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Alison J. Carey

Alison J. Carey, MD

Associate Professor

Department: Microbiology & Immunology, Pediatrics

Specialties: Neonatal-Perinatal Medicine, Pediatrics


  • Georgetown University School of Medicine

Awards & Honors

  • Mid-Career Clinical Scientist Award, Drexel University College of Medicine (2024)
  • Named "Top Doctor" by Philadelphia Magazine (2018, 2021, 2024)
2024 Philadelphia Magazine Top Doctors™

Alison Carey, MD, is an attending neonatologist at St. Christopher's Hospital for Children.

  • Named "Top Doctor" by Philadelphia magazine (2018, 2021, 2023, 2024)

Clinical Services

Pediatrics, Neonatal care


  • Robert Wood Johnson University Hospital


  • Columbia University

Alison J. Carey, MD, is an associate professor of pediatrics at Drexel University College of Medicine.

Read Dr. Carey's faculty highlight from the Women in Medicine and Science Committee.

Research Overview

Dr. Carey's research seeks to identify mechanisms and potential modifiable risk factors for infants' susceptibility to infections using animal models, in vitro work and ex vivo studies on human cord blood. Her lab has established a clinically relevant model of neonatal influenza virus infection in 3-day-old neonatal mice in order to focus on both the adaptive and innate immune response to viral infection.

Dr. Carey was awarded a biomedical research grant from the American Lung Association for her project, "Identification of the Toll-like Receptor Mediating Lactobacillus rhamnosus Protection in Neonatal Mice." Her research was also highlighted on their website.

Research Interests

Mechanisms of age-specific host-pathogen responses, respiratory viral infections, infant immune system development, type I interferon response


See Alison Carey's bibliograpy in PubMed.

"Severity of neonatal influenza infection is driven by type I interferon and oxidative stress"
Kumova OK, Galani IE, Rao A, Johnson H, Triantafyllia V, Matt SM, Pascasio J, Gaskill PJ, Andreakos E, Katsikis PD, Carey AJ
Mucosal Immunol. 2022 Jun;15(6):1309-1320. doi: 10.1038/s41385-022-00576-x. Epub 2022 Nov 9. PubMed PMID: 36352099; PubMed Central PMCID: PMC9724789

"Evaluation of the applicability of the current CDC pediatric ventilator-associated events (PedVAE) surveillance definition in the neonatal intensive care unit population"
Arthur N, Kaur I, Carey AJ
BMC Pediatr. 2022 Apr 7;22(1):185. doi: 10.1186/s12887-022-03236-y. PubMed PMID: 35392855; PubMed Central PMCID: PMC8988311

"Reduction of Unnecessary Antibiotic Days in a Level 4 Neonatal Intensive Care Unit"
Vyas DP, Quinones-Cardona V, Gilfillan MA, Young MA, Pough KA, Carey AJ
Antimicrobial Stewardship and Hosp. Epidem.. 2022 March; 2(1):E50

"Eliminating Contamination in Umbilical Cord Blood Culture Sampling for Early-Onset Neonatal Sepsis"
Quinones Cardona V, Lowery V, Cooperberg D, Anday EK, Carey AJ
Front Pediatr. 2021;9:794710. doi: 10.3389/fped.2021.794710. eCollection 2021. PubMed PMID: 34988042; PubMed Central PMCID: PMC8721114

"Chitin-Derived AVR-48 Prevents Experimental Bronchopulmonary Dysplasia (BPD) and BPD-Associated Pulmonary Hypertension in Newborn Mice"
Das P, Acharya S, Prahaladan VM, Kumova OK, Malaeb S, Behera S, Agarwal B, Christensen DJ, Carey AJ, Bhandari V
Int J Mol Sci. 2021 Aug 9;22(16). doi: 10.3390/ijms22168547. PubMed PMID: 34445253; PubMed Central PMCID: PMC8395179

"Lung transcriptional unresponsiveness and loss of early influenza virus control in infected neonates is prevented by intranasal Lactobacillus rhamnosus GG"
Kumova OK, Fike AJ, Thayer JL, Nguyen LT, Mell JC, Pascasio J, Stairiker C, Leon LG, Katsikis PD, Carey AJ
PLoS Pathog. 15(10): e1008072. PMID: 31603951 (2019)

"Dissecting the defects in the neonatal CD8+ T Cell response"
Fike AJ, Kumova OK, Carey AJ
J. Leukocyte Biol. 106(5): 1051-61. PMID: 31260598 (2019)

"Neonatal influenza-specific CD31+CD8+ T cells have decreased IFNγ production and T-bet expression"
Fike AJ, Kumova OK, San Martin V, Carey AJ
J. Leukocyte Biol.; 105(3):539-549. PMID: 30536476 (2019)

"Public Clonotypes and Convergent Recombination Characterize the Naïve CD8+ T-cell Receptor Repertoire of Extremely Preterm Neonates"
Carey AJ, Hope JL, Mueller YM, Fike AJ, Kumova OK, van Zessen DBH, Steegers EAP, van der Burg M, Katsikis PD
Frontiers in Immunology. 8:1859 (2017)

"Characterization of CD31 expression on murine and human neonatal T lymphocytes during development and activation"
Fike AJ, Nguyen LT, Kumova OK, Carey AJ
Pediatr Res.; 82(1):133-140. PMID: 28355204 (2017)

"Rapid Evolution of the CD8+ TCR Repertoire in Neonatal Mice"
Carey AJ, Gracias DT, Thayer JL, Boesteanu AC, Kumova OK, Mueller YM, Hope JL, Fraietta JA, van Zessen DB, Katsikis PD
J Immunol. pii: 1502126. [Epub ahead of print] PubMed PMID: 26873987 (February 12, 2016)

"Phosphatidylinositol 3-Kinase p110δ Isoform Regulates CD8+ T Cell Responses during Acute Viral and Intracellular Bacterial Infections"
Gracias DT, Boesteanu AC, Fraietta JA, Hope JL, Carey AJ, Mueller YM, Kawalekar OU, Fike AJ, June CH, Katsikis PD
J Immunol. 196(3):1186-98. doi: 10.4049/jimmunol.1501890. Epub 2016 Jan 6. PubMed PMID: 26740110 (February 1, 2016)

"Prevention of unplanned extubations in neonates through process standardization"
Fontánez-Nieves TD, Frost M, Anday E, Davis D, Cooperberg D, Carey AJ
J Perinatol. doi: 10.1038/jp.2015.219. [Epub ahead of print] PubMed PMID: 26796128 (January 21, 2016)

"War on Staphylococcus aureus"
Carey AJ
J Perinatol. 34(11):803-4. doi: 10.1038/jp.2014.129. PubMed PMID: 25359411 (November 2014)

"Staphylococcus aureus: a continuously evolving and formidable pathogen in the neonatal intensive care unit"
Carey AJ, Long SS
Clin Perinatol. 37(3):535-46. doi: 10.1016/j.clp.2010.05.002. Review. PubMed PMID: 20813269 (September 2010)

"Changes in the molecular epidemiological characteristics of methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit"
Carey AJ, Della-Latta P, Huard R, Wu F, Graham PL 3rd, Carp D, Saiman L
Infect Control Hosp Epidemiol. 31(6):613-9. doi: 10.1086/652526. PubMed PMID: 20420500 (June 2010)

"The epidemiology of methicillin-susceptible and methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit, 2000-2007"
Carey AJ, Duchon J, Della-Latta P, Saiman L
J Perinatol. 30(2):135-9. doi: 10.1038/jp.2009.119. Epub 2009 Aug 27. PubMed PMID: 19710681 (February 2010)

"Hospital-acquired infections in the NICU: epidemiology for the new millennium"
Carey AJ, Saiman L, Polin RA
Clin Perinatol. 35(1):223-49, x. doi: 10.1016/j.clp.2007.11.014. Review. PubMed PMID: 18280884 (March 2008)

Contact Information

St. Christopher's Hospital for Children
160 East Erie Avenue
Philadelphia, PA 19134
Phone: 215.427.5000
Fax: 215.427.5555