Imaging Glaucoma: Unraveling the Pathophysiology of a Leading Cause of Irreversible Blindness

Wednesday, March 4, 2026

2:30 PM-4:00 PM

BIOMED Seminar

Title:
Imaging Glaucoma: Unraveling the Pathophysiology of a Leading Cause of Irreversible Blindness

Speaker:
Gadi Wollstein, MD
Co-Director Advanced Center of Ophthalmic Research in Neuroimaging (ACORN)
Director of Research Training and Education
Vickie and Jack Farber Vision Research Center
Wills Eye Hospital

Details:
Glaucoma is a leading cause of irreversible blindness worldwide, yet the underlying mechanisms driving the disease remain incompletely understood. Advances in ocular imaging have transformed both clinical care and glaucoma research by enabling noninvasive, high-resolution, longitudinal quantitative assessment of ocular structures affected by the disease. In this presentation, we highlight key ocular imaging technologies and challenges in image processing, data integration, algorithm development, and longitudinal analysis. We demonstrate how data generated by these devices have provided new insights into glaucoma pathophysiology, deepening our understanding of disease initiation and progression and informing future diagnostic and therapeutic strategies.

Biosketch:
Gadi Wollstein, MD, is a Professor of Ophthalmology, Co-Director of the Advanced Center of Ophthalmic Research in Neuroimaging (ACORN), and the Director of Research Training and Education, Vickie and Jack Farber Vision Research Center at Wills Eye Hospital. He is a Professor of Ophthalmology at the Sidney Kimmel Medical College at Thomas Jefferson University. After completing his clinical training in Israel, Dr. Wollstein has been a research fellow in Moorfields Eye Hospital in London, UK, followed by a second fellowship in Tufts-New England Medical Center, Boston, MA, where he investigated the use of imaging devices to detect and longitudinally monitor subjects with glaucoma. Before joining Wills Eye Hospital, Dr. Wollstein directed his laboratory in NYU School of Medicine and University of Pittsburgh, for more than two decades. 

Dr. Wollstein’s research is primarily funded by the National Institute of Health (NIH), and Robert M. Sienskey Foundation, and focuses on the use of ocular imaging technologies to detect, monitor and investigate the pathophysiology of glaucoma. His studies were summarized in more than 260 peer review manuscripts, and more than 75 reviews and book chapters. He is an active and former reviewer for the NIH, Veteran Administration (VA), Fight for Sight, and Research to Prevent Blindness foundations, several international funding agencies and numerous ophthalmic journals.

Contact Information

Carolyn Riley
cr63@drexel.edu