Hereditary Spastic Paraplegia: gain-of-function mechanisms revealed by new transgenic mouse
Qiang L, Piermarini E, Muralidharan H, Yu W, Leo L, Hennessy LE, Fernandes S, Connors T, Yates PL, Swift M, Zholudeva LV, Lane MA, Morfini G, Alexander GM, Heiman-Patterson TD, Baas PW
Hum Mol Genet. 2018 Dec 6. doi: 10.1093/hmg/ddy419. [Epub ahead of print] PMID: 30520996

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Face-selective regions differ in their ability to classify facial expressions
Zhang H, Japee S, Nolan R, Chu C, Liu N, Ungerleider LG
Neuroimage. 2016 Apr 15;130:77-90. doi: 10.1016/j.neuroimage.2016.01.045. Epub 2016 Jan 28. PubMed PMID: 26826513; PubMed Central PMCID: PMC4808360

The role of catecholamines in HIV neuropathogenesis
Nolan R, Gaskill PJ
Brain Res.2019 Jan 1;1702:54-73. doi: 10.1016/j.brainres.2018.04.030. Epub 2018 Apr 27. PubMed PMID: 29705605; PubMed Central PMCID: PMC6204123.Med Central PMCID: PMC4808360.

Role of Macrophage Dopamine Receptors in Mediating Cytokine Production: Implications for Neuroinflammation in the Context of HIV-Associated Neurocognitive Disorders
Nolan RA, Muir R, Runner K, Haddad EK, Gaskill PJ
J Neuroimmune Pharmacol.2019 Mar;14(1):134-156. doi: 10.1007/s11481-018-9825-2. Epub 2018 Dec 5. PubMed PMID: 30519866; PubMed Central PMCID: PMC6391172

Dopamine increases HIV entry into macrophages by increasing calcium release via an alternative signaling pathway
Nickoloff-Bybel, E., Mackie, P., Runner, K., Nolan, R., Khoshbouei, H., Gaskill, P.J.
Brain Behavior and Immunity: Submitted Jan 2019, under revision.

Dopamine transporter in human macrophages
Mackie P, Gopinath A, Lebowitz J, Saadatpour S, Montas D, Nolan R, Ramirez-Zamora A, Doty A, Gaskill PJ, Streit W, Okun M, Khoshbouei H
Journal of Biological Chemistry: Submitted Feb 2019, under revision.

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Face-selective regions differ in their ability to classify facial expressions
Zhang H, Japee S, Nolan R, Chu C, Liu N, Ungerleider LG
Neuroimage. 2016 Apr 15;130:77-90. doi: 10.1016/j.neuroimage.2016.01.045. Epub 2016 Jan 28. PubMed PMID: 26826513; PubMed Central PMCID: PMC4808360

The role of catecholamines in HIV neuropathogenesis
Nolan R, Gaskill PJ
Brain Res.2019 Jan 1;1702:54-73. doi: 10.1016/j.brainres.2018.04.030. Epub 2018 Apr 27. PubMed PMID: 29705605; PubMed Central PMCID: PMC6204123.Med Central PMCID: PMC4808360.

Role of Macrophage Dopamine Receptors in Mediating Cytokine Production: Implications for Neuroinflammation in the Context of HIV-Associated Neurocognitive Disorders
Nolan RA, Muir R, Runner K, Haddad EK, Gaskill PJ
J Neuroimmune Pharmacol.2019 Mar;14(1):134-156. doi: 10.1007/s11481-018-9825-2. Epub 2018 Dec 5. PubMed PMID: 30519866; PubMed Central PMCID: PMC6391172

Dopamine increases HIV entry into macrophages by increasing calcium release via an alternative signaling pathway
Nickoloff-Bybel E, Mackie P, Runner K, Nolan R, Khoshbouei H, Gaskill PJ
Brain Behavior and Immunity: Submitted Jan 2019, under revision.

Dopamine transporter in human macrophages
Mackie P, Gopinath A, Lebowitz J, Saadatpour S, Montas D, Nolan R, Ramirez-Zamora A, Doty A, Gaskill PJ, Streit W, Okun M, Khoshbouei H
Journal of Biological Chemistry: Submitted Feb 2019, under revision.

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Development Towards a Prophylactic Hepatitis C Virus Vaccine
Latimer BP, Gary EN, Kutzler MA
Current Immunol Revs. 2016.

A Little Help From the Follicles: Understanding the Germinal Center Response to Human Immunodeficiency Virus 1 Infection and Prophylactic Vaccines
Gary EN, Kutzler MA
Clinical medicine insights. Pathology, 10. 2017.

Bifunctional Chimera That Coordinately Targets HIV-1 Env gp120 and Host Cell CCR5 Co-receptor at the Virus-Cell Interface
Rashad A, Song L, Holmes A, Acharya K, Zhang S, Wang Z, Gary EN, Xie X, Pirrone V, Kutzler M, Long Y, Chaiken I
J. Med. Chemistry, ;61 (11): 5020-5033, 2018. DOI: 10.1021/acs.jmedchem.8b00477. PMCID: PMC6349035

Defensive Driving: Targeting vaccine induced responses to the mucosa with chemokine adjuvants
Gary EN, Kutzler MA
Journal of Immunol. Research. Dec 2018. https://doi.org/10.1155/2018/3734207

A Synthetic HCV Genotype 1a/1b Consensus DNA Vaccine Elicits Functional, Long-Lived Memory T cells in heparo
Latimer BP, Gary EN, Baliban SM, Yan J, Couto LB, High K, Sardesai NY, Jacobson J, Weiner DB, Kutzler MA
Under review.

Co-delivery of mucosa-associated epithelial chemokine (MEC/CCL28) enhances anti-HIV-1 mucosal responses in the context of DNA vaccination
Gary EN, Kathuria N, Bernui ME, Sardesai NE, Weiner DB, Kutzler MA
In preparation.

Adenosine deaminase (ADA-1) improves follicular helper T cell function and enhances HIV-specific antibodies in a DNA/protein co-immunization
Gary E, O’Connor M, Chakhtoura M, Kutzler M, Haigwood L, Haddad E
In preparation

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Strong HCV NS3/4a, NS4b, NS5a, NS5b-specific cellular immune responses induced in Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine
Latimer BR, Toporovski J, Yan P, Pankhong MP, Morrow AS, Khan NY, Sardesai SL, Welles JM, Jacobson DB, Weiner, Kutzler MA
Hum Vaccin Immunother. Jun 20;10(8). 2014

An Optimized, Synthetic DNA Vaccine Encoding the Toxin A/Toxin B RBDs of Clostridium difficile Induces Protective Antibody Responses In Vivo
Baliban SM, Michael A, Shammassian B, Mudakha S, Khan AS, Cocklin S, Zetner I, Latimer BP, Bouillaut L, Hunter M, Marx P, Sardesai NY, Welles SL, Jacobson JM, Weiner DB, Kutzler MA
Infect Immun. Oct;82(10):4080-91. 2014

Developments towards a prophylactic hepatitis C virus vaccine
Latimer BP, Kutzler MA
Current Immunology Reviews 12(2): 83-97. 2015

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A role for microRNA-155 modulation in the anti-HIV-1 effects of Toll-like receptor 3 stimulation in macrophages
Swaminathan G, Rossi F, Sierra LJ, Gupta A, Navas-Martín S, Martín-García J
PLoS Pathogens, 8, e1002937. 2012

Antiviral breadth and combination potential of peptide triazole HIV-1 entry inhibitors
McFadden K, Fletcher P, Rossi F, Kantharaju F, Umashankara M, Pirrone V, Rajagopal S, Gopi H, Krebs FC, Martín-García J, Shattock RJ, Chaiken IM
Antimicrobial Agents and Chemotherapy, 56, 1073-1080. 2012

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Fate of Microglia during HIV-1 Infection: From Activation to Senescence?
Chen NC, Partridge AT, Sell C, Torres C, Martín-García J
Glia, 65, 431-446. 2017

Induction of a Senescence-Like Phenotype in Cultured Human Fetal Microglia During HIV-1 Infection
Chen NC, Partridge AT, Tuzer F, Cohen J, Nacarelli T, Navas-Martín S, Sell C, Torres C, Martín-García J
Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 73, 1187-1196. 2018

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Disruption of neuronal CXCR4 function by opioids: preliminary evidence of Ferritin Heavy Chain as potential etiological agent in neuroAIDS
Pitcher J, Shimizu S, Burbassi S, Meucci O
Journal of Neuroimmunology (2010) 224:66-71

In vivo semi-quantitative image analysis of CXCR4 expression within human neurons
Pitcher J, Wurth R, Shimizu S, Meucci O
Methods in Molecular Biology (2013) vol 1013; pp 31-48; DOI10.1007/978-1-62703-426-53

Neuronal ferritin heavy chain and drug abuse affect HIV-associated cognitive dysfunction
Pitcher J, Abt A, Myers J, Han R, Snyder M, Graziano A, Festa L, Kutzler M, Garcia F, Gao WJ, Fisher-Smith T, Rappaport J, Meucci O
J Clin Invest. 2014 Jan 9. pii: 70090. doi: 10.1172/JCI70090.

"Role of Ferritin Heavy Chain and opiates in neuroAIDS"
Pitcher J, Shimizu S, Burbassi S, Sengupta S, Meucci O
9th Meeting of the International Society of Neurovirology, Miami (FL) June 2-7, 2009*

"Role of FHC in neuroAIDS:a systematic in vivo analysis of a novel CXCR4 regulator within the human cortex"
Pitcher J, Shimizu S, Burbassi S, Sengupta R, Meucci O
ASCI/AAP 2010 Joint Meeting April 23-25, 2010 Fairmont Hotel, Chicago, IL. *

"Ferritin heavy chain, CXCR4 and opiates in neuroAIDS: a multispectral image analysis within the human cortex"
Pitcher J, Shimizu S, Burbassi S, Meucci O
10th International Symposium on NeuroVirology & 2010 Conference on HIV in the Nervous System, Milan, Italy October 12-16*

"Increased levels of ferritin heavy chain protein in the cortical neurons of patients with a history of drug abuse"
Pitcher J, Shimizu S, Burbassi S, Meucci O
Neuroscience 2011, 41st Annual Meeting of the Society for Neuroscience, Washington DC, November 12-16*

"Alterations in Neuronal Ferritin Heavy Chain Expression by HIV Envelope Protein gp120 and Inflammatory Cytokines"
Festa L, Abt A, Pitcher J, Meucci O
11th International Symposium on NeuroVirology & 2012 Conference on HIV in the Nervous System, NYC, May 29-June 2*

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Interactions between chemokines: regulation of fractalkine/CX3CL1 homeostasis by SDF/CXCL12 in cortical neurons
Cook A, Hippensteel R, Shimizu S, Nicolai J Fatatis A, Meucci O
Journal of Biological Chemistry (2010) 285:10563-71

Regulation of ferritin heavy chain a new player in opiate-induced chemokine dysfuction
Abt Cook A, Meucci O
The Journal of Neuroimmune Pharmacology 2011; DOI 10.007/s11481-011-9278-3; PMID21465240

Neuronal ferritin heavy chain and drug abuse affect HIV-associated cognitive dysfunction
Pitcher J, Abt A, Myers J, Han R, Snyder M, Graziano A, Festa L, Kutzler M, Garcia F, Gao WJ, Fisher-Smith T, Rappaport J, Meucci O
J Clin Invest. 2014 Jan 9. pii: 70090. doi: 10.1172/JCI70090

"Effect of morphine on expression of heavy and light chain subunits of the ferritin protein complex in neurons"
Abt Cook A, Festa L, Meucci O
Neuroscience 2011, 41st Annual Meeting of the Society for Neuroscience, Washington DC, November 12-16*

"Effects of Morphine on Ferritin Subunits in Neurons, and Resulting Inhibition of CXCR4-mediated neuroprotection"
Abt A, Meucci O
11th Intl. Symposium on NeuroVirology & 2012 Conference on HIV in the Nervous System, NYC, May 29-June 2*

"Alterations in Neuronal Ferritin Heavy Chain Expression by HIV Envelope Protein gp120 and Inflammatory Cytokines"
Festa L, Abt A, Pitcher J, Meucci O
11th International Symposium on NeuroVirology & 2012 Conference on HIV in the Nervous System, NYC, May 29-June 2*

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Effects of Opiates and HIV Viral Proteins on Neurons: The Role of Ferritin Heavy Chain and a Potential for Synergism; invited review (peer-reviewed)
Festa L, Meucci O
Current HIV Research, 10(5):453-62 (2012) PMID: 22591369

Neuronal ferritin heavy chain and drug abuse affect HIV-associated cognitive dysfunction
Pitcher J, Abt A, Myers J, Han R, Snyder M, Graziano A, Festa L, Kutzler M, Garcia F, Gao WJ, Fisher-Smith T, Rappaport J, Meucci O
J Clin Invest. 2014 Jan 9. pii: 70090. doi: 10.1172/JCI70090. [Epub ahead of print]; PMID: 24401274

Induction of interleukin-1 beta by HIV-1 viral proteins leads to increased levels of neuronal ferritin heavy chain, synaptic injury, and deficits in flexible attention
Festa L, Gutoskey CJ, Graziano A, Waterhouse BD, Meucci O
The Journal of Neuroscience (2015) Jul 22; 35(29):10550-61. doi: 10.1523/JNEUROSCI.4403-14.2015.PMID: 26203149

"Alterations in Neuronal Ferritin Heavy Chain Expression by HIV Envelope Protein gp120 and Inflammatory Cytokines"
Festa L, Abt A, Pitcher J, Meucci O
11th International Symposium on NeuroVirology & 2012 Conference on HIV in the Nervous System, NYC, May 29-June 2*

"Involvement of Glia and Cytokines in HIV-Induced Changes of Ferritin Heavy Chain Protein Expression in Cortical Neurons"
Festa L, Meucci O
Society on NeuroImmune Pharmacology, 19th Annual Conference, San Juan, Puerto Rico, April 3-6, 2013*

"Proinflammatory cytokines and gp120 may contribute to synaptic injury through up-regulation of neuronal FHC in HIV patients"
Festa L, Gutoskey C, Duffy B, Waterhouse B, Meucci O
12th International Symposium on NeuroVirology & 2013 Conference on HIV in the Nervous System, Washington DC, Oct 29-Nov1*

"Upregulation of ferritin heavy chain by viral proteins and pro-inflammatory cytokines may contribute to synaptic injury in HIV patients"
Festa L, Meucci O
23rd Neuropharmacology Conference 2013: The Synaptic Basis of Neurodegenerative Disorders", Satellite conference of the 43rd Annual Meeting of the Society for Neuroscience, San Diego (CA), Nov. 7-8*

"Host and viral factors involved in HIV-induced synaptodendritic injury: the role of ferritin heavy chain protein"
Festa L, Meucci O
2nd International Symposium on Molecular Medicine and Infectious Disease, Philadelphia (PA), June 16-20, 2014*

"Interleukin-1 beta released by gp120 mediates upregulation of neuronal ferritin heavy chain and may contribute to synaptic injury in HIV infection"
Festa L, Meucci O
Society on NeuroImmune Pharmacology, 20th Conference, New Orleans, March 26-29, 2015*

"Synaptodendritic injury in HAND: role of IL1-beta mediated induction of the protein ferritin heavy chain in cortical neurons"
Festa L, Gutoskey G, Graziano A, Waterhouse B, Meucci O
Annual Meeting of the international Society on NeuroImmune Pharmacology, Miami, April 22-25, 2015*

"The critical role of the inflammatory cytokine interleukin-1 beta and the iron storage protein ferritin heavy chain in synaptodendritic injury during HIV infection"
Festa L, Gutoskey C, Graziano, A, Waterhouse, B, Meucci O
Society for Neuroscience Annual Meeting, October 17-21, 2015, Chicago*

"Alterations in dendritic spine density and morphology in neuroAIDS: variable susceptibility amongst brain regions in two rodent models of HAND"
Festa L, Lin C, Platt B, Floresco S, Meucci O
Society for Neuroscience Annual Meeting. November 12-17, 2016, San Diego, CA – selected as oral presentation at the nanosymposium on Inflammatory and non-inflammatory mechanisms of HAND. (invited to give talk) *

"In vivo manipulation of the CXCL12/CXCR4 signaling axis increases dendritic spine density and enhances cognitive flexibility in wild-type and HIV-Tg rats via the Rac1/PAK pathway"
Festa L, Tian Y, Platt B, Floresco S, Meucci O
Society on Neuroimmune Pharmacology Annual Meeting. March 29-April 1, 2017, Philadelphia, PA*

"The chemokine CXCL12 modulates dendritic spine density in pyramidal neurons of the medial prefrontal cortex and enhances relevant cognitive function in HIV-Tg rats"
Festa L, Platt B, Tian Y, Floresco SB, Meucci O
Cell Symposium: Neuro-immune axis: Reciprocal Regulation in Development, Health, and Disease. September 17th-19th, 2017, Sitges, Spain*

"The chemokine CXCL12 rescues dendritic spine loss and cognitive deficits in HIV-Tg rats: implications for the treatment of HAND"
Festa L, Platt B, Tian Y, Floresco SB, Meucci O
Philadelphia Wide Neurovirology and Neuroimmunology Symposium. September 28th, 2017, Philadelphia, PA*

"The chemokine CXCL12 reverses dendritic spine loss and cognitive dysfunction in the HIV-Tg rat"
Festa L, Platt B, Tian Y, Floresco SB, Meucci O
NeuroHIV in the ART Era. October 23rd-24th, 2017, Rockville, MD*

"In vivo manipulation of the CXCL12/CXCR4 signaling axis increases dendritic spine density and enhances cognitive flexibility in wild-type and HIV-Tg rats: role of the Rac1/PAK pathway and implications for neurocognitive disorders"
Festa L, Tian Y, Platt B, Floresco SB, Meucci O
Society for Neuroscience Annual Meeting. November 11th-15th, 2017, Washington, DC*

"Recovery of thin spine density is essential for rescuing cognitive function in a rodent model of HAND: role of the chemokine CXCL12 and the Rac1/PAK pathway"
Festa L, Platt B, Tian Y, Floresco SB, Meucci O
Neuroimmune Pharmacology 24th International Conference. April 10th-14th, 2018, Chicago, IL*

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Interaction between Tat and Drugs of Abuse during HIV-1 Infection and Central Nervous System Disease
Maubert M, Pirrone V, Rivera NT, Wigdahl B, Nonnemacher MR
Frontiers in Microbiology, 6:1512, 2016. PMCID: PMC4707230. DOI: 10.3389/fmicb.2015.01512.

Co-culture model consisting of human brain microvascular endothelial and peripheral blood mononuclear cells
Strazza M, Maubert M, Pirrone V, Wigdahl B, Nonnemacher MR
Journal of Neuroscience methods, 269: 39-45, 2016. DOI:10.1016/j.jneumeth.2016.05.016

Prolonged Morphine Exposure Induces Increased Firm Adhesion in an In Vitro Model of the Blood–Brain Barrier
Strazza M, Pirrone V, Wigdahl B, Dampier W, Lin W, Feng R, Maubert ME, Weksler B, Romero IA, Pierre-Olivier C, Nonnemacher MR
International Journal of Molecular Sciences, 17(6). pii: E916, 2016. PMCID: PMC4926449. DOI: 10.3390/ijms17060916

Inhibition of Blood-brain Barrier Repair as a Mechanism in HIV-1 Disease
Maubert ME, Wigdahl B, Nonnemacher MR
Frontiers in Neuroscience, 11: 228, 2017. PMCID: PMC5405129. DOI: 10.3389/fnins.2017.00228

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Defining the molecular mechanisms of HIV-1 Tat secretion: PtdIns(4,5)P2 at the epicenter
Mele AR, Marino J, Chen K, Pirrone V, Janetopoulos C, Wigdahl B, Klase Z, Nonnemacher MR
Traffic, Epub ahead of print. DOI: 10.1111/tra.12578. PMCID: PMC6207469. 2018

Genetic variation and function of the HIV-1 Tat protein
Spector C, Mele AR, Wigdahl B, Nonnemacher MR
Medical Microbiology and Immunology. DOI: 10.1007/s00430-019-00583-z. March 5, 2019

Investigating the distribution of HIV-1 Tat lengths present in the Drexel Medicine CARES cohort
Link RW#, Mele AR# Pirrone V, Zhong W, Kercher K, Passic S, Szep Z, Malone K, Dampier W, Wigdahl B, Nonnemacher MR
Virus Research, submitted, 2019.

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HIV excision utilizing CRSPR/cas9 technology: Attacking the proviral quasispecies in reservoirs to achieve a cure
Dampier W, Nonnemacher MR, Sullivan NT, Jacobson JM, Wigdahl B
MOJ Immunology, 1(4): 00022. doi: 10.15406/moji.2014.01.00022. PMCID: PMC4399856. 2014

Human immunodeficiency virus type 1 cellular entry and exit in the T lymphocytic and monocytic compartments: Mechanisms and target opportunities during viral disease
Aiamkitsumrit B, Sullivan NT, Nonnemacher MR, Pirrone V, Wigdahl B
Advanced Virus Research, 93: 257-311. doi: 10.1016/bs.aivir.2015.04.001. 2015

"Leukemia and Retroviral Disease"
Loarca L, Sullivan N, Pirrone V, Wigdahl B
In: Leukemias-Updates and New Insights, edited by M. Guenova and G. Balatzenko, INTECH. 2015

HIV-1 promoter single nucleotide polymorphisms (SNPs) are associated with clinical disease severity
*Nonnemacher MR, *Pirrone V, Feng R, Moldover B, Passic S, Aiamkitsumrit B, Dampier W, Wojno A, Kilareski E, Blakey B, Ku TS, Shah S, Sullivan NT, Jacobson JM, Wigdahl B
PloSOne, 11(4): e0150835. DOI: 10.1371/journal.pone.0150835. Authors contributed equally. PMCID: PMC4839606. 2016

HIV-1 Latency and Eradication: Past, Present and Future
Datta PK, Kaminski R, Hu W, Pirrone V, Sullivan NT, Nonnemacher MR, Dampier W, Wigdahl B, Khalili K
Current HIV Research, 14: 431-441. PMCID: PMC5157928. 2016

Designing broad-spectrum anti-HIV-1 gRNAs to target patient-derived variants
Dampier W, Sullivan NT, Chung C-H Mell JC, Nonnemacher MR, Wigdahl B
Science Reports, 7(1):14413. DOI: 10.1038/s41598-017-12612-z. PMCID: PMC5663707. 2017

Broad spectrum and personalized gRNAs for CRISPR/Cas9 HIV-1 therapeutics
Dampier W#, Sullivan NT#, Mell JC, Pirrone V, Ehrlich G, Cheng-Han C, Allen AG, DeSimone M, Zhong W, Kercher K, Passic S, Williams JW, Szep Z, Khalili K, Jacobson JM, Nonnemacher MR, Wigdahl B
AIDS Res Hum Retroviruses, Epub ahead of print. DOI: 10.1089/AID.2017.0274 #These authors contributed equally to this work. 2018

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Identification of essential and non-essential genes in Ambystoma tigrinum virus
Aron MM, Allen AG, Kromer M, Galvez H, Vigil B, Jancovich JK
Virus Research 217: 107-114, 2016

The Ambystoma tigrinum virus (ATV) RNase III gene modulates host PKR activation and interferon production
Allen AG, Morgans S, Smith E, Aron MM, Jancovich JK
Virology 511: 300-308, 2017

Modeling the pathology, immune response, and kinetics of HSV-1 replication in the lip scarification model
Egan KP, Allen AG, Wigdahl B, Jennings SR
Virology, 514: 124-133, 2017

Broad spectrum and personalized gRNAs for CRISPR/Cas9 HIV-1 therapeutics
Dampier W#, Sullivan NT#, Mell JC, Pirrone V, Ehrlich G, Cheng-Han C, Allen AG, DeSimone M, Zhong W, Kercher K, Passic S, Williams JW, Szep Z, Khalili K, Jacobson JM, Nonnemacher MR, Wigdahl B
AIDS Res Hum Retroviruses, 34 (11): 950-960. DOI: 10.1089/AID.2017.0274 #These authors contributed equally to this work. PMCID: PMC6238604. 2018

Gene editing of HIV-1 co-receptors to prevent and/or cure virus infection
Allen AG, Chung C-H, Atkins A, Dampier W, Khalili K, Nonnemacher MR, Wigdahl B
Frontiers in Microiology, 9: 2940. https://doi.org/10.3389/fmicb.2018.02940 PMCID: PMC6304358. 2018

Development and functional validation of a novel gRNA design pipeline for CRISPR/Cas9 mediated excision therapy of HIV-1 infected individuals
Sullivan NT, Dampier W, Chung C, Allen AG, Atkins A, Pirrone V, Homan G, Moldover B, Feng R, Passic S, Williams J, Zhong W, DeSimone M, Kercher K, Szep Z, Jacobson JM, Nonnemacher MR, Wigdahl B
| Scientific Reports, in review, 2019

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Dendritic Cells in Autoimmune Diseases and Neuroinflammatory Disorders
Manuel SL, Rahman S, Wigdahl B, Khan ZK, Jain P
Frontiers in Bioscience, 12: 4315-4335. PMID: 17485377. 2007

DC-SIGN mediates cell-free infection and transmission of human T cell leukemia virus type 1
Jain P, Manuel S, Khan ZK, Ahuja J, Wigdahl B
Journal of Virology, 83(21): 1054-1059. PMCID: PMC2772783. 2009

Presentation of HTLV-1 Tax protein by dendritic cells: the underlying mechanism of HTLV-1 associated neuroinflammatory disease
Manuel ST, Schell E, Acheampong S, Rahman ZK, Khan Z, Jain P
Journal of Leukocyte Biology, 86: 1205-1216, 2009.

Depletion of dendritic cells enhances susceptibility to cell-free infection of HTLV-1 in CD11c-DTR transgenic mice
Rahman S, Manuel SL, Khan ZK, Wigdahl B, Acheampong E, Tangy F, Jain P
Journal of Immunology, 184(10): 5553-5561. PMCID: PMC2946091. 2010

Unique cytokine/chemokine signatures for HIV-1 and HCV mono- infection versus co-infection as determined by the Luminex® analyses
Rahman SJ, Connolly S, Manuel J, Chehimi L, Montaner, Jain P
Journal of Clinical & Cellular Immunology, 2(1): 1000104-1000108, 2011

Lack of recall response to TAX in ATL and HAM/TSP patients but not asymptomatic carriers of human T cell leukemia virus type 1
Manuel S, Sehgal M, Connolly J, Makedonas G, Gardner J, Khan ZK, Betts M, Jain P
Journal of Clinical Immunology, 33:1223-39, 2013.

An altered maturation and adhesion phenotype of dendritic cells in diseased individuals compared to asymptomatic carriers of human T-cell leukemia virus type 1
Manuel S, Sehgal M, Khan ZK, Betts M, Jain P
AIDS Research and Human Retroviruses, 29: 1273-1285, 2013.

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Breaking Down the Barrier: The effects of HIV-1 on the blood-brain barrier
Strazza M, Pirrone V, Wigdahl B, Nonnemacher N
Brain Research, 1399: 96-115. PMCID: PMC3139430. 2011

Role of Mu-opioids as cofactors in human immunodeficiency virus type 1 disease progression and neuropathogenesis
Banerjee A, Strazza M, Wigdahl B, Pirrone V, Meucci O, Nonnemacher MR
Journal of Neurovirology, 17(4): 291-302. PMCID: PMC3757547. 2011

Effect of mu-opioid agonist DAMGO on surface CXCR4 and HIV-1 replication in TF-1 human bone marrow progenitor cells
Strazza M, Banerjee A, Alexaki A, Passic SR, Meucci O, Pirrone V, Wigdahl B, Nonnemacher MR
BMC Research Notes, 7: 752, doi: 10.1186/1756-0500-7-752. PMCID: PMC4216373. 2014

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Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage
Kilareski EM, Shah S, Nonnemacher MR, Wigdahl B
Retrovirology, 6: 118. PMCID: PMC2805609. 2009

Innate and adaptive factors regulating human immunodeficiency virus type 1 genomic activation
Shah S, Nonnemacher MR, Pirrone V, Wigdahl B
Journal of Neuroimmune Pharmacology, 5(3): 278-293. PMCID: PMC3057210. 2010

Development of co-selected single nucleotide polymorphisms in the viral promoter procedes the onset of human immunodeficiency virus type 1-associated neurocognitive impairment
Li L, Aiamkitsumrit B, Pirrone V, Nonnemacher MR, Wojno A, Passic S, Flaig K, Kilareski E, Blakey B, Ku J, Parikh N, Shah S, Martin-Garcia J, Moldover B, Servance L, Downie D, Lewis S, Jacobson JM, Kolson D, Wigdahl B
Journal of NeuroVirology, 17: 92-109. PMCID: PMC3057211. 2011

Epigenetics, drugs of abuse, and the retroviral promoter
Shirazi J, Shah S, Sagar D, Nonnemacher MR, Wigdahl B, Khan ZK, Jain P
Journal of Neuroimmune Pharmacology, 8(5): 1181-1196. doi: 10.1007/s11481-013-9508-y. PMCID: PMC3878082. 2013

Functional properties of the HIV-1 long terminal repeat containing single-nucleotide polymorphisms in Sp site III and CCAAT/enhancer binding protein site I
Shah S, Alexaki A, Pirrone V, Nonnemacher MR, Wigdahl B
Virology Journal, 11: 92, doi: 10.1186/1743-422X-11-92. PMCID: PMC4047001. 2014

Defining differential genetic signatures in CXCR4- and the CCR5-utilizing HIV-1 co-linear sequences
Aiamkitsumrit B, Dampier W, Martin-Garcia J, Nonnemacher MR, Pirrone V, Ivanova T, Zhong, W, Kilareski E, Aldigun H, Frantz, B, Rimbey M, Wojno A, Passic S, William JS, Shah S, Blakey B, Parikh N, Jacobson J, Moldover B, Wigdahl B
PloS One, 9(9): e107389, doi: 10.1371/journal.pone.o107389. PMCID: PMC4180074. 2014

Modeling bone marrow progenitor cell differentiation and susceptibility to HIV-1 infection
Alexaki A, Quiterio SJ, Nonnemacher MR, Shah S, Liu Y, Banerjee A, Li L, Passic S, Kilareski E, Petrovas C, Wigdahl B
MOJ Immunology, 1(2): 0009. doi: 10.15406/moji.2014.01.00009. 2014

Impact of viral activators and epigenetic regulators on HIV-1 LTRs containing naturally occurring single nucleotide polymorphisms
Shah S, Pirrone S, Alexaki A, Nonnemacher MR, Wigdahl B
BioMed Research International, 320642. doi: 10.1155/2015/320642. PMCID: PMC4299542. 2015

HIV-1 promoter single nucleotide polymorphisms (SNPs) are associated with clinical disease severity
*Nonnemacher MR, *Pirrone V, Feng R, Moldover B, Passic S, Aiamkitsumrit B, Dampier W, Wojno A, Kilareski E, Blakey B, Ku TS, Shah S, Sullivan NT, Jacobson JM, Wigdahl B
PloSOne, 11(4): e0150835. DOI: 10.1371/journal.pone.0150835. Authors contributed equally. PMCID: PMC4839606. 2016

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Bioinformatic analysis of HIV-1 entry and pathogenesis
Aiamkitsumrit B, Dampier W, Antell G, Rivera N, Pirrone V, Nonnemacher MR, Wigdahl B
Current HIV Research, 12(2): 132-161. PMCID: PMC4382797. 2014

"Role of retrovirus-induced transactivator proteins in neuroinflammatory disease"
Antell G, Nonnemacher MR, Pirrone V, Wigdahl B
in "Neuroinflammation and Neurodegeneration." P.K. Peterson and M. Toborek (eds), Springer Science+Business Media New York, pgs. 355-385, DOI: 10.1007/978-1-4939-1071-7_17. 2014

Utilization of HIV-1 envelope V3 to identify X4- and R5-specific Tat and LTR sequence signatures
Antell GC, Dampier W, Aiamkitsumrit B, Nonnemacher MR, Jacobson JM, Pirrone V, Zhong W, Kercher K, Passic S, Williams JW, Schwartz G, Hershberg U, Krebs FC, Wigdahl B
Retrovirology, 13(1): 32. DOI: 10.1186/s12977-016-0266-9. PMCID: PMC4855882. 2016

Specific amino acids in HIV-1 Vpr are significantly associated with differences in patient neurocognitive status
Dampier W, Antell G, Aiamkitsumrit B, Nonnemacher MR, Jacobson JM, Pirrone V, Zhong W, Kercher K, Passic S, Williams JW, James A, Devlin KN, Giovannetti T, Libon DJ, Szep Z, Ehrlich G, Wigdahl B, Krebs FC
Journal of NeuroVirology, July 11. DOI: 10.1007/s13365-016-0462-3. PMCID: PMC5226925. 2016

Evidence of divergent amino acid usage in comparative analyses of R5- and X4-associated HIV-1 Vpr sequences
Antell GC, Dampier W, Aiamkitsumrit B, Nonnemacher MR, Pirrone V, Zhong W, Kercher K, Passic S, Williams J, Liu Y, James T, Jacobson JM, Szep Z, Wigdahl B, Krebs FC
International Journal of Genomics, 4081585. DOI: 10.1155/2017/4081585. PMCID: PMC5460428. 2017