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Longjian Liu, MD, PhD, MSc, FAHA

Longjian Liu

Professor of Epidemiology and Biostatistics
Epidemiology and Biostatistics
267.359.6049
ll85@drexel.edu
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Degrees

MD, Shanxi Medical University (SMU), Taiyuan, China
PhD in Epidemiology, The University of Hong Kong, China
MSc in Epidemiology, The University of London School of Hygiene and Tropical Medicine, UK
Bachelor’s Degree in Medicine and Medical Doctor in Preventive Medicine, SMU, Taiyua, China

Bio

Dr. Longjian Liu is a tenured Full Professor of Epidemiology at Drexel University’s Dornsife School of Public Health, with an adjunct appointment at the College of Medicine. He previously served as the Interim Chair of the Department of Environmental and Occupational Health.

With extensive training in medicine, public health, and epidemiology from institutions in China, the UK, and Hong Kong, Dr. Liu's research focuses on cardiometabolic diseases, brain aging, and global health disparities. He is a Fellow of the American Heart Association and has published over 100 peer-reviewed articles, textbooks, and book chapters.

Dr. Liu has led and collaborated on numerous NIH-funded studies, utilizing major U.S. datasets like MESA, ARIC, and NHANES, as well as international cohorts from Japan, China, and the World Health Organization. His research interests include:

  • Cardio-kidney-metabolic (CKM) disorders and vascular outcomes
  • The interplay between CKM disorders, genetics, and brain aging/dementia
  • Applying AI and machine learning to enhance outcomes research and predictive modeling
  • Analyzing longitudinal studies and electronic health record (EHR) data

Since joining Drexel in 2005, Dr. Liu has taught undergraduate and graduate courses and mentored numerous students. His prior academic appointments include positions in China, Japan, and the U.S. University of Arkansas for Medical Science.

Courses

  • EPI 749, EPI 557, EPI 559, EPI 570, EPI 572
  • PBHL 301, PBHL 310, and PBHL 311
  • Mentoring MPH, MS, and PhD students’ research projects

Research Interests

  • Global health in Chronic Disease and mHealth
  • Cardiometabolic Disorders and Health Disparities
  • Neurodevelopment and Neurologic Disorders
  • Pharmacoepidemiology
  • Health Failure Epidemiology
  • AI/Machine Learning Enabled Risk Prediction Models

Publications

Selected publications

Longjian Liu, Edward J Gracely, Xiaopeng Zhao, Gediminas P Gliebus, Nathalie S. May, Stella L. Volpe, Jingyi Shi, Rose Ann DiMaria-Ghalili, and Howard J Eisen: Association of Multiple Metabolic and Cardiovascular Markers with Risk of Cognitive Decline and Mortality in Those with Alzheimer’s Disease and AD-related Dementia: A Prospective Cohort Study. Frontiers in Aging Neuroscience, 2024;2:16, PMCID: PMC11020085.

Ziming Liu, Longjian Liu, Robert E. Heidel, Xiaopeng Zhao: Explainable AI and transformer models: Unraveling the nutritional influences on Alzheimer's disease mortality. Smart Health, Volume 32, 100478, June 2024. PubMed PMID: 39087069. PMCID: PMC11290104.

Alexander Alsup, Emily Nissen, Lucas A. Salas, Annette M. Molinaro, Alexander Reiner, Simin Liu, Tracey Madsen, Longjian Liu, Brock C. Christensen, John K. Wiencke, Karl T. Kelsey, Devin C. Koestler: An Assessment of Compositional Methods for the Analysis of DNA Methylation-based Deconvolution Estimates. Epigenomics (Taylor & Francis, UK), publication online first on Aug02, 2024. PMID: 39093129

Longjian Liu, Nathalie S May, Priscila Y Sato, Paakhi Srivastava, and Leslie McClure: Association between Cardiovascular Risk and Coronavirus disease 2019: Findings from 2021 National Health Interview Survey. Annal Epidemiology, 2023, 23;82:1-7. PMCID: PMC10033151.

Julianne T Nelson and Longjian Liu: Pharmacoepidemiologic Study of Association between Apparent Treatment Resistant Hypertension, Cardiovascular Disease and Interaction Effect by Sex and Age. World Journal of Cardiology, 2023, 15(5):262-272, PMCID: PMC10237003.

Longjian Liu, Kathleen M. Hayden, Nathalie S. May, Bernhard Haring, Zuolu Liu, Victor W. Henderson, Jiu-Chiuan Chen, Edward J Gracely, Sylvia Wassertheil-Smoller, and Stephen R. Rapp: Association Between Blood Pressure Levels and Cognitive Impairment in Older Women: A Prospective Analysis of The Women’s Health Initiative Memory Study. The Lancet Healthy Longevity, Jan 2022, PMCID: PMC8804967.

Longjian Liu, Stella L. Volpe, Jennifer A Ross, Elisabeth J Van Bockstaele, and Howard J Eisen: Dietary Sugar Intake and Risk of Alzheimer’s Disease in Older Women. 2021 June, Nutritional Neuroscience. PubMed PMID 34328409.

Longjian Liu, Joao Lima, Wendy S Post, and Moyses Szklo: Association of obesity and metabolic syndrome with risk of heart failure and its subtypes in the Multi-Ethnic Study of Atherosclerosis. International Journal of Cardiology, June 2021, PubMed PMID: 34089770.

Longjian Liu, Liviu Klein; Charles Eaton; Gurusher Panjrath; Lisa Warsinger Martin; Claudia U. Chae; Philip Greenland; Donald M Lloyd-Jones; Jean Wactawski-Wende; and JoAnn E. Manson: Menopausal Hormone Therapy and Risks of First Hospitalized Heart Failure and Its Subtypes During the Intervention and Extended Postintervention Follow-up of the Women’s Health Initiative Randomized Trials. Journal Cardiac Failure, 2020 26(1)2-12. PubMed PMID: 3156806.

Longjian Liu, Julianne Nelson, Craig J. Newschaffer, and Patrick L. Remington, Ross C. Brownson, and Mark V. Wegner: Chapter 16: Cardiovascular Disease in APHA coordinated textbook: Chronic Disease Epidemiology, Prevention, and Control, 5th edition, American Public Health Association Press, Oct 2023.

See Dr. Lui's full list of key publications on PubMed