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Dr. Chris Rodell Receives an NIH Grant to Develop Supramolecular Delivery Strategies to Understand & Exploit Synergies in Immunoregenerative Medicine

July 18, 2022

Dr. Chris Rodell, assistant professor in the School of Biomedical Engineering, Science and Health Systems, received a 5-year $1.9M NIH National Institute of General Medical Sciences (NIGMS) R35 Maximizing Investigators' Research Award (MIRA) for the project titled, “Designing Supramolecular Delivery Strategies to Understand and Exploit Synergies in Immunoregenerative Medicine.” It remains unclear why some tissue injuries regenerate and heal while others fibrose and scar. It is evident, however, that the inflammatory response underlies these divergent outcomes. The $1.9M in funding from NIGMS will support three critical project areas in the Rodell lab that explore therapeutic drug delivery in the context of organ injury. Their projects examine how cell-targeted therapies alter monocyte-macrophage crosstalk, how amplification of early inflammation alters long-term tissue healing, and the ability of biotherapeutics to mitigate systemic inflammation that results in multi-organ damage.