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Manuel Seman-Senderos, PhD

Assistant Teaching Professor
Department of Biology
Office: PISB 221


  • PhD, Cellular and Molecular Medicine, Johns Hopkins University School of Medicine 2021
  • BSc, Basic Biomedical Research, UNAM 2012

Curriculum Vitae:

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Research Interests:

  • Cell Biology
  • Genetics
  • History of Science
  • Synthetic Biology
  • Drug Discovery


Manuel Alejandro Seman Senderos is an Assistant Teaching Professor in the Department of Biology. He previously earned his PhD at the Johns Hopkins University School of Medicine under the mentorship of Dr. Hal Dietz studying fibrotic diseases. His research focus was cell biology processes gone awry in disease and the use of genetic tools in order to find and validate new therapeutic targets. As a professor, his main interest is to make abstract concepts tangible by highlighting the experimental methods as well as the historical context behind specific breakthroughs.

Selected Publications:

Russel Gould, Hamza Aziz, Courtney Woods, Manuel Alejandro Semán-Senderos et al.OBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm. (2019) Nature Genetics 51: 42-50.

James Beckett, David Kim, Varun Nagpal, Manuel Alejandro Semán-Senderos et al. Calpain 9 as a Novel Therapeutic Target in TGF-Induced Mesenchymal Transition and Fibrosis. (2019) Science Translational Medicine 11(501): 1-15.