Events
Pharmacology & Physiology Fall 2024 Seminar Schedule
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September 17, 2024
Building “Big Data” Multi-Omic Resources for Cross-Disease Discovery and Clinical Translation: From Collaborative Networks to the Cloud and Back to Patients
Adam Resnick, PhD – Director, Center for Data Driven Discovery in Biomedicine, Alexander B. Wheeler Endowed Chair in Neurosurgical Research, Research Professor of Neurosurgery at the Perelman School of Medicine, Children’s Hospital of Philadelphia
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October 22, 2024
Nociceptor Neuron Interactions with Microbes and Immune Cells in Barrier Immunity
Isaac Chiu, PhD – Associate Professor of Microbiology and Immunobiology, Harvard University Division of Medical Sciences
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November 18, 2024
The Impact of Buprenorphine on Neurocognitive Impairment in EcoHIV Infected Mice: A Potential Therapy for HIV-NCI
Jennifer Kelschenbach, PhD – Assistant Professor, Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai
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November 19, 2024
Amygdala Mechanisms of Incentive Motivational Strategy
Donna Calu, PhD – Associate Professor, Department of Neurobiology, University of Maryland School of Medicine
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December 17, 2024
The Impact of Early Antiretroviral Therapy on HIV-Specific Antibody Responses
Katharine Bar, MD – Associate Professor of Medicine (Infectious Diseases); Director, Penn CFAR Viral and Molecular Core, Perelman School of Medicine, University of Pennsylvania
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June 25, 2024
Impact of Microenvironment on Dopaminergic Immunomodulation in Human Macrophages
Breana Channer – Senior Pharm/Phys Student, Gaskill Lab, Drexel University College of Medicine
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July 9, 2024
Modulation of Astrocytic Calcium Dynamics in Ischemic Stroke Recovery
Geena John – Senior Pharm/Phys Student, Jackson Lab – Drexel University College of Medicine
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July 16, 2024
Allosteric Modulator of Dopamine Transporter Inhibits Cocaine-Induced Hyperlocomotion
Clara Xu – Senior Pharm/Phys Student, O. Mortensen Lab – Drexel University College of Medicine
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July 30, 2024
From Organoids to Therapeutics: Unveiling Genotype-Phenotype Links in Spastic Paraplegia Type 4 with HDAC6 Inhibitors
Neha Mohan – Senior Pharm/Phys Student, Qiang Lab – Drexel University College of Medicine
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August 13, 2024
Development of Glutamate Transporter Modulators as a Non-Opioid Treatment for Neuropathic Pain
Rhea Temmermand – Senior Pharm/Phys Student, A. Mortensen Lab, Drexel University College of Medicine
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January 16, 2024
Perseverance Versus Cognitive Flexibility: Neuronal Glutamate Transporters Give Us a Reason Not to Indulge in Either
Annalisa Scimemi, PhD – Associate Professor, Department of Biological Sciences, University at Albany, SUNY
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February 6, 2024
The Smoking Gun: Organic Cation Transporter 3 in the Actions of Amphetamine and Alcohol
Lynette Daws, PhD – Professor, Department of Cellular & Integrative Physiology, University of Texas San Antonio Health Center
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March 5, 2024
Neuroimmune Interactions Sculpt the Developing Brain
Margaret McCarthy, PhD – Professor & Chair, Department of Pharmacology; Director, University of Maryland - Medicine Institute of Neuroscience Discovery (UM-MIND), University of Maryland School of Medicine
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March 26, 2024
Using Patient-Derived Models for Drug Discovery and Functional Precision Oncology in Advanced Breast Cancer
Alana Welm, PhD – Senior Director of Basic Science, Huntsman Comprehensive Cancer Center; Professor, Department of Oncological Sciences, University of Utah
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April 16, 2024
Neuropathogenic Microglia: Single Cell Analysis in SIV, ARV Treatment, and Drug Abuse
Howard Fox, MD, PhD – Professor, Department of Neurological Sciences; Senior Associate Dean of Research & Development, UNMC College of Medicine; Director, Center for Integrative and Translational Neuroscience; Co-Investigator, Co-Director, Great Plains IDeA-CTR, University of Nebraska Medical Center
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April 30, 2024
More Than Trash Cans: The Lysosome as a Novel Regulator of Oligodendrocyte Function
Lindsay Festa, PhD – Research Associate, Department of Oral Medicine, University of Pennsylvania
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May 7, 2024
Sex Differences in the Molecular and Cellular Mechanisms of Chronic Pain Development
Giannina Descalzi, PhD – Assistant Professor, Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph
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May 14, 2024
Translating the Complex Role of Antiretrovirals in the Brain
Melanie Nicol, PharmD, PhD – Associate Professor & Associate Director of Graduate Studies Department of Experimental & Clinical Pharmacology, University of Minnesota
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September 5
Biomolecular Drug Targets Through the Lens of Computation
Eleonora Gianti, PhD – Associate Professor, Department of Chemistry and Institute for Computational Molecular Science, Temple University
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September 19
Natural Products Drug Discovery for the Eradication of NeuroHIV
Jason Paris, PhD – Research Associate Professor of Pharmacology, Department of BioMolecular Sciences, University of Mississippi
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September 26
Immune Regulation by Small Extracellular Vesicles in Attenuating Inflammatory Pain
Xuan Luo – Senior Pharmacology & Physiology Graduate Student (Ajit lab), Drexel University College of Medicine
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October 10
Cerebrovascular Mitochondria and Apoptotic Mechanisms as Targets in Alzheimer’s Disease
Silvia Fossati, PhD – Associate Professor & Associate Director, Alzheimer’s Center at Temple; Associate Professor, Department of Neural Sciences & Lemole Center for Integrated Lymphatics Research, Temple University Lewis Katz School of Medicine
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October 24
Phenotypic Plasticity of CX3CR1 is Associated with Metastasis Initiation
Anna Zhang – Senior Pharmacology & Physiology Graduate Student (Fatatis lab), Drexel University College of Medicine
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October 31
Immune Modulation Targeting T Cell Dysfunction in Complex Regional Pain Syndrome
Jason Wickman – Senior Pharmacology & Physiology Graduate Student (Ajit lab), Drexel University College of Medicine
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November 17
Dynamic Control of Neuronal Firing by KATP Channels
Ricardo M. Leão, PhD – Associate Professor, Department of Physiology, University of São Paulo School of Medicine, Ribeirão Preto, São Paulo, Brazil
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December 5
HIV-Infected Humanized Mice Reproduce Aspects of Neurologic Dysfunction and Other Comorbidities
Amanda Brown, PhD – Associate Professor, Department of Neurology & Neuroscience; Director, Johns Hopkins Internship in Brain Sciences; Co-Director, Johns Hopkins Center for the Advancement of HIV Neurotherapeutics, Johns Hopkins University School of Medicine
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Download Full Retreat Agenda
The Pharmacology and Physiology Department Retreat was held December 1-2, 2022, at The Study at University City, 20 S. 33rd St., Philadelphia, PA 19104.
The two-day event featured:
- Research talks from faculty and trainees
- Drexel applied innovation
- TRaCES initiative and core facility
- MOTOR center (new)
- Education and career panels
- Breakout sessions for trainees and faculty
- Elevator talks in small groups
- Keynote speaker - Dr. Nate Smith, Partner @ Maple Health Group, LLC
Retreat Awards
Student Awards
Best Research Talks: Julia Farnan & Amber Jones
Best Elevator Talks: Katelyn Reeb & Chun-Ta Ho
Fastest Elevator Talk: Anna Zhang
Best Question: Gabriele Romano, PhD
Don’t Say the Word Game Champions: Clara Xu & Christina Besada
Benjamin Weiss Scholar Award: Kathleen Bryant
Mary Hoffman Shaw Travel Awards: Xuan Luo, Rhea Temmermand & Deepa Reddy
Chair’s Awards
Exemplary Citizen Award: Jonathan Snyder
Outstanding Service Award: Liz Kopen
Faculty Service Award: Zachary Klase, PhD
Highest impact factor publication: Priscila Sato, PhD
Success in collaborative efforts: Peter Gaskill, PhD & Zachary Klase, PhD
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September 20
Keisa W. Mathis, PhD – Associate Professor, Physiology and Anatomy, School of Biomedical Sciences, The University of North Texas Health Science Center at Fort Worth
Neuroimmune Communication in Health, Hypertension and Renal Inflammatory Diseases
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October 11
Johannes C. M. Schlachetzki, MD – Assistant Project Scientist, Department of Cellular and Molecular Medicine, University of California San Diego
Transcriptional and Epigenetic Regulation of Microglia in Neurodegenerative Diseases
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October 18
Lucas M. Cheadle, PhD – Assistant Professor, Neuroscience Program Area, Cold Spring Harbor Laboratory
More than Myelin: How Oligodendrocyte Precursor Cells Sculpt Circuits in the Developing Brain
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October 19
Lucas M. Cheadle, PhD – Assistant Professor, Neuroscience Program Area, Cold Spring Harbor Laboratory
Trainee Roundtable Discussion: Diversifying the Biomedical Sciences
Hosted by the Department of Pharmacology & Physiology and the Biomedical Graduate Students for Diversity
1:00 p.m., NCB room 8312
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November 1
David J. Clark, MD, PhD – Professor and Vice-Chair of Academic Affairs, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University; Chair, Board of Directors, Palo Alto Veterans Institute for Research
The Contributions of Autoimmunity to Chronic Pain
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November 8
David L. Bartlett, MD – System Chair, Allegheny Health Network (AHN) Cancer Institute, Allegheny General Hospital
Translational Research for Peritoneal Tumors
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November 29
Lori Knackstedt, PhD – Associate Professor, Department of Psychology, University of Florida
Drug Addiction and Glutamate Homeostasis in the Nucleus Accumbens
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December 13
Anjali M. Rajadhyaksha, PhD – Professor of Neuroscience in Pediatrics; Associate Dean of Program Development, Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medical College
Learning to Forget: Could Neuropsychiatric Risk Gene, CACNA1C, Underlie Individual Susceptibility to Addiction?
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January 31
Julia Farnan – Senior Pharmacology & Physiology Graduate Student (Jackson lab), Drexel University College of Medicine
Astrocyte Secreted Factors Activate Neural Development Programs in Melanoma Brain Metastasis
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February 7
Frederick “Chris” Bennett, MD – Assistant Professor, Department of Psychiatry, University of Pennsylvania
Brain Macrophage Transplantation for Research and Therapy Development
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March 7
Pablo E. Castillo, MD, PhD – Harold and Muriel Block Chair, Professor, Dominick P. Purpura Department of Neuroscience, Department of Psychiatry & Behavioral Sciences, Albert Einstein College of Medicine
Long-term Presynaptic Plasticity: Novel Functions and Mechanisms
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March 14
Kathleen R. Cho, MD – Peter A. Ward Professor of Pathology, Vice Chair for Academic Affairs, Director, Gynecologic Pathology, Interim Director, Division of Education Programs, Professor of Internal Medicine, Department of Pathology, University of Michigan
Mouse Models of “Ovarian” Cancer: Progress, Problems and Platforms for Testing Prevention Strategies
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March 28 (postponed until Fall 2023)
Jason J. Paris, PhD – Research Associate Professor, Department of BioMolecular Sciences, University of Mississippi
Natural Products Drug Discovery for NeuroHIV
April 4
Jonathan Snyder – Senior Pharmacology & Physiology Graduate Student (Sato lab), Drexel University College of Medicine
Pancreatic Islet GRK2 Regulates Hormone Secretion and Glycemic Control by Regulating Metabolism and GPCR Sensitivity
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April 25
Mariana Cherner, PhD – Professor of Psychiatry, Director, Interdisciplinary Research Fellowship in NeuroHIV, HIV Neurobehavioral Research Program, University of California San Diego
Contributions of substance use to neurocognitive functioning in HIV
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May 2
Geoffroy Laumet, PhD – Assistant Professor, Department of Physiology, College of Natural Science, Michigan State University
Peripheral interleukin-10-producing monocytes contribute to sex differences in pain resolution in mice and humans
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June 27
Katelyn Reeb – Senior Pharmacology & Physiology Graduate Student (A. Mortensen lab), Drexel University College of Medicine
Determining the mechanism and clinical potential of positive allosteric modulation of glutamate transporters
July 11
Maria Cavallo – Senior Pharmacology & Physiology Graduate Student (Hartsough lab), Drexel University College of Medicine
Exploiting pyroptosis in melanoma brain metastases
July 25
Qiaowei Xie – Senior Pharmacology & Physiology Graduate Student (Barker lab), Drexel University College of Medicine
The impact of EcoHIV on cocaine-related behaviors
August 1
Christina Besada – Senior Pharmacology & Physiology Graduate Student (O. Mortensen lab), Drexel University College of Medicine
Bidirectional ERK 1/2 modulation in dopaminergic neurons regulates DAT trafficking and function
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June 16, 2022
12 – 1 p.m.
Research Highlights:
- David L. Bartlett, MD
System Chair, Allegheny Health Network Cancer Center
Professor of Surgery, Drexel University College of Medicine
- Linwood Haith, MD
Chief, Burn Surgery, Nathan Speare Regional Burn Treatment Center, Chester-Crozer Medical Center
Associate Professor of Surgery, Drexel University College of Medicine
- Garth Ehrlich, PhD
Professor, Department of Microbiology & Immunology and Department of Otolaryngology
Executive Director, Genomics Core, Drexel University College of Medicine
Professional Development:
Strategies for obtaining NRSA pre-doctoral fellowships from the NIH
- Jacqueline Barker, PhD
Associate Professor, Department of Pharmacology & Physiology, Drexel University College of Medicine
- Moderated by Seena Ajit, PhD
Associate Professor, Department of Pharmacology & Physiology, Drexel University College of Medicine
Please contact Danielle Zimmerman (dnz29@drexel.edu) for the Zoom link.
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September 21
Maria Cecelia Marcondes, PhD – Associate Professor, Department of Neuroimmunology, San Diego Biomedical Research Institute (SDBRI)
Methamphetamine, Dopamine and Breaching Latency
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September 28
Angel Lin – Senior Pharm/Phys Student, Klase Lab – Drexel University College of Medicine
RUNX1 and its Potential Involvement in the Establishment and Maintenance of HIV Latency
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October 12
Jessica Loweth, PhD – Assistant Professor, Department of Cell Biology & Neuroscience, Rowan University College of Osteopathic Medicine, Stratford, NJ
Investigating Neuroadaptations in the Basolateral Amygdala Underlying Sex Differences In Cue-Induced Cocaine Craving
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October 19
Kathleen G. Bryant – Senior Pharm/Phys Student, Barker Lab – Drexel University College of Medicine
Low Dose Ethanol Effects on Reward Motivation
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October 26
Christopher M. Norris, PhD – Professor, Department of Pharmacology and Nutritional Sciences, Sylvia Mansbach Chair in Alzheimer’s Research, Associate Director of Research & Faculty Advancement, Sanders-Brown Center on Aging Professor, University of Kentucky College of Medicine
Targeting Reactive Astrocytes in Alzheimer’s Disease and Related Disorders
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November 9
Jared W. Young, PhD – Professor, Department of Psychiatry, University of California San Diego, Co-Director, Neuropsychopharmacology Unit, VA Research, San Diego, CA
Determining the Impact of HIV-Relevant Proteins & Substance Use that Contribute to Cognitive and Behavioral Dysfunction Using Rodent Models
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January 11, 2022
Jared Luchetta, Senior Pharm/Phys Student, Meucci Lab, Drexel University College of Medicine
Examining the Role of Inhibitory Neurons in CXCL12’s Effect on Neuronal Network Activity and Structural Plasticity
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January 11
Jared Luchetta – Senior Pharm/Phys Student, Meucci Lab, Drexel University College of Medicine
Examining the Role of Inhibitory Neurons in CXCL12’s Effect on Neuronal Network Activity and Structural Plasticity
January 25
Louise Risher, PhD – Assistant Professor, Department of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, Huntington, W.Va.
Hippocampal Dysregulation Following Adolescent Binge Drinking: A Role for the Tripartite Synapse
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February 1
Krzysztof Kaminski, PhD – Professor, Department of Pharmaceutical Chemistry, Vice Chairman of Pharmaceutical Sciences, Jagiellionian University Medical College, Krakow, Poland
Modified Amino Acid Derivatives as Candidates for Novel and Broad-Spectrum Antiseizure Drugs
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February 15
Julia Farnan – Senior Pharm/Phys Student, Jackson Lab, Drexel University College of Medicine
Investigating Astrocyte Reactivity in Melanoma Brain Metastases
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February 22
Rebecca Veenhuis, PhD – Assistant Professor, Department of Molecular & Comparative Pathobiology, Retrovirus Laboratory, Johns Hopkins University School of Medicine
Elucidating the SIV and HIV Latent Cellular Reservoirs
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March 8
Lindsay K. Festa, PhD – Postdoctoral Researcher, Department of Pathology, University of Pennsylvania and Department of Neurology, Children’s Hospital of Philadelphia
Lysosomal De-Acidification Inhibits Oligodendrocyte Maturation: Implications for HIV-associated Neurocognitive Disorders
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March 29
Peter M. Grace, PhD – Assistant Professor, Rita Allen Foundation Scholar, Department of Symptom Research, Neuroimmunology Laboratories, University of Texas MD Anderson Cancer Center
Activating Endogenous Antioxidant Signaling to Relieve Neuropathic Pain
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April 12
Daniel P. Kelly, MD – Willard & Rhoda Ware Professor of Diabetes and Metabolic Diseases, Department of Medicine, University of Pennsylvania Perelman School of Medicine
Targeting Metabolic Circuits in the Failing Heart
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April 19
Frank Maldarelli, MD, PhD – Senior Investigator, HIV Dynamics and Replication Program; Head, Clinical Retrovirology Section, National Cancer Institute Center for Cancer Research
HIV Persistence During Antiretroviral Therapy in Anatomic Compartments: A View From the Fridge
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April 26
Alana L. Welm, PhD – Professor, Department of Oncological Sciences, University of Utah; Director of Basic Science, Huntsman Comprehensive Cancer Center, Huntsman Cancer Institute
Patient-Derived Models of Breast Cancer for Pre-Clinical Research and Functional Precision Medicine
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May 10
Gonzalo Torres, PhD – Professor and Chair, Department of Molecular, Cellular & Biomedical Sciences, CUNY School of Medicine
G Protein Regulation of the Dopamine Transporter and the Actions of Amphetamine
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May 17
Eva Hernando-Monge, PhD – Professor, Department of Pathology, Assistant Dean for Research Integration, NYU Grossman School of Medicine, NYU Langone Health
Melanoma Brain Metastasis: An Unexpected Connection to Neurodegeneration
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May 31
Mitchell A. Nothem, PhD – Barker Lab, Drexel University College of Medicine
The Effect of Ethanol on Pain-Related Behavior and Reward Seeking in a Model of Chronic Pain
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September 22
Jay McLaughlin, PhD – Professor, Department of Pharmacodynamics, University of Florida College of Pharmacy
Evaluating contributions of HIV-1 Tat protein to neurodysfunction and psychiatric deficits associated with neuroAIDS
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October 6
Laura Giacometti, PhD – Barker Lab, Drexel University College of Medicine
Astrocytic regulation of reward seeking in ethanol-dependent mice
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October 13
Stacia Lewandowski – Senior Pharm/Phys Student, O. Mortensen Lab, Drexel University College of Medicine
In Vivo Studies of the Role of ERK 1/2 Phosphatase MKP3 in Dopaminergic Neurons on Cocaine-Associated Behavior, Dopamine Signaling and Gene Expression
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October 20
Jesse Schank, PhD – Associate Professor of Neuroscience, Physiology & Pharmacology, University of Georgia
The Role of the Neurokinin-1 Receptor in Stress-Induced Drug and Alcohol Seeking
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October 27
Shaili Aggarwal, PhD – O. Mortensen Lab, Drexel University College of Medicine
Allosteric Modulation of the Dopamine Transporter: A New Opportunity in Developing Unique and Promising Therapeutics for Cocaine Abuse Disorder
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November 10
Harald Sontheimer, PhD – I. D. Wilson Chair and Professor, Founding Executive Director, Virginia Tech School of Neurosciences, Commonwealth Eminent Scholar in Cancer Research; Director, Center for Glial Biology in Health, Disease & Cancer, Virginia Tech Fralin Biomedical Research Institute
Glial Neuronal Vascular Interactions in Neurological Disease
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November 17
Zachary Campbell, PhD – Assistant Professor, Department of Biological Sciences, The University of Texas at Dallas
RNA Control in Pain
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December 8
Emily Nickoloff-Bybel – Senior Pharm/Phys Student, Gaskill Lab, Drexel University College of Medicine
Signaling mechanisms underlying dopamine-mediated increases in HIV entry
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January 12
Stephanie Matt, PhD – Postdoctoral Fellow, Gaskill Lab, Drexel University College of Medicine
Dopamine-mediated mechanisms regulating neuroinflammation and neuroHIV in myeloid cells
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January 19
Claudia Capparelli, PhD – Research Assistant Professor, Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University
Tumor heterogeneity in melanoma, resistance and therapeutic opportunities
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January 26
Anthony DiNatale – Senior Pharm/Phys student, Fatatis Lab, Drexel University College of Medicine
Molecular characterization of critical mediators of metastatic disease
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February 2
Brandon Henderson, PhD – Assistant Professor, Neuroscience and Developmental Biology Research Center Coordinator, Department of Biomedical Sciences, Marshall University
Nicotine flavorants and formulations unique to vaping alter dopamine neurons and impact reward and reinforcement
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February 16
Richa Gupta, PhD – Research Associate, Ajit Lab, Drexel University College of Medicine
Dual and opposing roles of long non-coding RNA XIST in acute and chronic inflammation
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February 23
Jun Zhu, MD, PhD – Professor, Department of Drug Discovery and Biomedical Sciences, South Carolina College of Pharmacy
Unlocking a mystery for neuroHIV: the impact of monoamine transporter on HIV-1 tat regulation of dopamine transmission
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March 16
Francesco Petrelli, PhD, Research Associate, Department of Biochemical Sciences, Laboratory of Stem Cell Metabolism, University of Lausanne (Switzerland)
How Mitochondrial Metabolism Controls Glial Cell Behavior
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March 23
Ramanpreet Kaur, PhD – Postdoctoral Fellow, Fatatis Lab, Drexel University College of Medicine
The Role of the CX3CR1-FKN Axis in Tumor Initiation and Metastatic Progression
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April 6
Steven P. Jones, PhD – Professor, Director, Diabetes & Obesity Center, Department of Medicine, Division of Environmental Medicine, University of Louisville
Metabolic Regulation of Tissue Structure and Function: The Heart of the Matter
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April 20
Keiran Smalley, PhD – Professor, Director of the Melanoma and Skin Cancers Center of Excellence, Professor and Donald A. Adam Chair in Melanoma Research, Senior Member, Department of Tumor Biology, Moffitt Cancer Center
Multi-Omics Analysis of the Microenvironment Gives New Insights in Brain Metastasis Progression and Treatment
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May 4
Zhucheng Lin – Senior Pharm/Phys Student, Ajit Lab, Drexel University College of Medicine
The Role of Small Extracellular Vesicles in Neuropathic Pain
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May 11
Michael Burton, PhD – Assistant Professor, Department of Neuroscience, Neuroimmunology and Behavior Research Group, University of Texas at Dallas
Investigating Cell-Specific Mechanisms Driving Sex Differences in the Development of Inflammatory Pain
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May 25
Lena Al-Harthi, PhD – The Thomas J. Coogan Sr., MD, Chair of Immunology, Department of Microbial Pathogens and Immunity, Director of Rush Initiative to Maximize Student Development (Rush-IMSD), Rush Medical College
Topic: The Brain, the Other Glia, and HIV
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June 8
Gabriele Romano, PhD – Postdoctoral Fellow, Department of Translational Molecular Pathology, MD Anderson Cancer Center, The University of Texas
Topic: Intrinsic and Acquired Drug Resistance in Melanoma: Bench-to-Bedside and Back Again
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Monday, September 16, 11:30 a.m.
Atom Sarkar, MD, PhD,
professor, Department of Neurosurgery, Drexel Neurosciences Institute
Human Brain Tumors: Molecules and Models
October 8
Kathryn J. Reissner, PhD, associate professor, Department of Psychology & Neuroscience, University of North Carolina at Chapel Hill
A Role for Astrocytes in the Development of Cocaine Addiction
October 15
Allison M. Andrews, PhD, assistant professor, Department of Pathology, Temple University
Brain Endothelial Extracellular Vesicles (EVs): Biomarkers, Immune Regulators and Pathological Contributors
October 29
John D. Imig, PhD, professor, Department of Pharmacology & Toxicology, Medical College of Wisconsin
Eicosanoid Drugs: Prospects for Treating Human Diseases
Friday, November 15, 1 p.m.
Jeffery D. Molkentin, PhD, professor, Division of Molecular & Cardiovascular Biology, Cincinnati Children’s Hospital Medical Center
Can Adult Stem Cells Really Regenerate the Damaged Heart?
November 26
Ashley M. Kopec, PhD, assistant professor, Neuroscience & Experimental Therapeutics, Albany Medical College
Sex-Specific Immune Mechanisms Guide
Adolescent Brain and Behavioral Development
December 3
Srinivas Malladi, PhD, assistant professor, Department of Pathology, UT Southwestern Medical Center
Metastatic Latency – A Veiled Threat
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Please note: All Spring 2020 seminars have been postponed.
Unless otherwise noted, all seminars take place in the New College Building, 245 N. 15th Street, in the John A. Harvey Conference Room (Room 8312) at 11 a.m.
January 14
Luciano D’Adamio, MD, PhD, Rutgers University
BAD-Glu and Neurodegeneration
January 21
Michael Henderson, PhD, research associate, Center for Neurodegenerative Disease Research, University of Pennsylvania
Understanding and Developing Therapeutics for Neurodegenerative Diseases in Preclinical Models
January 28
Davide Trotti, PhD, Jefferson Weinberg ALS Center/Sidney Kimmel Medical College
Non-cell Autonomous Pathways of Neurodegeneration in Amyotrophic Lateral Sclerosis: An Unconventional Role for the Astroglia Glutamate Transporter EAAT2
Wednesday, February 12, 3 p.m. (note different time)
Conor Liston, MD, PhD, Weil Cornell Medicine-Feil Family Brain & Mind Research Institute
Prefrontal Cortical Circuit Dysfunction in Depression-Like Behavioral States
March 3
Mitchell Lazar, MD, PhD, University of Pennsylvania School of Medicine
Transcriptional Regulation of Circadian Rhythms and Metabolism
POSTPONED: March 17
Gonzalo Torres, PhD, CUNY School of Medicine
G Protein Regulation of the Dopamine Transporter and the Actions of Amphetamine
POSTPONED: March 24
David Clark, MD, PhD, Stanford University & VA Palo Alto Health Care System
Persistent Postoperative Pain: Mechanisms and Modulators
POSTPONED: March 31
Jesse Schank, PhD, University of Georgia
The Role of the Neurokinin-1 Receptor in Stress-Induced Drug and Alcohol Seeking
POSTPONED: April 14
Douglas Tilley, PhD, Temple University School of Medicine
Epidermal Growth Factor Receptor Regulation of Cardiac Health and Disease
POSTPONED: May 5
Jun Zhu, PhD, University of South Carolina College of Pharmacy
Unlocking a Mystery for NeuroHIV: The Impact of Monoamine Transporter on HIV-1 Tat Regulation of Dopamine Transmission
POSTPONED: May 12
Harald Sontheimer, PhD, Virginia Tech
TBA
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September 18
Dr. Yesim Eralp,
Istanbul University
Advances in Personalized Medicine and Immunotherapy in Oncology
October 9
Dr. Jacqueline Barker, Drexel University
Regulation of Flexible Behavior by Glutamatergic Circuits
October 16
Dr. Heidi Ford, University of Colorado
Tumor Heterogeneity, EMT and Metastasis
November 27
Dr. Tricia Burdo, Temple University
HIV-Associated Atherosclerosis and Myocardial Fibrosis
December 4
Dr. Eduardo Candelario-Jalil
University of Florida-Gainesville
Neurovascular Protection by Adropin in Experimental Ischemic Stroke
January 29
Dr. Priscila Sato,
Drexel University
GRK2 in Mediating Metabolism
February 5
Dr. Ashani Weeraratna,
The Wistar Institute
A Wrinkle in TiME: How the Aged TME Affects Tumor Progression
March 5
Dr. Jonathan Geiger, University of North Dakota
An "Iron-ic" Story About Endolysosomes and HAND Pathogenesis
March 26
Dr. Jonathan Javitch,
Columbia University
A Tale of Two Substrates: an Allosteric Mechanism for Neurotransmitter: Sodium Symporters
April 2
Dr. Stanley Thayer,
University of Minnesota
Adaptations to HIV Neurotoxins Change the Pharmacology of Synapses
April 30
Dr. Levi Beverly,
University of St. Louis
Studying Mechanisms of Cancer Progression, Therapeutic Response and Detrimental Therapy-Related Side Effects
May 7
Dr. Cagla Akay Espinoza,
University of Pennsylvania
Unintended Consequences: Adverse Effects of Antiretroviral Compounds in the CNS
May 21
Dr. Matt Wanat, University of Texas, San Antonio
Mesolimbic Dopamine Circuits in Positive and Negative Reinforcement
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September 19
Norman J. Haughey, PhD, Johns Hopkins University School of Medicine
Stimulus-Dependent Cargo Inclusion of Astrocyte Shed Extracellular Vesicles Regulates the Target's Response
October 10
Pietro P. Sanna, MD, The Scripps Research Institute
Lessons From the Transcriptome: Gene Network Dysregulations in NeuroAIDS and Substance Abuse
October 16
Priscila Sato, PhD, Temple University School of Medicine
Faculty Candidate Seminar: From Ion Channels to Cardiac GPCR-Signaling: In Search of New Therapeutic Targets
Monday, October 30 at 3 p.m.
Dr. Shubha Gururaja Rao, Drexel University
Role of Mitochondrial Structure and Function in Cell Physiology
December 5
Dr. Kevin Foskett, University of Pennsylvania
Molecular Mechanisms and Physiological Roles of Ca2+ Crosstalk Between ER and Mitochondria
January 9
Dr. Peter Gaskill, Drexel University
Mechanisms of Dopamine Mediated Increase in HIV Infection of Macrophages
February 20
Dr. Andreia Mortensen, Drexel University
Positive Allosteric Modulation of Glutamate Transporters for CNS Disorders
March 6
Please note that Dr. Levine's seminar has been rescheduled for May 22.
Dr. Jon Levine, University of California-San Francisco
Persistent, Chronic and Analgesic-Induced Pain
April 3
Dr. Sergi Ferre, National Institute on Drug Abuse
Pre-coupling of Receptor Oligomers and Signaling Molecules: Challenging Classical Pharmacology
May 1
Dr. Qiufu Ma, Harvard University
Mapping Spinal Circuits and Revisiting "Pain” Measurement in Mice
May 15
Dr. Devasena Ponnalagu, Drexel University
Mitochondrial Chloride Channels: A Newbie
in the Family
May 22
Dr. Jon Levine, University of California-San Francisco
Persistent, Chronic and Analgesic-Induced Pain
May 29
Dr. Paul M. Mathews, NYU School of Medicine, Nathan Kline Institute/Center for Cognitive Neurology
Regulation of the Endosomal Pathway by Amyloid Precursor Protein Fragments: Implication for Alzheimer’s Disease and Neurodegeneration
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October 18
Dr. Joan Berman, Albert Einstein College of Medicine
Mechanisms of Neuroinflammation and Toxicity: Critical Roles in NeuroAids
November 8
Dr. Habibeh Khoshbouei, University of Florida
Sigma-1 Receptor Regulation of Dopamine Neurotransmission: Beyond the Surface Membrane
November 29
Dr. Fadi Akar, Mount Sinai School of Medicine
Arrhythmia Mechanisms and Therapies in Large Animal Models of Advanced Heart Failure
January 17
Dr. Dennis Kolson, University of Pennsylvania
Brain Heme Oxygenase -1 Deficiency, Oxidative Stress and HIV-Associated Neuro Cognitive Disorders: Potential Therapeutic Targeting
January 24
Dr. Daniel Marenda, Drexel University
Flying in the Face of Disease: Using Drosophila to Identify Drugs for Alzheimer's Disease
February 7
Dr. Phil Wedegaertner, Thomas Jefferson University
Gβγ Regulation of Golgi Function and Structure
February 9
Faculty Candidate Seminar: Bradley K. Taylor, PhD, Department of Physiology, University of Kentucky
Trauma Establishes an Opponent Process of Latent Pain Sensitization and Mu Opioid Receptor Constitutive Activity
February 21
Dr. Elizabeth Heller, University of Pennsylvania
Elucidating the Function of Epigenetic Remodeling in Reward Pathology
March 21
Dr. Mohamed Trebak, Penn State University College of Medicine
STIM-ORAI Mediated Ca2+ Signaling in Disease: Lessons from Smooth Muscle
March 28
Dr. Marco Cosentino, University of Insubria, Italy
Adrenergic and Dopaminergic Pathways in the Nervous and Immune System as Opportunities for Novel Therapeutics
April 11
Dr. Yuan-Xiang Tao, Rutgers-New Jersey Medical School
Epigenetic Mechanisms of Neuropathic Pain
April 18
Dr. Ru-Rong Ji, Duke University School of Medicine
Pain and Autism: Peripheral Regulation
April 19
Faculty Candidate Seminar: Jacqueline M. Barker, PhD, postdoctoral fellow, Department of Neuroscience, Medical University of South Carolina
Arbitration Between Actions and Habits by the Prefrontal Cortex
May 2
Dr. Jean-Pierre Vilardaga, University of Pittsburgh
Endosomal and Mitochondrial GPCR Signaling
May 9
Faculty Candidate Seminar: Giulio Agnetti, PhD, FAHA, assistant professor, Department of Medicine/Division of Cardiology; director, Center for Research on Cardiac Intermediate Filaments (CRCIF), Johns Hopkins University School of Medicine
What Do Intermediate Filaments Really Do? A Lesson from the Heart
June 6
Dr. Dionna Williams, Johns Hopkins
Johns Hopkins
June 14 (Wednesday)
Dr. Joseph Baker, The College of New Jersey
Biomolecules in Motion: Molecular Modeling and Simulation of Biomolecular Systems
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