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Brian Lee, PhD

Brian Lee headshot

Associate Professor of Epidemiology
Epidemiology and Biostatistics
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AB, Biological Anthropology, Harvard College; MHS, Epidemiology, Johns Hopkins University; PhD, Epidemiology, Johns Hopkins University


Dr. Lee received his PhD and MHS degrees in Epidemiology from The Johns Hopkins University, and graduated Cum laude with an AB in Biological Anthropology from Harvard College. His research interests include the epidemiology of neurological development, maintenance and decline.  Current topics include prenatal environmental exposures and autism risk; neighborhoods and psychosocial "stress" in the cognitive decline of older adults; lead toxicity and white matter health; gene-environment interaction; maternal antibody exposure in utero and fetal outcomes.  In addition to his etiological research, Dr. Lee is interested in epidemiological methods including causal inference methodology, data mining and machine learning algorithms, and automated data extraction techniques for structured and unstructured data.

Google Scholar profile

Research Interests

  • Data Analysis Methods
  • Maternal and Child Health
  • Mental health and Behavioral health
  • Neurodevelopment and Neurologic disorders


Shen H, Magnusson C, Rai D, Lundberg M, Le-Scherban F, Dalman C, Lee BK. Associations of parental depression with child school performance at age 16 in Sweden. JAMA Psychiatry, in press.

Gidaya NB, Lee BK, Burstyn I, Michael YL, Newschaffer CJ, Mortensen E. In utero exposure to B-2-adrenergic receptor agonist drugs and risk for autism spectrum disorders. Pediatrics, 2016 Jan 6. pii: peds.2015-1316.

​Mayne S, Lee BK, Auchincloss AH. Evaluating Propensity Score Methods in a Quasi-experimental Study of the Impact of Menu-Labeling. PLoS ONE, 2015: 10(12).

Kosidou K, Dalman C, Widman L, Arver S, Lee BK, Magnusson C, Gardner RM. Maternal polycystic ovary syndrome and the risk of autism spectrum disorders in the offspring: a population-based nationwide study in Sweden. Molecular Psychiatry, 2015: 1-8.

Idring S, Lundberg M, Sturm H, Dalman C, Gumpert C, Rai D, Lee BK, Magnussson C. Changes in prevalence of autism spectrum disorders in 2001-2011: findings from the Stockholm Youth Cohort. Journal of Autism and Developmental Disorders, 2015 Jun;45(6):1766-73.

Lee, BK McGrath JJ. Advancing parental age and autism: multifactorial pathways. Trends in Molecular Medicine 2015 Feb;21(2):118-25.

Lee BK, Magnusson C, Gardner RM, Blomström A, Newschaffer CJ, Burstyn I, Karlsson H, Dalman C. Maternal hospitalization with infection during pregnancy and risk of autism spectrum disorders. Brain, Behavior, and Immunity, 2015 Feb;44: 100-5.

Idring S, Magnusson C, Lundberg M, Rai D, Svensson AC, Dalman C, Karlsson H, Lee BK. Parental age and the risk of autism spectrum disorders – findings from a Swedish population-based cohort. International Journal of Epidemiology, 2014 Feb;43(1):107-15.

Lee BK, Glass TA, James BD, Bandeen-Roche K, Schwartz BS.  Neighborhood psychosocial environment, apolipoprotein E genotype, and cognitive function in older adults. Archives of General Psychiatry, 2011 Mar;68(3):314-21.

Lee BK, Lessler J, Stuart EA. Improving propensity score weighting using machine learning. Statistics in Medicine, 2010 Feb 10;29(3):337-46.


Spring PBHL 834  Advanced Epidemiology 2: Methodologic Challenges