Selected Research Publications
See full publication list.
“IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition”
Haslund-Gourley, B.S., Woloszczuk, K., Hou, J.,... Comunale M.A.
Nat Commun 15, 404 (2024). https://doi.org/10.1038/s41467-023-44211-0
“IgG N-glycan signatures as potential diagnostic and prognostic biomarkers”
Haslund-Gourley, B., Wigdahl, B., and Comunale, M.A.
Diagnostics, 13(6), 1016. doi:https://doi.org/10.3390/diagnostics13061016 (2023)
“Acute Lyme disease IgG N-linked glycans contrast the canonical inflammatory signature”
Haslund-Gourley, Grauzam, S., Mehta, A.S., Wigdahl, B., and Comunale, M.A.
Frontiers in Immunology, 13, 949118–949118. https://doi.org/10.3389/fimmu.2022.949118 (2022)
ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses
Ma J., Zhang X, Soloveve V, Warren T, Guo F, Wu S, Su Q, Shen H, Solon E, Comunale MA, Mehta A, Guo J, Savari S, Du Y, Block T and Chang J
Antiviral Research, 150, 112-122. doi:10.1016/j.antiviral.2017.12.008, 2018
Inside front cover: Development and application of a novel recombinant aleuria aurantia lectin with enhanced core fucose binding for identification of glycoprotein biomarkers of hepatocellular carcinoma
Norton P, Comunale MA, Herrera H, Wang M, Houser J, Wimmerova M, Romano P and Mehta A
Proteomics, 16(24), 3126-3136. doi:10.1002/pmic.201600064, 2016
Host erythrocyte environment influences the localization of exported protein 2, an essential component of the Plasmodium translocon
Meibalan E, Comunale MA, Lopez AM, Bergman LW, Mehta A, Vaidya AB and Burns JM Jr.
Eukaryot Cell, 14(4), 371-384. doi:10.1128/EC.00228-14, 2015
Total serum glycan analysis is superior to lectin-FLISA for the early detection of hepatocellular carcinoma
Comunale MA, Wang M, Anbarasan N, Betesh L, Karabudak A, Moritz E, Devarajan K, Marrero J, Block T, Mehta A
Proteomics Clin Appl, 7(9-10), 690-700. doi:10.1002/prca.201200125, 2013
"Linkage Specific Fucosylation of Alpha-1-Antitrypsin in Liver Cirrhosis and Cancer Patients: Implications for a Biomarker of Hepatocellular Carcinoma"
Comunale MA, Rodemich-Betesh L, Hafner J, Wang M, Norton P, et al.
PLoS ONE, 5(8): e12419, 2010
"Identification and development of fucosylated glycoproteins as biomarkers of primary hepatocellular carcinoma"
Comunale MA, Wang M, Hafner J, Krakover J, Rodemich L, Kopenhaver B, Long RE, Junaidi O, Bisceglie AM, Block TM, and AS Mehta
Journal of Proteome Research, 8(2): 595-602, 2009.
"Novel fucosylated biomarkers for the early detection of hepatocellular carcinoma"
Wang M, Long RE, Comunale MA, Junaidi O, Marrero J, Di Bisceglie, AM, Block, TM, and AS Mehta
Cancer Epidemiology, Biomarkers & Prevention, 18(6): 1914-1921, 2009.
"Glycomic characterization of prostate-specific antigen and prostatic acid phosphatase in prostate cancer and benign disease seminal plasma fluids"
White KY, Rodemich L, Nyalwidhe JO, Comunale MA, Clements MA, Lance RS, Schellhammer PF, Mehta AS, Semmes OJ, and RR Drake
Journal of Proteome Research, 8(2): 620-630, 2009.
"N-linked glycosylation of the liver cancer biomarker GP73"
Norton PA, Comunale MA, Krakover J, Rodemich L, Pirog N, D'Amelio A, Philip R, Mehta AS, and TM Block
Journal of Cell Biochemistry, 104(1): 136-149, 2008.
"Increased levels of galactose-deficient anti-Gal immunoglobulin G in the sera of hepatitis C virus-infected individuals with fibrosis and cirrhosis"
Mehta AS, Long RE, Comunale MA, Wang M, Rodemich L, Krakover J, Philip R, Marrero JA, Dwek RA, and TM Block
Journal of Virology, 82(3): 1259-1270, 2008.
"Proteomic analysis of serum associated fucosylated glycoproteins in the development of primary hepatocellular carcinoma"
Comunale MA, Krakover J, Lowman M, Long RE, Philip R, Seeholzer S, Evans AA, Hann HWL, Block TM, and AS Mehta
Journal of Proteome Research, 6(5): 308-315, 2006.
"Use of targeted glycoproteomics to identify serum glycoproteins that correlate with liver cancer in woodchucks and humans"
Block TM, Comunale MA, Romano PM, Lowman M, Fimmel C, Tennant BT, Evans A, London WT, Blumberg B, Dwek RA, Mattu TS, and A Mehta
Proceedings of the National Academy of Sciences USA, 102 (3): 779--84, 2005.
"GP73, a resident Golgi glycoprotein, is a novel serum marker for hepatocellular carcinoma"
Marrero JA, Romano PR, Nikolaeva O, Steel L, Mehta A, Fimmel CJ, Comunale MA, D'Amelio A, Lok AS, and TM Block.
Journal of Hepatology, 43(6): 1007-1012, 2005.
"Comparative proteomic analysis of de-N-glycosylated serum from hepatitis B carriers reveals polypeptides that correlate with disease status"
Comunale MA, Mattu TS, Lowman M, Evans A, London WT, Dwek RA, Block TM, and A Mehta
Proteomics: 4(3): 826-838, 2004.
Book Chapters
Glycosylation and Hepatocellular Carcinoma.
Comunale MA and Mehta A
In M. Dunn, L. Jorde, P. Little and S. Subramaniam (Eds.), Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics (Vol. 3): Wiley, 2006
Glycoproteomic Analysis by Two Dimensional Electrophoresis
Comunale MA and Mehta A
In M.A. Tainsky (Ed.), Tumor Marker Discovery (Vol. 520, pp. 59-74): Humana Press, 2009