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Department of Epidemiology and Biostatistics Dissertation Defense: Chioma Uzoigwe

Monday, June 1, 2026

10:30 AM-11:30 AM

Department of Epidemiology and Biostatistics Dissertation Defense

Chioma Uzoigwe, MPH, will present "Clinical Effects of Compliance with Antidepressants on Glycemic Control in Adults Treated for Comorbid Type 2 Diabetes Mellitus and Major Depressive Disorder."

Dissertation committee: Longjian Liu, MD, PhD (Advisor), Felice Le-Scherban, PhD, Christopher Blanchette, PhD (external), Deeptha Sukumar, PhD, Agus Surachman, PhD

Adults with type 2 diabetes mellitus (T2DM) experience disproportionately high rates of comorbid major depressive disorder (MDD), a combination associated with poorer self-management, reduced medication adherence and worse clinical outcomes. Despite the clinical importance of treating both conditions, evidence regarding how antidepressant use and adherence behaviors influence glycemic control remains limited and methodologically inconsistent.

This dissertation examined the real-world relationship between antidepressant use and glycemic control among adults with treated T2DM and comorbid MDD across three aims: (1) characterizing baseline differences between antidepressant initiators and non-initiators, (2) estimating the association between antidepressant initiation and glycemic control with explicit attention to compliance and persistence, and (3) formally evaluating whether compliance and persistence mediate the antidepressant-glycemic control relationship.

Chioma Uzoigwe is a senior real-world evidence leader with over 17 years of experience spanning health economics, outcomes research, and evidence generation across U.S. and global markets. She currently serves as Director of Real World Evidence at Novo Nordisk, Inc., where she leads research delivering high-quality, decision-ready evidence across multiple therapeutic areas, including diabetes, cardiovascular disease, liver health, and Alzheimer's disease.

Chioma holds a Bachelor of Arts in Psychology from Stanford University and a Master of Public Health in Epidemiology from the University of Medicine and Dentistry of New Jersey. She is completing her Doctor of Philosophy in Epidemiology at Drexel University, where her dissertation examines the clinical effects of antidepressant compliance on glycemic control in adults with comorbid type 2 diabetes and major depressive disorder.

Her research portfolio includes over a dozen peer-reviewed publications and more than 30 conference presentations at leading scientific meetings, including the American Diabetes Association, ISPOR, and the American College of Cardiology. She is a two-time recipient of Novo Nordisk's CMR Leadership and Drive Change Awards and was selected as one of two nominees to represent Novo Nordisk in the Women of Color in Pharma Global Leadership Accelerator in 2024.

Chioma is passionate about mentoring talent, advancing health equity in real-world research, and building evidence that connects data to the patients behind it.

Zoom link

Contact Information

Nancy Colon-Anderson
nanderson@drexel.edu

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Location

Nesbitt Hall, Room 751 and online via Zoom

Audience

  • Everyone