For a better experience, click the Compatibility Mode icon above to turn off Compatibility Mode, which is only for viewing older websites.

David Topolsky

David Topolsky, MD

Associate Professor

Department: Medicine: Division of Hematology/Oncology

Practices: Drexel Hematology and Oncology, Drexel Cancer Care

Specialties: Hematology / Oncology


  • MD - Hahnemann University (1982)
  • BA - Temple University (1978)
  • University of Southern California (1975)

David Topolsky, MD, is a hematologist and medical oncologist practicing in Center City Philadelphia. He is board certified in internal medicine, medical oncology and hematology. He served as medical director of Hahnemann University Hospital's national marrow donor transplant center and co-medical director of the stem cell processing lab.


  • American Society of Hematology
  • American Society of Clinical Oncology
  • Eastern Cooperative Oncology Group
  • Philadelphia Bone Marrow Transplant Group
  • American Society for Blood and Marrow Transplantation
  • American Medical Association
  • Philadelphia County Medical Society
  • Phi Beta Kappa
  • Alpha Omega Alpha

Clinical Services

Internal medicine, Hematology, Oncology, Medical oncology


  • Hematology/Oncology - Hahnemann University Hospital (1988)


  • Internal Medicine - Hahnemann University Hospital (1985)


  • Internal Medicine - Hahnemann University Hospital (1983)

Dr. Topolsky is an associate professor of medicine in the Division of Hematology & Oncology at Drexel University College of Medicine. His teaching responsibilities include the topics of leukemia and lymphoma in the Introduction to Clinical Medicine course, as well as various topics in hematology and oncology for residents and fellows.


Recent Publications

"High-dose cyclophosphamide with the treatment of Multiple Sclerosis"
Schwartzman RJ, Simpkins N, Alexander GM, Reichenberger E, Ward K, Lindenberg N, Topolsky D, Crilley P
CNS Neuroscience & Therapeutic 15(2): 118-27, 2009

"Late Mortality and Relapse following BuCy2 and HLA-identical Sibling Marrow Transplantation for Chronic Myelogenous Leukemia"
Copelan E, Crilley P, Szer J, Dodds AJ, Stevenson D, Phillips G, Nivison-Smith I, Avalos BR, Penza S, Topolsky D, Sobecks R, Kalaycio M, Bolwell BJ
Biology Blood Marrow Transplant 15:851-855, 2009

"Alveolar hemorrhage associated with platelet glycoprotein IIb/IIIa receptor inhibitors"
Ener RA, Bruno N, Dadorcian D, Wolf N, Van Pedcer W, Burke J, Styler M, Topolsky D
Journal of Invasive Cardiology 18 (6): 254-64 June 2006

Recent Abstracts

"Mean Platelet Volume Predicts Platelet Engraftment Post Hematopoietic Stem Cell Transplantation"
W Dhillon, MD, P Lothe, MD, K Ward, MD, P Crilley, DO, D Topolsky, MD, M Styler, MD
Blood, 122: 5507, October 2013

"G-CSF Dose Escalation Starting Day 8 after Salvage RICE Chemotherapy Results in Adequate and Predictable Autologous Peripheral Blood Stem Cell Collection in Relapsed/Refractory Lymphoma"
A Weber, P Pillai, M Styler, D Topolsky, K Ward, R Mullaney, P Crilley
ASBMT 2011, Hawaii, Abstract Accepted

"Invasive Rhino-Cerebral Mucormycosis"
P Pillai, P Crilley, K Ward, D Topolsky, M Styler
Manuscript Draft submitted to: Elsevier Editorial System™ for The Lancet Infectious Disease

"Chronic GVHD presenting as Delayed Onset Polymyositis after Allogeneic Bone Marrow Transplantation"
P Pillai, R Vatanparast, A Weber, JM Kane, M Styler, D Topolsky, K Ward, R Mullaney, CD Katsetos, P Crilley
Abstract # 70057, BMT Tandem Meeting, 2011

"Evaluation of the Pre-Test Scoring System (4Ts) for the Evaluation and Management of Heparin Induced Thrombocytopenia"
R Vatanparast, P Pillai, G Crane, S Minter, K Ward, D Topolsky, M Styler, P Crilley
ASH Abstract #26816, ASH Presentation, December 4-7, 2010

"Validation of the European Practice Guidelines for the Use of Recombinant Activated Factor VII in Patients with Massive Bleeding"
P Pillai, R Ranganathan, R Vatanparast, R Reddimallu, S Lantz, L Bachegowda, K Ward, M Styler, D Topolsky, P Crilley
ASH Abstract #32260, ASH Presentation, December 4-7, 2010
Poster Presentation #122, Drexel Discovery Day, September 2010

"Clinical and pathologic outcome analysis with the preoperative systemic therapy in operable breast cancer"
P Pillai, Y Ma, VK Sandilya, J Innocent, RR Rubin, N Popnikolov, D Topolsky, P Crilley, L Newman, M Styler
J. Clin Oncology 28, (suppl; abstr e11094), 2010

"Haplo Identical (Partially HLA Mismatched, Related Donor) Non-Myeloablative Bone Marrow Transplantation: Hahnemann University Hospital Experience"
P Pillai, M Styler, D Topolsky, K Ward, R Mullaney, K Skinner, P Crilley
DrexelMed Journal, Volume 4 (1); Summer 2010
Poster Presentation # 118, Drexel Discovery Day, Sept 2009

"Breakthrough Invasive Mucor Mycosis in an Immunocompromised Patient while on Voriconazole Prophylaxis: A Case Report"
RS Alur, J Innocent, P Prasad, F Troicki, C Gao, P Ojha, Y Gong, K Ward, M Styler, D Topolsky, H Schlecht, M Nagorsky, L. Komarnicky, P Crilley
Poster Presentation # 117, Drexel Discovery Day, Sept 2009

Contact Information

Practice Office

Drexel Hematology/Oncology (I. Brodsky Associates)
230 N. Broad Street
15th Floor South Tower, Hahnemann University Hospital
Philadelphia, PA 19102
Phone: 215.762.7735
Fax: 215.762.4877