Recent Peer-reviewed Publications
"Age-at-injury effects of microglial activation following traumatic brain injury: implications for treatment strategies"
Raghupathi R. and Huh J.W.
Neural Regen. Res. 12:741-42, 2017.
"Factors affecting increased risk for substance use disorders following traumatic brain injury: What we can learn from animal models"
Merkel S.F., Cannella L.A., Razmpour R., Lutton E., Raghupathi R., Rawls S.M. and Ramirez S.H.
Neurosci. Biobehav. Rev. 77:209–218, 2017.
"Strong correlation of genome-wide expression after traumatic brain injury in vitro and in vivo implicates a role for SORLA"
Lamprecht M.R., Elkin B.S., Kesavabhotla K., Crary J.F., Hammers J.L., Huh J.W., Raghupathi R. and Morrison B. 3rd
J Neurotrauma. 34:97-108, 2017.
"Differential effects of minocycline on microglial activation and neurodegeneration following closed head injury in the neonate rat"
Hanlon L.A., Raghupathi R. and Huh J.W.
Exp. Neurol. 290:1-14, 2017.
"Minocycline Transiently Reduces Microglia/Macrophage Activation But Exacerbates Cognitive Deficits Following Repetitive Traumatic Brain Injury in the Neonatal Rat"
Hanlon L.A., Huh J.W. and Raghupathi R.
J. Neuropathol. Exp. Neurol. 75:214-226, 2016.
"Neuroprotective effects of the glutamate transporter activator, MS-153, following traumatic brain injury in the adult rat"
Fontana A.C., Fox D.P., Zoubroulis A., Mortensen O.V. and Raghupathi R.
J. Neurotrauma 33:1073-1083, 2016.
"Spinal Cord Concussion: Studying the Risks of Repetitive Injury"
Fischer I., Haas C., Raghupathi R., and Jin Y.
Neural Regen. Res. 11:58-60, 2016.
"Combination Therapies for Traumatic Brain Injury: Retrospective Considerations"
Margulies S., Anderson G., Atif F., Badaut J., Clark R., Empey P., Guseva M., Hoane M., Huh J., Pauly J., Raghupathi R., Scheff S., Stein D., Tang H. and Hicks R.
J. Neurotrauma 33:101-112, 2016.
"Genetics and Pathology of Chronic Traumatic Encephalopathy"
Krafjack L.L. and Raghupathi R.
Curr. Genet. Med. Reports 3:191-195, 2015.
"Cathepsin L mediates the degradation of novel APP C-terminal fragments"
Wang H., Sang N., Zhang C., Raghupathi R., Tanzi R.E. and Saunders A.
Biochem. 54:2806-2816, 2015.
"Experimental traumatic brain injury alters ethanol consumption and sensitivity"
Lowing J.L., Susick L.L, Caruso J.P., Provenzano A.M., Raghupathi R. and Conti A.C.
J Neurotrauma. 31:1700-1710, 2014.
Reviews and Book Chapters
"Calpain as a therapeutic target for traumatic brain injury"
Saatman KE, Creed J and Raghupathi R
Neurotherapeutics 7:31-42, 2010.
"New concepts in treatment of pediatric traumatic brain injury"
Huh JW and Raghupathi R
Anesthesiol. Clin. 27:213-40, 2009.
"Neurointensive care for traumatic brain injury in children"
Su F, Huh JW, Raghupathi R
http://www.emedicine.com/ped/topic3082.htm, updated July 2009.
"Shaken Baby Syndrome"
Martin HA, Woodson A, Christian CW, Helfaer MA, Raghupathi R, Huh JW, in Critical Care Nursing Clinics of North America, Thompson HJ and Alexy EM, Eds., 18:279-286, 2006.
"Cell death mechanisms following traumatic brain injury"
Brain Pathol. 14:215-222, 2004.
"Apoptosis and DNA Damage in Head Trauma"
Head Trauma: Basic, Preclinical and Clinical Aspects. John Wiley & Sons, Inc., NY: 239-255, 2001.
"Drugs in the Management of Acute TBI"
Raghupathi R, McIntosh TK
Physical Medicine and Rehabilitation Clinics of North America 8:629-649, 1997.
Patent No. US 6,326,146: O'Dell DM, Raghupathi R, McIntosh TK, Crino P, Eberwine J
Method of determining multiple mRNAs in dying cells. 2001.