Cryogenic liquids, or Cryogens, are liquefied gases that are kept in their liquefied state at very low temperatures.  Typically, cryogenic liquids have boiling points below -51oC (-60oF or 222K). All cryogenic liquids are extremely cold and small amounts of liquid may expand into very large volumes of gases when heated, even when exposed to room temperatures. This may displace oxygen as they evaporate, leading to asphyxiation.

Always wear appropriate personal protection equipment, including loose fitting insulated gloves made for cryogenic work, face shield used in combination with splash goggles or safety glasses, and appropriate apron, lab coat, or coveralls. Appropriate laboratory attire must be worn while handling cryogenic liquids (long pants, closed top toed/top shoes).

Cryogenic liquids must be stored in well ventilated areas. EH&S may require oxygen level detectors in certain situation due to the gas expansion ratio of cryogenic liquids.

Review the Clinical Safety Manual for a detailed discussion on the proper use and handling of cryogenic liquids. In addition, EH&S developed a chemical safety summary (CSS) for handling cryogenic liquids. You can contact EH&S to request a copy of the CSS.