• Post-doctoral research, University of Virginia, Department of Internal Medicine (2009-2011)

Dr. Sen is the lab manager of the Genomics Core Facility of Drexel University College of Medicine and a member of the Center for Advance Microbial Processing.

Area of Research

Dr. Sen’s research interest is on the molecular microbiology of bacterial pathogenesis and the next generation sequencing particularly regarding species-specific microbiome studies and comparative bacterial genomics. Her research addresses some of the most pressing issues in understanding how to treat bacterial infections using knowledge of bacterial processes and metabolism; a pursuit that encompassed treatment of tularemia, hospital-borne infections, middle-ear infections and chronic obstructive pulmonary disease in adults, among other ailments. Her graduate study included the evaluation of new-generation serologic tests for the diagnosis of typhoid fever, using data from a community-based surveillance study in Calcutta, India. She utilizes the Next Generation Sequencing for understanding bacterial pathogenesis and virulence with a focus on microbiome and bacterial genomics.

Could a Breakdown in the Brain’s Networks Allow Infections to Contribute to Alzheimer’s Disease?
Drexel News (September 13, 2023)

View a complete list of Dr. Sen's publications on Google Scholar.

Selected Publications

“Species-level profiling of Ixodes pacificus bacterial microbiome reveals high variability across short spatial scales at different taxonomic resolutions”
Socarras KM, Earl JP, Krol JE, Bhat, Pabilonia M, Harrison MH, Lang SP, Sen B, Ahmed A, Hester M, Mell JC, Vandergrift K, Ehrlich GD
Genet Test Mol Biomarkers. 2021 Aug;25(8):551-562

“The bacterial microbiota of Hunner lesion interstitial cystitis/bladder pain syndrome”
Nickel JC, Ehrlich GD, Krol JE, Ahmed A, Sen B, Bhat A, Mell JC, Doiron RC, Kelly KL, Earl JP
BJU Int. 2022 Jan;129(1):104-112

“MAPP Research Network. A Culture-Independent Analysis of the Microbiota of Female Interstitial Cystitis/Bladder Pain Syndrome Participants in the MAPP Research Network”
Nickel JC, Stephens-Shields AJ, Landis JR, Mullins C, van Bokhoven A, Lucia MS, Henderson JP, Sen B, Krol JE, Ehrlich GD
J Clin Med. 2019;8(3)

“Species-level bacterial community profiling of the healthy sinonasal microbiome using Pacific Biosciences sequencing of full-length 16S rRNA genes”
Earl JP, Adappa ND, Krol J, Bhat AS, Balashov S, Ehrlich RL, Palmer JN, Workman AD, Blasetti M, Sen B, Hammond J, Cohen NA, Ehrlich GD, Mell JC
Microbiome. 2018 Oct 23;6(1):190. doi: 10.1186/s40168-018-0569-2. PMID: 30352611; PMCID: PMC6199724

“Studies on Acinetobacter baumannii involving multiple mechanisms of carbapenem resistance”
Sen B, Joshi SG
J Appl Microbiol. 2016 Mar;120(3):619-29

“The fslE homolog, FTL_0439 (fupA/B), mediates siderophore-dependent iron uptake in Francisella tularensis LVS”
Sen B, Meeker A, Ramakrishnan G
Infect Immun. 2010 Oct;78(10):4276-85. doi: 10.1128/IAI.00503

“In vitro activity of cefpodoxime, an expanded-spectrum cephalosporin, against Salmonella enterica serotype typhi”
Sen B, Bhattacharya M, Niyogi SK
Antimicrob Agents Chemother. 2008 Feb;52(2):802-3. doi: 10.1128/AAC.00867-07. Epub 2007 Nov 26. PMID: 18039924; PMCID: PMC2224739

“Phage typing, biotyping & antimicrobial resistance profile of Salmonella enterica serotype Typhi from Kolkata”
Sen B, Dutta S, Sur D, Manna B, Deb AK, Bhattacharya SK, Niyogi SK
Indian J Med Res. 2007 May;125(5):685-8. PMID: 17642505

“The first outbreak of acute diarrhea due to a pandemic strain of Vibrio parahaemolyticus O3:K6 in Kolkata, India”
Sen B, Dutta B, Chatterjee S, Bhattacharya MK, Nandy RK, et al.
Int J Infect Dis. 2007 Mar;11(2):185-7