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Linda Console-Bram

Linda Console-Bram, PhD, MS

Associate Professor

Department: Pharmacology & Physiology


  • PhD - Pharmacology, Temple University School of Medicine (1996)
  • MS - Pharmacology, Saint Joseph’s University (previously Philadelphia College of Pharmacy & Science) (1987)

Awards & Honors

  • Treasurer, Mid-Atlantic Pharmacology Society (MAPS) Regional Chapter of the American Society for Pharmacology and Therapeutics (ASPET) (2013-present)
  • Nominee, Temple University Lewis Katz School of Medicine (LKSOM) Educational Service Award (2021)
  • NIDA P30 Center Grant, Preliminary Data Grant Support (2015)
  • Sigma Xi Research Society (1987)

Linda Console-Bram, MS, PhD, is an associate professor in the Department of Pharmacology & Physiology at Drexel University College of Medicine. She is the pharmacology thread director in the Foundations and Frontiers curriculum at the West Reading/Tower Health campus. Currently her educational roles include preparation of pharmacology independent learning modules in the Foundations of Disease and Human Disease courses as well as facilitation of pharmacology active learning sessions, including simulations, team based- and case-based learning. Dr. Console-Bram is also a facilitator in the Case-Based Learning course for second-year medical students. She recognizes that learners actively engage in knowledge acquisition in different ways via different modalities and strives to develop meaningful independent and active learning sessions to enable learner recall and retention of knowledge.

Research Overview

The role of endogenous cannabinoid and putative cannabinoid receptors in substance use disorders and in the modulation pain, anxiety and immune function.

Research Interests

Endogenous cannabinoid and putative cannabinoid receptors in substance use disorders, pain, anxiety and immune function.


Dr. Console-Bram’s previous research efforts focused on the elucidating the molecular mechanisms involved in signal transduction of established cannabinoid (CB1 and CB2), and putative cannabinoid receptors (GPR18 and GPR55), in addition to ligand development for the putative cannabinoid receptors. Her research contributed to the understanding of biased agonism and differential second messengers involved in established and putative cannabinoid receptor signaling. The physiologic roles of both established and putative cannabinoid receptors remain an ongoing research interest of Dr. Console-Bram with respect to pain, anxiety, substance use disorders and immune cell function.


“N-arachidonoyl glycine, another endogenous agonist of GPR55”
Console-Bram LM, Ciuciu S.M., Zhao P, Zipkin RE, Abood ME
Biochemical and Biophysical Research Communications. 2017; 90(4):1389-1393. doi: 10.1016/j.bbrc.2017.07.038

“Design, synthesis and biological evaluation of GPR55 agonists”
Fakhouri L, Cook CD, Al-Hunti MH, Console-Bram LM, Hurst DP, Spano MBS, Nasrallah DJ, Caron MG, Barak LS, Reggio PH, Abood ME, Croatt MP
Bioorganic & Medicinal Chemistry. 2017 Aug 15;25(16):4355-4367. doi: 10.1016/j.bmc.2017.06.016

“HIV Tat excites D1 receptor-like expressing neurons from rat nucleus accumbens”
Brailoiu E, Brailoiu GC, Deliu E, Console-Bram LM, Ciuciu AM, Abood ME, Unterwald E
Drug and Alcohol Dependence. 2017 Sep 1;178:7-14. doi: 10.1016/j.drugalcdep.2017.04.015

“Cocaine inhibits store-operated Ca2+ entry in brain microvascular endothelial cells: Critical Role for sigma-1 receptors”
Brailoiu GC, Deliu E, Console-Bram, LM, Soboloff J, Abood ME, Unterwald E, Brailoiu E
Biochemical Journal. 2016, 473(1):1-5. doi:10.1042/BJ20150934

“Activation of GPR18: A tale of biased agonism”
Console-Bram L, Brailoiu E, Sharir H, Brailoiu C, Abood ME
British Journal of Pharmacology. 2014 Aug;171(16):3908-17. doi: 10.1111/bph.12746


“Antibiotics and Pharmacology”
Bender, Seltzer and Grossman Academic Review of Endodontology, Temple University Kornberg School of Dentistry, Philadelphia, PA (Virtual session 2021)

“Inclusivity in Small Group Learning”
Office of Health, Equity, Inclusion and Diversity, Lewis Katz School of Medicine at Temple University, Philadelphia, PA (2021)

“How to respond to racial bias in the medical learning environment”
The Richard Kozera Teaching Academy, Lewis Katz School of Medicine at Temple University, Philadelphia, PA (2020)

“GPR18, another cannabinoid receptor?”
Cornell University, Weil Medical College G-Protein Signaling Workshop, Thomas Jefferson University, Philadelphia, PA (2014)

Contact Information

West Reading Campus
50 Innovation Way
Wyomissing, PA 19610