Biophysics Research Group

Department of Physics

Drexel Physics Department – Biophysics Research Group

What is biophysics research?

Faculty in Drexel’s Department of Physics are conducting biophysics research in a number of exciting areas. Learn more about current biophysics research areas below.

Let's build a new introduction.

  • Begin with a brief, inspiring definition of the research area. For example: What is biophysics research?
  • Consider that our reader may be 16 years old.
  • Broadly, what does this research group explore?
  • Why? What is the group motivated by?
  • What are the goals of the group?
  • What do you hope to advance, promote, understand?
  • How does it make an impact?
  • Why does it matter?
  • Does research promote health equity for disadvantaged populations?

Some phrasing to consider:
Our research covers wide areas of . . . Our group emphasizes . . . Our primary research investigates, explores, examines . . . Our long-term goals are . . . The discoveries we make contribute to . . . Our discoveries inspire the next generation of students. . .

Research Topics

  • Dynamics of Biomolecules
  • Force Transduction in Muscle
  • Neurodegenerative Diseases
  • Phase Transitions in Biology
  • Protein Folding and Self-Assembly
  • Systems biology and bio-networks
  • Ultrafast Laser Spectroscopy

Projects


Facilities

  • Biomanipulation and Microscopy Laboratories: Four optical tables and six research grade microscopes are configured to perform microscopic spectroscopy and manipulation on solutions and individual cells. A spatial light modulator allows spatial patterns to be encoded on samples and explored; all microscopes are temperature-controlled with state-of-the-art cameras, including a 2,000 frame-per-second high-speed system. Each optical table is also equipped with high power lasers for photolysis or fluorescence spectroscopy.
  • Microfluidic attachments are available for use, and a small microfluidic fabrication facility has also been established.
  • The fluorescence microscope resolves fast biomolecular dynamics in living cells.
  • The Computational Biophysics Facility also includes two Beowulf clusters (44-node dual-core Xeon, 43-node dual quad-core Xeon [344 cores]), 24 TB RAID disk server, and 10 Linux workstations connected through a gigabit network.

Faculty

Faculty member Contact Research Interests Research Discovery
Luis Cruz Cruz, PhD, associate professor of Physics, Drexel University
Associate Professor; Associate Head for Undergraduate Studies
Disque Hall 912
ccruz@drexel.edu
  • Spiking Neural Networks
  • Synchronization in the firings of Neuronal Networks
  • Micro/Minicolumns in the brain
  • Brain Plasticity
  • Traveling Waves in Low Dimensional Neuronal Networks
  • Spatial correlations of neurons in the brain
  • Confinement effects on the folding of amyloidogenic proteins

Publications



Dr. Frank Ferrone
Professor
Disque Hall, room 922
fferrone@drexel.edu
  • Sickle cell
  • Protein self-assembly theory
  • Molecular crowding
  • Novel optical methods
  • Microscopy
  • Kinetics

Publications

Brigita Urbanc, PhD, professor of Physics at Drexel University
Professor; Associate Department Head for Graduate Studies
3141 Chestnut Street, 12-909,
Philadelphia, PA 19104
bu25@drexel.edu
  • Intrinsically disordered proteins
  • Biophysics of protein folding and self-assembly relevant to Alzheimer's and Parkinson's disease
  • Protein-protein and protein-lipid interactions
  • Discrete and all-atom molecular dynamics
  • Molecular dynamics force field development

Publications