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Master's & PhD Thesis Showcase


Master's Thesis


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Graduating Student, Advisor & Thesis Title

Development of CF-PEKK Composite Bone Plates via 3D Printing and Pressing for Void Reduction and Improved Mechanical Strength




Point-of-Care Additive Fused Filament Manufacturing of Patient-Specific Triflange Acetabular (TA) Reconstruction Implants




Magnetically Levitated Axial Flow Blood Pump for Pediatric Total Artificial Heart




Statistical Shape Modeling of Pelvic Anatomy: Design Envelope for Future Acetabular Implant Reconstructions and Statistical Shape Model Based on 15th-90th Percentile Ranges of Male and Female CT Scans




Identifying Neurophysiological Biomarkers Derived From fNIRS To Quantify Cognitive Workload During a UAS Mission




Investigating Eye Tracking Features in a Machine Learning Classifier To Assess Cognitive Workload During Simulation Based Training




3D-Printing at the Point-of-Care: Patient-Specific PEKK Ankle Fusion Implants for Diabetic Patients




Development of Finite Element Models of Maternal Pelvis, Fetus and Brachial Plexus




Using Supramolecular Chemistry To Develop Injectable Hydrogel Composites for Multi-Drug Delivery




Design of “Armored” Lipid-Based Nanoparticles for Prolonged Drug Circulation via Complement Pathway Attenuation




Aqueous CdSe Quantum Dot Molecular Beacon for RNA Detection




Exploring Biokinetics of Metal-Ion Release in Total Knee Arthroplasty: A Modeling Approach




Characterizing Aware and Unaware Vehicle Occupant Responses During Sled-Simulated Evasive Swerving: The Effect of Age and Maneuver Duration




Developing Mutant KRAS Targeted Vaccines for Pancreatic Cancer Interception




Combining Systems Biology Markup Language (SBML) Models in the Context of Cellular Aging Mechanisms




Mitochondrial Sequencing and Single-Cell RNA Sequencing Combination: A Promising Technique To Effectively Understand the Cell Dynamics in Breast Cancer




Hydrogel Scaffold for Neural Stem Cell Transplantation in Spinal Cord Injuries




Evaluation of Cognitive Function Using Time-Domain Optical Neuroimaging




Prediction of ADHD in Adolescents Utilizing fMRI-Based Individual Cortical Thickness Measurements




Development of a Finite Element Model of the Thoracic and Lumbar Spine with Ribs for Idiopathic Early Onset Scoliosis (EOS)




Acoustic Coupling Pads for the Control of Ultrasound Neuromodulation Exposure




Development and Characterization of Covalently Crosslinked Hydrogels for Use in Geometrically Tunable Blood Shunts




Local Delivery of Polycations From a Hydrogel Scaffold for Treating Spinal Cord Injury




A Pipeline for the Creation of Biophysically Realistic Multicompartment Models of Drosophila Melanogaster Descending Neurons (MDN)




Implementation of a Home-Use Virtual Environment Brain-Computer Interface (BCI) for People with ALS Using Different Facial Stimuli




Quantifying Lung, Diaphragm, and Thoracospinal Radiographic Parameters to Predict Lung Volume and Function in Pediatric Normative and Early Onset Scoliosis Subjects




Development of a Next Generation Human Induced Pluripotent Stem Cell-derived CNS Model for the Study of Tauopathy




Simeon Kofman, Master’s Candidate
School of Biomedical Engineering, Science and Health Systems
Drexel University

Advisors:
Liang Oscar Qiang, MD, PhD
Assistant Professor
Department of Neurobiology and Anatomy
Drexel University College of Medicine

Fred Allen, PhD
Teaching Professor
Associate Dean for Undergraduate Education
School of Biomedical Engineering, Science and Health Systems
Drexel University

Investigating the Performance of Sensor-driven Biometrics in the Assessment of Cognitive Workload




Emma Katherine MacNeil, Master's Candidate
School of Biomedical Engineering, Science and Health Systems
Drexel University

Advisor:
Kurtulus Izzetoglu, PhD
Associate Professor
School of Biomedical Engineering, Science and Health Systems
Drexel University

The Role of DIPs and Dprs in Synaptic Connection Specificity




Pratishtha Guckhool, Master's Candidate
School of Biomedical Engineering, Science and Health Systems
Drexel University

Advisor:
Catherine von Reyn, PhD
Assistant Professor
School of Biomedical Engineering, Science and Health Systems
Drexel University

Identification of Astrocyte Subtypes in the Drosophila Melanogaster Visual System




Jillian Clare Saunders, Master's Candidate
School of Biomedical Engineering, Science and Health Systems
Drexel University

Advisors:
Catherine von Reyn, PhD
Assistant Professor
School of Biomedical Engineering, Science and Health Systems
Drexel University

Denise Garcia, PhD
Associate Professor
Department of Biology
College of Arts and Sciences
Drexel University

Mathematical Dynamic Modeling (MADYMO) of Shoulder Dystocia and Delivery Maneuvers




Joy Anita Iaconianni, Master's Candidate
School of Biomedical Engineering, Science and Health Systems
Drexel University

Advisors:
Sriram Balasubramanian, PhD
Associate Professor
School of Biomedical Engineering, Science and Health Systems
Drexel University

Anita Singh, PhD
Chair of Biomedical Engineering
Associate Professor
Department of Biomedical Engineering
School of Engineering
Widener University

Photoresponsive Hydrogels Enable Geometrically Tunable Blood Shunts for Pediatric Use




Victor Mishin, Master's Candidate
School of Biomedical Engineering, Science and Health Systems
Drexel University

Advisors:
Christopher B. Rodell, PhD
Assistant Professor
School of Biomedical Engineering, Science and Health Systems
Drexel University

Amy L. Throckmorton, PhD
Associate Professor
School of Biomedical Engineering, Science and Health Systems
Drexel University

Investigating Biomechanical Properties and Structural Changes Post-Stretch in Neonatal Brachial Plexus




Virginia Orozco, PhD Candidate
School of Biomedical Engineering, Science and Health Systems
Drexel University

Advisors:
Sriram Balasubramanian, PhD
Associate Professor
School of Biomedical Engineering, Science and Health Systems
Drexel University

Anita Singh, PhD
Chair of Biomedical Engineering
Associate Professor
Department of Biomedical Engineering
School of Engineering
Widener University

Exploring the Responses of Acute Aortic Regurgitation (AR) Through the Design of a Novel Benchtop Physiological Model




Alison Kane, Master's Candidate
School of Biomedical Engineering, Science and Health Systems
Drexel University

Advisors:
Janarthanan (Janar) Sathananthan, BHB, MBChB, MPH, FRACP
Interventional and Structural Cardiologist
University of British Columbia (UBC)
St Paul’s Hospital and Vancouver General Hospital

Amy Throckmorton, PhD
Associate Professor
School of Biomedical Engineering, Science and Health Systems
Drexel University

PhD Thesis


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Graduating Student, Advisor & Thesis Title

Investigating Biomechanical Properties and Structural Changes Post-Stretch in the Neonatal Brachial Plexus




Development of Novel Polymer Ultrasound Contrast Agents Incorporating Nested Carbon Nanodots




Alternative Lengthening of Telomeres in Cancer




Mechanism of Cholesterol-Induced Impairment of Store-Operated Calcium Entry in Endothelial Cells




Development of Porous Swelling Copolymeric Bone Anchor for Orthopedic Applications




Predicting Failure of Non-Invasive Ventilation in Children with a Risk Stratification Model




Macrophage-Targeted Therapeutics To Attenuate the Development of Ischemic Heart Failure




Controlling Inflammation To Promote Tissue Regeneration




Developing Ultrasound Contrast Agents To Deliver siRNA to Spinal Cord Injury




Characterization of Genomic Regions for Improved Reference Genomes Using Optical Mapping (OM) and Sequencing Technologies




Automated Methods for Clustering, Clinical Indices Prediction, and Vertebrae and Lung Segmentation in Early Onset Scoliosis (EOS) Patients




Proteogenomic Discovery of Immunotherapeutic Targets in Cancer: Focus on Rhabdomyosarcoma




Evaluation of Chimeric Antigen Receptor Design To Identify Affinity and Spatial Binding Requirements for Optimal T Cell Effector Function




Characterizing Pharmacokinetic-Pharmacodynamic Relationships of VSV-GP




Development of a Platform Technology To Impart Immunomodulatory Activity to Complex Biomaterials




Single Molecule Telomere Length Measurement and Its Application in Investigation of ALT




Interaction of Lipid Nanoparticles with Pulmonary Innate Immune Cells in the Context of Acute Respiratory Distress Syndrome (ARDS)




Design of Point-of-Care Ultrasound Device and Applicator to be Used in an at-Home Setting – A Holistic Approach




Understanding and Tuning Macrophage Phenotype in Volumetric Muscle Loss (VML) Injury




Type V Collagen Orchestrates the Initial Matrix Templating in Developing Articular Cartilage and Meniscus




An Integrated, Scalable Platform for rAAV Vector Development Designed for Translational Success




Development and Clinical Application of an Arduino-based Functional Near Infrared Spectroscopy (fNIRS)




Detecting Respiratory Infection Causing Viruses Using Piezoelectric Plate Sensors in Thirty Minutes Without Gene Isolation and Amplification




Neuroadaptive Training Approaches To Enhance Skill Acquisition in Flight Simulators




Ultrasound Nano-Scale Phase-Change Contrast Agents for Hepatocellular Carcinoma Radiosensitization




A Multiscale Computational Platform in the Design of a Geometrically Tunable Blood Shunt




Investigation of Cerebrovascular Reactivity Using Hypercapnia and Optical Brain Imaging




Multi-omics Characterization of the Loss of Transcriptomic Modulators BAP1 and SOX10 in Uveal and Cutaneous Melanomas




Regulatory Roles of Fibril-Forming Collagens in Cartilaginous Tissue Biomechanics and Mechanobiology




Ultrasound-Sensitive Microbubble Approaches for Overcoming Tumor Hypoxia in Head and Neck Squamous Cell Carcinoma




A Single-Molecule DNA Analysis Device for Optical Mapping and Sequencing




Collagen Nanoyarns: Hierarchical Three-Dimensional Biomaterial Constructs for Tendon Fiber Reconstruction




Understanding Molecular Differences Between Healing Outcomes in Tissue Repair and Regeneration




High Conjugation Efficiency CdPbS Near-infrared Molecular Probe Toward Intraoperative Breast Cancer Margin Assessment




Novel Integrated Pediatric Total Artificial Heart




Modulating Macrophage Phenotype for the Promotion of Angiogenesis in an Ischemic Environment




Development, Adaptation, and Stimulus-independent Neural Activity in a Sensorimotor Circuit in Drosophila Melanogaster




The Role of Endothelial Cell Morphology and Alignment in the Coordinated Regulation of AKT-mediated and Calcium-mediated eNOS Activation




Novel Integrated Pediatric Total Artificial Heart




Understanding the Biological Effects of Non-thermal, Non-cavitational Therapeutic Ultrasound in Chronic Wound Healing




Coordinated Regulation of Shear Stress-Induced Nitric Oxide Production by TRPC Channel-derived Calcium Fluxes and PKC Modulation in Endothelial Cells




Quantification of Variations in Thoracic Vertebral Morphology and Prediction of Curve Progression and Correction in Adolescent Idiopathic Scoliosis (AIS)




Circuits for Bilateral Looming Feature Integration in Drosophila




HyoJong Jang, PhD Candidate
School of Biomedical Engineering, Science and Health Systems
Drexel University

Advisor:
Catherine von Reyn, PhD
Assistant Professor
School of Biomedical Engineering, Science and Health Systems
Drexel University

Inactivation of HIV-1 and SARS-CoV-2 viruses by Targeting Metastable Virus Spike Proteins




Aakansha Nangarlia, PhD Candidate
School of Biomedical Engineering, Science and Health Systems
Drexel University

Advisors:
Irwin Chaiken, PhD
Professor of Biochemistry and Molecular Biology
College of Medicine
Drexel University

Ken Barbee, PhD
Professor, Senior Associate Dean, and Associate Dean for Research
School of Biomedical Engineering, Science and Health Systems
Drexel University

Understanding How Time and Memory Interact with Network Topology in Real-World Systems with Selected Applications




Adam George Craig, PhD Candidate
School of Biomedical Engineering, Science and Health Systems
Drexel University

Advisors:
Andres Kriete, PhD
Associate Dean for Academic Affairs
Teaching Professor
School of Biomedical Engineering, Science and Health Systems
Drexel University

Uri Hershberg, PhD
Associate Professor
Department of Human Biology
University of Haifa
School of Biomedical Engineering, Science and Health Systems
Drexel University

Development and Characterization of 3D Printed Porous Polyetheretherketone (PEEK) for Orthopaedic Applications




Hannah Spece, PhD Candidate
School of Biomedical Engineering, Science and Health Systems
Drexel University

Advisors:
Steven Kurtz, PhD
Research Professor
School of Biomedical Engineering, Science and Health Systems
Drexel University

Joseph Sarver, PhD
Teaching Professor
School of Biomedical Engineering, Science and Health Systems
Drexel University

Impact of HIV-1 Genetic Variation on Tat-RNA Binding, Anti-HIV-1 gRNA Design, and HIV-Associated Neurocognitive Impairment (NI)




Robert William Link, PhD Candidate
School of Biomedical Engineering, Science and Health Systems
Drexel University

Advisors:
Will Dampier, PhD
Assistant Professor
Department of Microbiology and Immunology
College of Medicine
Drexel University

Brian Wigdahl, PhD
Professor and Chair
Department of Microbiology and Immunology
Director
Institute for Molecular Medicine and Infectious Disease
Drexel University College of Medicine