Plasma Medicine

This work is led by Dr. Suresh Joshi in collaboration with A.J. Drexel Plasma Institute. We are exploring the potential of non-thermal dielectric-barrier discharge plasma in control of infectious agents, disinfection and sterilization; and biological responses of normal and cancerous cells, and studying safety margin through animal toxicity models.

Antimicrobial Drug Resistance and SSI

These projects are led by Dr. Suresh Joshi. There are two focused organisms, Acinetobacter and MRSA, involved in SSI and known to harbor genes for multiple-drug resistance (MDR). The laboratory is engaged in exploring mechanisms and characterization of gene products mediating the resistance. With collaboration from the Department of Biochemistry & Molecular Biology, we are in the process of developing small molecule antibacterial agents, and an effective inhibitors against extended-spectrum beta-lactamase (ESBL), and metalo-beta-lactamase.

Host-Pathogen Interaction

This work is led by Dr. Suresh Joshi. The laboratory is exploring the host cell responses to MDR Acinetobacter virulence factors, and Panton-Valentine Leukocidin toxin from MRSA.