Drexel-Sidney Kimmel Comprehensive Cancer Center/TJU Biacore S200 Surface Plasmon Resonance (SPR) Biosensor Shared Instrument Facility AAR029b (macrocyclic peptide) Binding to HIV-1 Env CD4 Binding Pocket HIV-1 YU2 gp120 ligand immobilized on CM5 sensor chip and AAR029b injected at increasing concentrations. AAR029b Macrocyclic Peptide MW: 1003.4 Da AAR029b (green sticks) docked into an HIV-1 trimer (5FUU) CD4 binding pocket. Red residues: W112 and S375. Rashad et al., J Med Chem. 2015; 58(18): 7603–7608. Red arrows reveal the increased sensitivity and power of Biacore S200 compared to Biacore 3000. Technology Learn More Equipment Learn More Services Learn More Contact Us Learn More Back to Top
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