflammation

Computational modeling, 3D-printing methodologies, additive manufacturing, blood modulating devices, computational fluid dynamic analysis, mechanical heart valves, fontan assist devices, fluidic circuits, flow visualization methods, and Doppler ultrasound.

Clinical Research, Data Analysis, and Clinical Trials,

Theoretical, experimental, and computational mechanics; nondestructive testing; material multiscale modeling, fatigue, and fracture.

Cardiac repair and regeneration, tissue engineering, cardiovascular system dynamics, systems biology, cellular networks, cardiovascular engineering, telerobotics.

Game design, serious games, game industry, technology

Brain trauma, brain disorders, electric shock injury, biomechanics associated with transportation-related injuries, magnetic resonance imaging (MRI) and the performance of MRI compatibility testing for implantable and accessory devices.

Dr. Clyne's Vascular Kinetics Laboratory conducts research at the interface of engineering, biochemistry, and vascular biology. In their prior work, the group largely focused on how an altered glucose environment (e.g., in diabetes) impaired endothelial cell response to shear stress and cyclic strain. Dr. Clyne and her lab have demonstrated that endothelial cells in high glucose do not respond appropriately to mechanical stimuli. Today, the group focuses primarily on the opposite question: how the mechanical environment affects endothelial cell glucose metabolism. They are integrating mechanobiology and metabolism, with the hope of using metabolic engineering to decrease the burden of cardiovascular disease and cancer. With new collaboration opportunities at the University of Maryland, Dr. Clyne and her lab group plan to extend their cell and animal work into human studies.

Computational modeling, neural modeling, neurorobotics, neuromimetics, neurocontrol, multiple,single neuron recording.

Organ donation, donation after cardiac death, organ donor pool expansion, machine perfusion of donor organs, artificial liver support, transplantation, immunosuppression trials, hepatocellular carcinoma treatments, health care quality improvement, access to healthcare, healthcare economics, medical education and training.

Biomedical signal processing, neurophysiological signals, functional near infrared spectroscopy (fNIRS), electroencephalography (EEG), transcranial direct current stimulation (tDCS), event related potentials (ERPs), somatosensory evoked potentials (SEPs) and electromyography (EMG)

Digital signal processing, machine learning genomics, biological modeling, and chemical source localization and tracking.

Early detection of disease and its progression, focusing on the invention and investigation of novel diagnostics for eye disease, most specifically for glaucoma.

Piezoelectric biosensors, bioimaging, and optoelectronics.

The nucleus of my academic research is in discovering injury thresholds, mechanisms, and treatment strategies for the central nervous system, including the brain and spinal cord.

Vascular Surgery, Wound Care, Minimally Invasive Surgery, Near Infrared Imaging of Wounds

Pediatric engineering, patient safety and optimizing care delivery, bioethics, public health and policy, science communications, medtech innovation, STEMM education, diagnosis and management of disease, identifying healthcare trends, bridging interdisciplinary knowledge gaps to prevent medical error and expedite discovery, thought integration of clinical practice and biomedical engineering approaches with an emphasis on patient-centered design, debunking medical myths and pediatrics.

Web search and mining, security informatics, knowledge management, cross-lingual information retrieval, text summarization, multimedia retrieval, information visualization, information sharing and privacy, digital library, and electronic commerce. His teaching interests include data mining, artificial intelligence, information retrieval, information systems analysis and design.

RF, Microwaves, Power Amplifiers, Circuits and Systems, Signal Processing