The American Civil War began in 1861 and was fought between the rebel secessionist Confederate States of America in the American South, and the rest of the United States of America, calling themselves the Union. The war ended in 1865 and resulted in over an estimated 850,000 deaths. The carnage of war was a clear cause for doctors and nurses to be utilized on and off the battlefield, and the American Civil War saw many women doctors and nurses take part in this medical effort. This blog post summarizes the story of several woman doctors and graduates of Woman’s Medical College of Pennsylvania who served in the civil war. These women, Dr. Orianna Moon-Andrews, Dr. Chloe Buckle, Anne Smith, and Dr. Mary Edwards Walker, all have material stored in the Legacy Center Archives, and contributed their medical knowledge as nurses and physicians in the American Civil War.