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Chaiken Research Group

We use a combination of chemical and biological approaches to investigate the fundamental nature of protein interactions in solution, viruses and cells, and their roles in disease pathogenesis. The current focus is to determine the interaction mechanisms of HIV-1 cell entry and to design mechanism-based HIV-1 envelope protein inactivators for AIDS prevention and treatment.

We currently receive research funding from National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, W. W. Smith Charitable Trust, and the Campbell Foundation.

We collaborate with research groups in Drexel University and Drexel University College of Medicine, Columbia University, University of Pennsylvania, Johns Hopkins University, Dana Farber Cancer Institute – Harvard University, Yale University, Cornell University and the Chinese Academy of Science, Shanghai.

Chaiken Research Group In the News

"A New Weapon Against HIV: Inactivation of gp120 with Peptide Triazoles" (2016)

"The Campbell Foundation Awards Grant to HIV/AIDS Researcher to Develop HIV-1 Killer Peptides"
The Campbell Foundation website (May 2, 2016)

"Killer Instinct"
Exel, Drexel's Research Magazine (2014)

"Bursting HIV's Bubble" (October 19, 2013)

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The Chaiken Research Group investigates the fundamental nature of protein interactions in solution and in cells, and their roles in disease pathogenesis.