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Ogechukwu Menkiti

Ogechukwu Menkiti, MD

Professor


Department: Pediatrics

Specialties: Neonatal-Perinatal Medicine, Pediatrics

Education

  • Higher Diploma in Childhood Medicine (DCh) - University College Dublin, Dublin, Republic of Ireland (2001)
  • MBBS - School of Medicine, University of Nigeria, Enugu (1998)

Awards & Honors

  • Collaborating Physician Award Presented by Tower Health Advanced Practice Provider Week Planning Committee (2022)
  • Oksana Korzeniowski Patient Care Award, Drexel University College of Medicine, Philadelphia, Pa. (2020)
  • Seeds Award, St Christopher’s Hospital for Children, for exemplary communication with referring physicians (2017)
  • Eastern Society for Pediatric Research Travel Award (2010)
  • PAS Young Investigator’s Travel Award (2009)
  • Resident of the Year Award for Best Bedside Manner, Bronx Lebanon Hospital Center (2007)
  • Resident of the Year Award for Best Nurse/MD Collaboration, Bronx Lebanon Hospital Center (2007)
  • Residents Teaching Award, Bronx Lebanon Hospital Center, for medical student education (2004)

Memberships / Professional Affiliations

  • Fellow, American Academy of Pediatrics
  • Philadelphia Perinatal Society
       President, 2014-2016

Ogechukwu Menkiti, MD, is an attending neonatologist and perinatologist at St. Christopher's Hospital for Children. His clinical interests include the treatment of pediatric patients with cardiopulmonary failure, disorders of the newborn, respiratory failure and persistent pulmonary hypertension of the newborn. Dr Menkiti has won several awards including Oksana Korzeniowski Patient Care Award for his outstanding skills and commitment in the clinical care of patients and teaching which substantially improved the skills and knowledge of residents, students and faculty.

Clinical Services

Neonatal-perinatal medicine

Internships

  • Rotating Housemanship in Medicine and Surgery - University of Nigeria Teaching Hospital, Enugu (1999)
  • Pediatrics - Bronx Lebanon Hospital Center/Albert Einstein College of Medicine of Yeshiva University (2005)

Residencies

  • Pediatrics - Bronx Lebanon Hospital Center/Albert Einstein College of Medicine of Yeshiva University (2007)

Fellowships

  • Neonatal-Perinatal Medicine - University of Pennsylvania School of Medicine (2010)

Affiliated Hospitals

St. Christopher's Hospital for Children

Ogechukwu Menkiti, MD, is a professor in the Department of Pediatrics at Drexel University College of Medicine. He is the vice chair for outreach, community partnerships, and innovation/integration at St Christopher’s Hospital for Children. He is the medical director of the Extracorporeal Membrane Oxygenation Program and the Regional Fetal Evaluation Program at St Christopher’s Hospital for Children.

Research

Dr. Menkiti’s research interests include defining the inflammatory response to extracorporeal membrane oxygenation in the pediatric population following initiation of ECMO. Dr Menkiti designed an ex vivo ECMO model that allows the study of blood- circuit interactions and its contribution to the resultant inflammatory milieu created in pediatric ECMO patients.

In the Media

"Vasopressin Found to Ease PH Symptoms in Newborns: Case Series"
Pulmonary Hypertension News (July 11, 2022)

Publications

Publications in Peer-Reviewed Journals

“Extracorporeal Membrane Oxygenation (ECMO) for Suspected Neonatal Genetic Diagnoses with Cardiorespiratory Failure”
*Ikeri K, Quinones Cardona V, Joshi S, Menkiti OR
Journal of Extracorporeal Technology. Accepted 24 April 2023

“Characteristics and outcomes of an international cohort of 600, 000 hospitalized patients with COVID-19”
* ISARIC Clinical characterization Group
Int J Epidemiol. 2023 Apr 19;52(2):355-376. doi: 10.1093/ije/dyad012. PMID: 36850054; PMCID: PMC10114094

“Neurological manifestations of COVID-19 in adults and children”
* ISARIC Clinical Characterization Group
Brain. 2023 Apr 19;146(4):1648-1661. doi: 10.1093/brain/awac332. PMID: 36087305; PMCID: PMC9494397

“Pediatric COVID-19 mortality: a database analysis of the impact of health resource disparity”
* International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) Clinical Characterization Group Investigators
BMJ Pediatr Open. 2022 Oct;6(1): e001657. doi: 10.1136/bmjpo-2022-001657. PMID: 36645791; PMCID: PMC9621167

“Respiratory Support in Patients with Severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 Study: A Prospective, Multinational, Observational Study”
* ISARIC Characterization Group
Crit Care. 2022 Sep 13;26(1):276. doi: 10.1186/s13054-022-04155-1. PMID: 36100904; PMCID: PMC9469080

“ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19”
* ISARIC Clinical Characterization Group
Sci Data. 2022 Jul 30;9(1):454. doi: 10.1038/s41597-022-01534-9. PMID: 35908040; PMCID: PMC9339000

“Use of vasopressin in persistent pulmonary hypertension of the newborn: A case series”
*Joshi S, Quinones Cardona V, Menkiti OR
SAGE Open Med Case Rep. 2022 Jun 7;10:2050313X221102289. doi: 10.1177/2050313X221102289. PMID: 35693924; PMCID: PMC9178974 (2022)

“Bleeding complications in Neonates receiving Extracorporeal Membrane Oxygenation and Controlled Hypothermia”
*Joshi S, Quinones Cardona V, Poletto E, Menkiti OR
Am J Perinatol. 2022 Mar 3. doi: 10.1055/a-1786-8688. PMID: 35240700 (2022)

“The Value of Open-Source Clinical Science in Pandemic Response: Lessons from ISARIC”
*ISARIC Clinical Characterization Group
Lancet Infect Dis. 2021 Dec;21(12):1623-1624. doi: 10.1016/S1473-3099(21)00565-X. Epub 2021 Oct 4. Erratum in: Lancet Infect Dis. 2021 Dec;21(12):e363. PMID: 34619109. PMCID: PMC8489876 (2021)

“Ten Months of Temporal Variation in the Clinical Journey of Hospitalized Patients with COVID-19: An Observational Cohort”
*ISARIC Clinical Characterization Group, Hall MD, Baruch J, Carson G, Citarella BW, Dagens A, Dankwa EA, Donnelly CA, Dunning J, Escher M, Kartsonaki C, Merson L, Pritchard M, Wei J, Horby PW, Rojek A, Olliaro PL
Elife. 2021 Nov 23;10:e70970. doi: 10.7554/eLife.70970. PMID: 34812731. PMCID: PMC8791638 (2021)

“Severe Pulmonary Hemorrhage in a Neonate with Hypoxic Ischemic Encephalopathy and Sepsis Managed on Extracorporeal Membrane Oxygenation”
*Quinones Cardona V, Joshi S, Conway D, Menkiti OR
ASAIO J. 2021 Jul 15. doi: 10.1097/MAT.0000000000001520. Epub ahead of print. PMID: 34264871 (2021)

“Improving Timeliness of Newborn Screens in the Neonatal Intensive Care Unit: A Quality Improvement Initiative”
*Ikeri K, Quinones Cardona V, Menkiti OR
J Perinatol. 2021 May;41(5):1166-1173. doi: 10.1038/s41372-021-00985-z. Epub 2021 Mar 23. PMID: 33758386. PMCID: PMC7985587 (2021)

“Case of Lactic Acidosis in a Term Neonate” Index of Suspicion in the Nursery
*Ugwu N, Ikeri K, Goenka S, Menkiti O
Neoreviews. 2021 Jan;22(1):e52-e54. doi: 10.1542/neo.22-1-e52. PMID: 33386314 (2021)

“ECMO as a Platform for Ammonia Removal in a Neonate with Multi-Enzyme Urea Cycle Disorder”
*Ikeri K, Quinones Cardona V, Hagan-Brown A, Young M, Schneider M, Menkiti OR
Journal of Extracorporeal Technology. Feb 29, 2020. PMID: 32280145 (2020)

“Streptococcus Pyogenes Purpura Fulminans and Septic Shock: A Case Highlighting the Ethical Considerations of High-Risk Extracorporeal Membrane Oxygenation”
*Wheaton T, Menkiti O, Misra A
The International Journal of Artificial Organs. 2020 Jul;43(7):500-502. doi: 10.1177/0391398820901832. Epub 2020 Jan 25. PMID: 31984828 (2020)

“Management Strategies during a VA ECMO Run in a Neonate with E. Coli Septic Shock Masquerading as Hypoxic Ischemic Encephalopathy”
*Quinones Cardona V & Menkiti OR
Journal of Extracorporeal Technology. 2019 Jun;51(2):88-93. PMID: 31239582. PMCID: PMC6586266 (2019)

“Newborn Infant with Mothball Toxicity due to Maternal Ingestion”
*Sahni M, Vibert Y, Bhandari V, Menkiti O
Pediatrics. 2019 Jun;143(6):e20183619. doi: 10.1542/peds.2018-3619. Epub 2019 May 7 PMID: 31064798 (2019)

“Population Pharmacokinetics of Gentamicin in Neonates with Hypoxemic-Ischemic Encephalopathy Receiving Controlled Hypothermia”
*Cies JJ, Habib T, Bains V, Young M, Menkiti OR
Pharmacotherapy. 2018 Nov;38(11):1120-1129. doi: 10.1002/phar.2186. Epub 2018 Oct 24. PMID: 30300445 (2018)

“Transition to Routine Premedication for Nonemergent Intubations in a Level IV Neonatal Intensive Care Unit”
*Fleishman R, Mossabeb R, Menkiti O, Young M, Bains V, Cooperberg D
Amer J Perinatol. 2018 Mar; 35(4):336-344. doi: 10.1055/s-0037-1607282. Epub 2017 Oct 11. PMID: 29020695 (2018)

“Diagnostic Potential of Neural Exosome Cargo as Biomarkers for Acute Brain Injury”
*Goetzl L, Merabova N, Darbinian N, Martirosyan D, Poletto E, Fugarolas K, Menkiti O
Annals of Clinical and Translational Neurology. 2017 Nov 24;5(1):4-10. doi: 10.1002/acn3.499. eCollection 2018 Jan. PMID: 29376087. PMCID: PMC5771318 (2017)

“Population Pharmacokinetics and Pharmacodynamic Target Attainment of Ampicillin in Neonates with Hypoxemic-Ischemic Encephalopathy in the Setting of Controlled Hypothermia”
*Cies J, Fugarolas KN, Moore WS II, Mason RW, Menkiti OR
Pharmacotherapy. April 2017, 37(4):456-463. doi: 10.1002/phar.1916. Epub 2017 Mar 30. PMID: 28226400 (2017)

“The Microbiota Regulates Neutrophil Homeostasis and Host Resistance to Escherichia Coli K1 Sepsis in Neonatal Mice”
*Deshmukh HS, Liu Y, Menkiti O, Mei J, Dai N, O'Leary CE, Oliver PM, Kolls JK, Weiser JN, Worthen GS
Nature Med. 2014 May;20(5):524-30. doi: 10.1038/nm.3542. Epub 2014 Apr 20. PMID: 24747744. PMCID: PMC4016187 (2014)

“Multiple Epuli in a Newborn: A Case Report”
*Ahmad M, Chennupati SK, Menkiti OR, Terk A
International Journal of Pediatric Otorhinolaryngology Extra. Volume 9, Issue 3, September 2014, Pages 75-78. February 2014. doi:10.1016/j.pedex.2014.02.002 (2014)

Presentations

Recent Peer-Reviewed Abstracts: Platform and Poster Presentations

“Characterization of Neurodevelopmental Follow-up Programs within the Children’s Hospital’s Neonatal Consortium”
Quinones Cardona V, Cohen S, Sewell E, Kojima K, Chandel A, Jano E, Peeples E, Lee KS, Ogechukwu Menkiti, DiGeronimo R, Mietzu U, Rao R, Dizon M
Presented at CHNC Annual Symposium, Denver Colo., October 2023

Presented at The Extracorporeal Life Support Organization, 34th Annual ELSO Conference, Seattle, Wash., September 2023

  • “Blood prime and circuit interplay does not potentiate inflammation in Extracorporeal Membrane Oxygenation”
    Swosti Joshi, Htay Aung, Ta’Teanna Revels, Vilmaris Quinones-Cardona, Ogechukwu Menkiti
  • “Single Center Experience with Percutaneous Cannulation in Neonatal Veno-Venous ECMO”
    Vilmaris Quinones-Cardona, Ashitha Rajeurs, Jillian Deacon, Swosti Joshi, Ogechukwu Menkiti

Presented at the Pediatric Academic Societies (PAS) 2023 Meeting, Washington, DC, April 27-May 1, 2023

  • “Moderate sedation strategy during laser surgery can reduce intubations and related risks in neonates with retinopathy of prematurity in a level IV NICU”
    Quinones-Cardona V, Byrne E, Arthur A, Young M, Lavery D, Carroll A, Joshi S, Kehinde F, Menkiti O
  • “Blood Prime-Circuit Interplay Does Not Explain the Inflammogenic Effect of Extracorporeal Membrane Oxygenation in Pediatric Patients”
    Michelle Mejia, Swosti Joshi, Vilmaris Quinones Cardona, Alison J Carey, Ogechukwu Menkiti

Presented at the 39th Annual Children's National Symposium ECMO and the Advanced Therapies for Cardiovascular and Respiratory Failure, Keystone, Colo., February 26 - March 1, 2023

  • “Pro-inflammatory Cytokines are not responsible for systemic inflammatory response syndrome in pediatric Extracorporeal membrane oxygenation patients”
    Swosti Joshi, Jimmikumar Patel, Vilmaris Quinones-Cardona, Jillian Deacon, Alison J. Carey, Ogechukwu Menkiti
  • “Blood prime-circuit interactions do not induce inflammatory cytokine response in an ex-vivo ECMO circuit model”
    Michelle Mejia, Swosti Joshi, Vilmaris Quinones Cardona, William Bain, Laura Cort, Ogechukwu Menkiti

Presented at The Extracorporeal Life Support Organization, 33rd Annual ELSO Conference, Boston, Mass., September 2022

  • “Use of phenobarbital as a strategy to reduce opioid and benzodiazepine use in neonatal extracorporeal membrane oxygenation”
    Quinones-Cardona V, Byrne E, Mejia M, Joshi S, Menkiti OR
  • “The role of the Extracorporeal Membrane Oxygenation circuit in inducing inflammation Ex vivo
    Joshi S, Quinones-Cardona V, Deacon J, Mejia M, Carey A, Menkiti OR
    Robert H Bartlett (RHB) Award, ASAIO Journal. 68(S3):1-76, September 2022

“A Pilot Multimodal Structured Communication Curriculum for Neonatology Fellows Utilizing Simulation in the Delivery of Difficult News”
Erickson J, Quinones-Cardona, V, Joshi S, Lewis K, Menkiti OR
Presented at the annual meeting of the Pediatric Academic Society, Board #1176805, Denver, Colo., April 22, 2022

“Early Use Experience of the Novel Crescent RA Neonatal VV-ECMO Cannula Among CHNC ECMO Focus Group Members”
Gray B, Carr N, Chapman R, Chi A, Dariva V, Dirnberger D, Fernandes C Hamrick S, Keene S, Linden A, Makkar A, Menkiti OR, Miquel-Verges F, Quinones-Cardona V, Rao R, Rodriguez R, Seabrook R, Suttner D, Weems M, Rintoul N, DiGeronimo R, CHNC ECMO Focus Group
Presented at the 38th Annual Children’s National Symposium: ECMO and the Advanced Therapies for Respiratory Failure Symposium, Keystone, Colo., February 2022

“Reducing Turnaround Time (TAT) of Newborn Screens in a Level IV NICU: A Quality Improvement Initiative”
Ikeri K, Quinones-Cardona V, Menkiti OR
Presented at the annual meeting of the Pediatric Academic Societies, Board #583, Philadelphia, Pa., May 2, 2020

“Utility of Vasopressin Rescue Therapy in Neonates with Persistent Pulmonary Hypertension of the Newborn”
Joshi S, Quinones-Cardona V, Menkiti OR
Presented at the annual meeting of the Pediatric Academic Society, Board #534, Philadelphia, Pa., May 5, 2020

Presented at the annual meeting of the Extracorporeal Life Support Organization, 30th Annual ELSO Conference, Austin, Texas, September 12-15, 2019

  • “Successful use of VA-ECMO in a Neonate with Multi-Enzyme Urea Cycle Defect”
    Ikeri K, Quinones-Cardona V, Menkiti OR
  • “Bleeding complications and MRI findings among neonates receiving Controlled Hypothermia and Extracorporeal Membrane Oxygenation”
    Joshi S, Quinones-Cardona V, Abdallah B, Poletto E, Menkiti OR
  • “Neuro-imaging and Neurodevelopmental Outcomes in Neonates with Hypoxic Ischemic Encephalopathy Who Received Extracorporeal Membrane Oxygenation and Controlled Hypothermia”
    Joshi S, Quinones-Cardona V, Taylor J, Poletto E, Menkiti OR

“Outcomes of Controlled Hypothermia versus Combined Controlled Hypothermia with Extracorporeal Membrane Oxygenation in Neonates: A Tertiary Center`s Experience”
Joshi S, Quinones-Cardona V, Abdallah B, Menkiti OR
Presented at the Pediatric Academic Society, Board #595, Baltimore, Md., April 30, 2019

“Safety of Therapeutic Hypothermia in Combination with Extracorporeal Membrane Oxygenation in Neonates with Moderate to Severe Hypoxic-Ischemic Encephalopathy with Cardiac or Respiratory Failure”
Joshi S, Quinones-Cardona V, Blutstein R, Gilliam N, Low T, Menkiti OR
Presented at the Extracorporeal Life Support Organization ELSO, 29th Annual Conference, Scottsdale, Ariz., September 13-16, 2018

Presented at the annual meeting of the Extracorporeal Life Support Organization, 29th Annual ELSO Conference, Scottsdale, Ariz., September 13-16, 2018

  • "Safety of therapeutic hypothermia in combination with extracorporeal membrane oxygenation in neonates with moderate to severe hypoxic-ischemic encephalopathy with cardiac or respiratory failure"
    Joshi S, Quinones-Cardona V, Blutstein R, Gilliam N, Low T, Menkiti O
  • "Management Strategies during a Challenging VA ECMO Run in a Neonate with Septic Shock and Hypoxic Ischemic Encephalopathy: A Case Report"
    Quinones-Cardona V, Conway D, Gilliam N, Low Tm Menkiti O

"Neuronal Exosome Synaptopodin: An Early Predictor of Therapeutic Response to Controlled Hypothermia"
Goetzl L, Martirosyan D, Darbinian N, Merabova N, Fugarolas K and Menkiti O
Present at annual meeting of the Society for Reproductive Investigation 64thAnnual Scientific Meeting “D2D: Data to Discovery," Orlando, Florida, March 15-18, 2017

"Evaluating the Effectiveness of a Novel Neonatal Virtual Simulation Model in Training on Management of Neonatal Emergencies"
Kolb, K, Calaman, S, Menkiti O,McGowan, J; Deifenbach P, Bernstein B, Wells, Shannon
Presented at:
   -Annual meeting, Pediatric Academic Societies, Baltimore, Maryland, April 30-May 3, 2016
   -Annual meeting, Eastern Society for Pediatric Research, Philadelphia, Pennsylvania, March 11-13, 2016
   -International Meeting on Simulation in Healthcare, San Diego, California, January 16-20, 2016
   (Awarded 3rd Best Pediatric Poster at the Pediatric Section Meeting)

Ampicillin Pharmacokinetics in Neonates with Hypoxic Ischemic Encephalopathy in the Setting of Controlled Hypothermia
Fugarolas K, Menkiti O, Moore WA, II, Chopra A, Mason RW, Cies JJ
Presented at the annual meeting of the American Society for Microbiology 54th ICAAC, Washington D.C., September 5-7 2014

Presented at the annual meeting of the Pediatric Academic Societies, Washington DC, May 4-7, 2013

  • "From Residency to First Night On-call as a Fellow: Simulation is a Potent Tool to Smooth Transition and Reduce Anxiety"
    Menkiti O, Halligan MJ, Zubrow AB, Calaman S
  • "Assessing the Cardioprotective Properties of Controlled Hypothermia in Neonates with Moderate to Severe Hypoxic Ischemic Encephalopathy Utilizing Cardiac Troponin I"
    Menkiti O, Alexander J.P, Wallace J, Obiri N

Presented at the annual meeting of the Eastern Society for Pediatric Research, Philadelphia, Pa., March 22-24, 2013

National Workshop

"Beyond The Mega Code: How To Adapt Teaching Strategies When Designing Simulation Exercises Across The Continuum Of Learners"
Presented at annual meeting of the Pediatric Academic Societies, Washington DC, May 4-7, 2013
Facilitators: Menkiti OR, Dickermann M, Calaman S.

Other Abstracts

Utility of Cardiac Troponin as a marker for cardiac injury in Neonates with Hypoxic Ischemic Encephalopathy undergoing Controlled Hypothermia.
Dick DA, Menkiti O, Cartagena M, Kehinde F, Vineet Bhandari
Presented at Drexel University College of Medicine Discovery Day 2017

St. Christopher's Hospital for Children is a primary academic campus of Drexel University College of Medicine. Its physicians are non-compensated members of the teaching faculty of Drexel University College of Medicine and its clinical practices are independent of Drexel University.


Contact Information


St. Christopher's Hospital for Children
160 East Erie Avenue
Philadelphia, PA 19134
Phone: 215.427.5202
Fax: 215.427.8192