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Jeff Barrett

Head Quantitative Sciences at Bill & Melinda Gates Medical Research Institute

Dr. Jeff Barrett is Head Quantitative Sciences at Bill & Melinda Gates Medical Research Institute. Accountable for leading The Institute in drug and vaccine development through the implementation of model-based drug development and employing PK/PD modeling, statistics, and clinical trial simulations. The role also provides support for other Institute efforts requiring development/quantitative support including vector control, diagnostics, and product development. Participates in the decision making and overall operations of the Institute and helps to build the new organization including modeling and driving the desired culture, hiring individuals with the talent, drive, and skills to achieve the Institute mission, and providing input on systems and the overall operating model. Building and managing a team that is responsible for establishing the modeling, biostatistics, bioinformatics, and DMPK function for the Institute.

Jeff spent the previous 10+ years at the University of Pennsylvania where he was Professor, Pediatrics and Director, Laboratory for Applied PK/PD at the Children's Hospital of Pennsylvania (CHOP). His academic career was highlighted by sustained NIH support for pharmacometric research across numerous therapeutic areas in adult and pediatric populations. He continues to serve as an Adjunct Professor of Pediatrics at the U Penn School of Medicine and is the course director for two courses in the regulatory sciences track in the Masters in Translational Research program. Prior to tenure at U Penn / CHOP, Jeff spent 13 years in the pharmaceutical industry. Jeff received his B.S. in Chemical Engineering from Drexel University and Ph.D. in Pharmacokinetics from University of Michigan. He is a fellow of ACCP and AAPS and the recipient of numerous honors including ACCP awards for Young Investigator (2002) and Mentorship in Clinical Pharmacology (2007) and the AAPS Award in Clinical Pharmacology and Translational Research (2011). Dr. Barrett was awarded for Exceptional Innovation and Advancing the Discipline of Pharmacometrics at the International Society for Pharmacometrics (2013) and was inducted into the Drexel University College of Engineering's Circle of Distinction in 2015. He has co-authored over 150 manuscripts and has given over 125 invited lectures on PK/PD, clinical pharmacology and pharmacometrics. He serves on the Editorial Boards of the Journal of Pharmacokinetics and Pharmacodynamics and the ASCPT Pharmacometrics & Systems Pharmacology Journal and is the co-Specialty Chief Editor of Frontiers in Obstetric and Pediatric Pharmacology.