Ramesh Raghupathi, PhD
Professor, Department of Neurobiology and Anatomy, College of Medicine, Drexel University

 

Pediatric brain trauma is a leading cause of long-term death and disability in infants and children under the age of 4. Despite advances in acute critical care, there are no treatment strategies aimed at limiting the long term behavioral deficits that these children face as they age into adolescence and adulthood. One potential target for treatment is inflammation within the brain as a consequence of the injury. However, the intersection between development and progression of the injury can potentially limit the efficacy of these strategies. Data presented will demonstrate the pros and cons of interventions focused on limiting brain inflammation.