Brian Lee, PhD

Associate Professor, Department of Epidemiology and Biostatistics; Research Fellow, A.J. Drexel Autism Institute

Lee's research interests include the epidemiology of neurological development, maintenance and decline.  Current topics include prenatal environmental exposures and autism risk; neighborhoods and psychosocial "stress" in the cognitive decline of older adults; lead toxicity and white matter health; gene-environment interaction; maternal antibody exposure in utero and fetal outcomes.

For news media inquiries, contact Greg Richter at gdr33@drexel.edu or 215.895.2617.

In The News

Is Tylenol Safe for Children?
Brian Lee, PhD, a professor in the Dornsife School of Public Health, was quoted in a Sept. 29 JAMA Q&A article and Sept. 30 in Scientific American, about Lee’s role as senior author on a study that found no increased risk in autism, ADHD, or intellectual disabilities in the children of women who used acetaminophen during pregnancy. Lee was also a guest on the Sept. 29 Public Health On Call podcast to talk about the study. The research was also mentioned in a Sept. 26 Valigia Blu (Italy) story.
Is Tylenol Use During Pregnancy Connected To Autism?
Brian Lee, PhD, a professor in the Dornsife School of Public Health, was quoted in many stories nationwide about the debate over whether there is a link between acetaminophen and development of autism. Coverage included Sept. 23 on BBC World Service, La Presse (France) and KOKI (Fox23 Tulsa, OK), Sept. 25 in Rolling Stone, Sept. 22 stories on WMTW (ABC Portland, ME) and KYW-TV CBS3 and in Managed Healthcare Executive, and Sept. 26 in Science Friday. A Sept. 22 Hearst news segment featuring Lee ran on WVTM 13 (NBCBirmingham, AL), among other stations. Lee co-authored a Sept. 24 article in The Conversation about co-authoring a study finding that acetaminophen is not linked to autism. Lee was also quoted in articles on Sept. 25 in SF Gate and Very Well Health about recent Tylenol and autism claims and CBC (Canada) about whether leucovorin is a possible autism treatment.
The Science Behind the Correlation Between Autism and Tylenol
Brian Lee, PhD, a professor in the Dornsife School of Public Health, was quoted in dozens of stories nationwide about the debate over whether there is a link between acetaminophen and development of autism. Lee is senior author on a notable study in JAMA, the Journal of the American Medical Association, on the topic. Stories included the Sept. 23 episodes of NPR’s “Morning Edition,” and WHYY’s "Studio 2," and a Scripps News segment that ran on local news affiliates across the country. He was also interviewed in a Sept. 22 NBC News segment that ran on NBC stations nationwide. He was quoted in Sept. 23 stories in TIME magazine, two pieces on NBC’s TODAY, WebMD, The Spokesman Review (Spokane, Washington), and a KFF Health News piece that was republished by CBS News, ABC News, MedPage Today and other outlets. On Sept. 23 he was also quoted in New York Times, Washington Post, Healio, Patch, Politifact, Factcheck.org, The Independent (UK), Arizona Republic, Chemical & Engineering News, The Transmitter, Deseret News (Salt Lake City), NPR Shots, STAT news and CBC (Canada) stories and news segments on WCAU (NBC-10), KSTU-TV (Fox-Salt Lake City), KSHB-TV (NBC-Kansas City, Missouri) KDFW-TV (Fox-Houston), W Radio (Columbia) and a Sept. 24 StateImpact Oklahoma segment.
Trump is Pushing Leucovorin as a Treatment For Autism. What Is It?
Matthew Lerner, PhD, an associate professor and life courses outcomes program leader in the A.J. Drexel Autism Institute and Brian Lee, PhD, a professor, both in the Dornsife School of Public Health, were quoted in a Sept. 22 Philadelphia Inquirer article about what the data shows about causes of autism. Lerner was also quoted in a Sept. 24 MIT Technology Review article about whether leucovorin could be a treatment for autism.
What Research Shows About Tylenol and Autism
Brian Lee, PhD, a professor in the Dornsife School of Public Health, was featured in a Sept. 8 CBS News segment and quoted in a Sept. 9 Parents article about the latest research on acetaminophen use by pregnant mothers and whether there is a link from that or other medications to autism. A Sept. 5 NBC News story quoting Lee also ran on many NBC stations nationwide, including KNTV-TV (NBC-San Jose, California) and KXAS-TV (NBC-Dallas, Texas), among other outlets.
Debate Flares Over an Unproven Link Between Tylenol and Autism
Brian Lee, PhD, a professor in the Dornsife School of Public Health, was quoted in articles Sept. 5 in The New York Times and NBC News and Sept. 6 in Daily Beast about the body of knowledge on research about acetaminophen use by pregnant mothers and whether there is a link from that or other medications to autism.
Giant Study Questions Link Between Autism and Maternal Health
Brian Lee, PhD, a professor in the Dornsife School of Public Health, was quoted in a Jan. 31 Science article about new data on maternal health and autism in children.
Acetaminophen Use in Pregnancy Does Not Increase Risk of Autism or ADHD, Study Finds
Brian Lee, PhD, an associate professor in the Dornsife School of Public Health, was quoted in an April 15 Parents magazine article about Lee’s recently published study finding no link between acetaminophen use in pregnancy and increased risk of autism or ADHD.

Related Articles

medicine during pregnancy Children Exposed to Antiseizure Meds During Pregnancy Face Neurodevelopmental Risks, Drexel Study Finds
Children born to mothers who take antiseizure medications to manage seizures and psychiatric conditions during pregnancy may face increased risks of neurodevelopmental conditions, according to new data from researchers at Drexel’s Dornsife School of Public Health.
No Link Between Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability, Says Large Sibling Study from Drexel University and Sweden’s Karolinska Institutet
In the largest study to date on the subject, researchers found no evidence to support a causal link between acetaminophen use during pregnancy and increased risk of autism, ADHD and intellectual disability in children. The findings, using data from a nationwide cohort of over 2.4 million children born in Sweden, including siblings not exposed to the drug before birth, were published today in the Journal of the American Medical Association (JAMA) from researchers at Drexel’s Dornsife School of Public Health and Karolinska Institutet of Sweden.
A spilled bottle of multivitamins Multivitamin Use During Pregnancy Linked to Lower Risk of Autism With Intellectual Disability
Taking a multivitamin during pregnancy was linked to a 30 percent decrease in risk of a child developing autism with an intellectual disorder, according to a new Drexel University study.
A pregnant woman in a blue dress holding her stomach. Antidepressant Use in Pregnant Women Linked to Small Increase in Autism
Antidepressant use in pregnant women was linked to increased cases of autism in their children, though the trend actually appeared to be relatively small, effecting just 2 percent of children with diagnoses.
Students studying from binders at a table. Parental Depression Negatively Affects Children’s School Performance
A study led by Drexel researchers found that parental depression was associated with diminished school performance in children.
Google search trends for the term "autism" from 2010 through 2014, showing peaks in searches in April of each year. Awareness Month Spurs Web Searches for Autism
Autism Awareness Month each April brings blue lights and blue ribbons out to shine in many communities – but does it actually lead to increased autism awareness? According to a new analysis of web search trends by researchers at Drexel University, it does appear to drive an increase in Google searches for autism – by a third over searches in March in recent years.
Autism rates were about double in children born to mothers who took an SSRI during pregnancy, compared to children of mothers who didn't -- but overall rates were extremely low in both groups. In Utero Exposure to Antidepressants May Influence Autism Risk
A new study from researchers at Drexel University adds evidence that using common antidepressant medications during pregnancy may contribute to a higher risk of autism spectrum disorders (ASD) in children, although this risk is still very small.
Generalized additive model estimates of probability of ASD by maternal and paternal age (years) in the Stockholm Youth Cohort. The 95% CIs are indicated by dashed lines. Based on Idring et al., International Journal of Epidemiology Child's Autism Risk Accelerates with Mother's Age Over 30
A recent study from researchers from the Drexel University School of Public Health in Philadelphia and Karolinska Institute in Sweden provides more insight into how the higher risk of having a child with an autism spectrum disorder (ASD) among older parents varies between mothers’ and fathers’ ages, and found that the risk of having a child with both ASD and intellectual disability is larger for older parents.