Selected Peer-Reviewed Publications:

Mechanobiology, Mechanotransduction and Mechano-electric Coupling

“Augmentation of integrin-mediated mechanotransduction by hyaluronic acid”
Chopra A, Murray ME, Byfield FJ, Mendez MG, Halleluyan R, Restle DJ, Raz-Ben Aroush D, Galie PA, Pogoda K, Bucki R, Marcinkiewicz C, Prestwich GD, Zarembinski TI, Chen CS, Pure E, Kresh JY, Janmey PA
Biomaterials. 2014 Jan;35(1):71-82.

“Intercellular and extracellular mechanotransduction in ardiac myocytes”
Kresh JY, Chopra A
Pflugers Arch. 2011 Jul; 462(1):75-87. Epub 2011 Mar 25. PMID: 21437600.

“Cardiac myocyte remodeling mediated by N-cadherin-dependent mechanosensing”
Chopra A, Tabdanov E, Patel H, Janmey PA, Kresh JY
Am J Physiol Heart Circ Physiol. 2011 Apr; 300(4):H1252-66. Epub 2011 Jan 21. PubMed PMID: 21257918; PMCID: PMC3075038.

“Mechanically-stimulated contraction of engineered cardiac constructs using a microcantilever”
Galie PA, Byfield FJ, Chen CS, Kresh JY, Janmey PA
IEEE TBME 2014; 62(2):438-442.

Myocardial Regeneration and Cell Replacement

“Cardiomyocyte-mediated contact programs human mesenchymal stem cells to express cardiogenic phenotype”
Rangappa S, Entwistle JW, Wechsler AS, Kresh JY
J Thorac Cardiovasc Surg. 2003 Jul;126(1):124-32. PMID: 12878947.

“Cell replacement therapy: the functional importance of myocardial architecture and intercellular gap-junction distribution”
Kresh JY
J Thorac Cardiovasc Surg. 2006 Jun; 131(6):1310-3. PMID: 16733163

Cardiac Transplantation, Heart-Brain Interaction

“Evolution in functional complexity of heart rate dynamics: a measure of cardiac allograft adaptability”
Kresh JY, Izrailtyan I
Am J Physiol. 1998 Sep; 275(3 Pt 2):R720-7. PMID: 9728068.

“The heart as a self-regulating system: integration of homeodynamic mechanisms”
Kresh JY, Armour JA
Technol Health Care. 1997 Apr; 5(1-2):159-69. PMID: 9134627.

“Bradykinin modulation of isolated rabbit heart function is mediated by intrinsic cardiac neurons”
Izrailtyan I, Kresh JY
Cardiovasc Res. 1997 Mar; 33(3):641-9. PMID: 9093534.

“Early detection of acute allograft rejection by linear and nonlinear analysis of heart rate variability”
Izrailtyan I, Kresh JY, Morris RJ, Brozena SC, Kutalek SP, Wechsler AS
J Thorac Cardiovasc Surg. 2000 Oct;120(4):737-45. PubMed PMID: 11003757.

Mechanically Assisted Circulation – Physiology and Devices

“Circulatory Mechanotherapeutics: Moving with the Force”
Zhang PH, Kresh JY
Current Cardiology Reports. 2018 August 22;20(10):94.

“Heart Mechanical Assist Device Interaction”
Kresh JY, Kerkhof P, Brockman SK
Transactions ASAIO, Vol. 32, pp. 437 443, 1986.

“Theoretical and Experimental Analysis of Right Ventricular Bypass and Univentricular Circulatory Support”
Kresh JY, Brockman SK, Noordergraaf A
IEEE Transactions on Biomedical Engineering, Vol. 37 No. 2, p.121-127, Feb 1990.

“Heart reduction surgery can reconstitute the residual stress-strain state of the left ventricle”
Kresh JY, Wechsler AS
J Thorac Cardiovasc Surg. 1998 Dec; 116(6):1084-6. PMID: 9832707.

“Physiologic and hemodynamic basis of ventricular assist devices”
Bolno PB, Kresh JY
Cardiol Clin. 2003 Feb; 21(1):15-27. PubMed PMID: 12790041.

Cardiac Mechanics –Myocardial Perfusion and Energetics

“Functional Architecture of the Heart: Torsional Contraction and Spiral Flow.”
Kresh JY, Huang Zhang P, Eisen H
ISHLT Links, Volume 8, Issue 8, December 2016.

“Intramyocardial pressure: interaction of myocardial fluid pressure and fiber stress”
Rabbany SY, Kresh JY, Noordergraaf A
Am J Physiol. 1989 Aug; 257(2 Pt 2):H357-64. PMID: 2764124.

“Model Based Analysis of Transmural Vessel Impedance and Myocardial Circulation Dynamics”
Kresh JY, Fox M, Brockman SK
Am. J. Physiol., 258, (Heart Circulation Physiology, 27), H262-276, 1990.

“Myocardial Modulation of Coronary Circulation”
Kresh JY
American Journal of Physiology, Vol. 259, pp. H1934-1937, 1990.

“Effects of venous pressure on coronary circulation and intramyocardial fluid mechanics”
Izrailtyan I, Frasch HF, Kresh JY
Am J Physiol. 1994 Sep; 267(3 Pt 2):H1002-9. PMID: 8092266.

Patents:

Pacing System and Method for Cardiac Pacing As a Function of Determined Myocardial Contractility: U.S. Patent # 4,936,304

Myocardial Contractility-Sensitive Pacer: French and German Patents # 0244446 / 3673643

Acoustic Blood Analyzer for Assessing Coagulation Status U.S. Patent # US7857761 B2

 
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