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Joe Foley

Joe P. Foley, PhD

Department Head
Department of Chemistry
Office: Disque Hall 306
Phone: 215.895.6218
Fax: 215.895.1702


  • PhD, University of Florida, 1983
  • BS, Centre College of Kentucky, 1978

Curriculum Vitae:

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Research Interests:

  • Analytical Chemistry
  • Separation Science
  • Ultra-High Performance Liquid Chromatography
  • Tandem Column Liquid Chromatography
  • Two-Dimensional Liquid Chromatography
  • Capillary and Microchip Electrophoresis
  • Electrokinetic Chromatography


Joe Foley is Professor and Department Head of Chemistry at Drexel University. He earned a B.S in Chemistry and Chemical Physics from Centre College of Kentucky and his Ph.D. in Chemistry from the University of Florida under the mentorship of John Dorsey. He conducted research at National Institute for Standards and Technology (NIST) for 2 years as a National Research Council Postdoctoral Fellow. While on sabbatical in 2006-2007 he was a Visiting Professor of Chemistry in the Institute of Pharmaceutical Technology at the University of Frankfurt (Germany), and during 2015-2016 he was a Visiting Fellow in the Australian Centre for Research on Separation Science (ACROSS) at the University of Tasmania in Hobart. He received the Eastern Analytical Symposium (EAS) Award for Outstanding Achievements in Separation Science in 2020 and the Chromatography Forum of Delaware Valley Award in 2021.

Joe's research interests are in the fundamental and applied aspects of analytical chemistry and separation science, and in addition to giving over 100 invited presentations he has authored or co-authored over 125 articles, book chapters, reviews, and one patent pertaining to pressure- and voltage-driven condensed-phase separations (U/HPLC, CE/EKC, SFC) while mentoring 4 postdocs/visiting scientists, 39 Ph.D. students (5 in progress), 11 M.S. students, and 25 undergraduates. A highly-cited author, several equations from his publications pertaining to chromatographic figures of merit, electrokinetic chromatography, and two-dimensional liquid chromatography have appeared in undergraduate textbooks and/or graduate monographs. He currently serves on the editorial boards of several peer-reviewed journals including Bioanalysis, Chromatographia, Electrophoresis, and Separations, having previously served on the boards of Analytical Communications, The Analyst, and the Journal of Microcolumn Separations. A long-time ad hoc reviewer for NSF and NIH, Joe is a lifetime member of the Chromatography Forum of the Delaware Valley (CFDV) and has twice served as Program Chair and President.

Selected Publications:

  • M. E. Marrazzo, J. P. Foley, (2023), Tandem-Column High Performance Liquid Chromatography Separation of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). Chromatographia, 86 (11-12), 743-750.
  • Liu, Z.; Y. Zhou,; Q. Wang, J. P. Foley, D. R. Stoll, J. G. Shackman, (2023), Development of tandem-column liquid chromatographic methods for pharmaceutical compounds using simulations based on hydrophobic subtraction model parameters. J. Chromatogr. A, 1695, 463925.
  • Z. Liu, J.P. Foley, (2022), Are two liquid chromatography columns in tandem better than one?: Answers from the hydrophobic subtraction model, J. Chromatogr. A, 1668, 462890.
  • L. Li, J.P. Foley, R. Helmy, (2019), Simultaneous separation of small interfering RNA and lipids using ion-pair reversed-phase liquid chromatography, J. Chromatogr. A, 1601, 145-154.
  • L. Ranjbar, M. Talebi, P.R. Haddad, S.H. Park, J.M. Cabot, M. Zhang, P. Smejkal, J.P. Foley, M.C. Breadmore, (2017), In Silico Screening of Two-Dimensional Separation Selectivity for Ion Chromatography × Capillary Electrophoresis Separation of Low-Molecular-Mass Organic Acids, Anal. Chem., 89, 8808-8815.
  • J.P. Foley, D.M. Blackney, E.J. Ennis, (2017), Peak capacity and peak capacity per unit time in capillary and microchip zone electrophoresis, J. Chromatogr. A, 1523, 80-89.
  • A. Socia, J.P. Foley, (2014), Sequential elution liquid chromatography can significantly increase the probability of a successful separation by simultaneously increasing the peak capacity and reducing the separation disorder, J. Chromatogr. A, 1324 36-48.
  • M. Biba, E. Jiang, B. Mao, D. Zewge, J.P. Foley, C.J. Welch, (2013), Factors influencing the separation of oligonucleotides using reversed-phase/ion-exchange mixed-mode high performance liquid chromatography columns, J. Chromatogr. A, 1304, 69-77.
  • T.J. McCormick, J.P. Foley, C.M. Riley, D.K. Lloyd, (2000), The effect of stationary-phase pore size on retention behavior in micellar liquid chromatography, Anal. Chem., 72, 294-301.
  • R.E. Murphy, M.R. Schure, J.P. Foley, (1998), Effect of Sampling Rate on Resolution in Comprehensive Two-Dimensional Liquid Chromatography, Anal. Chem., 70, 1585-1594. (journal cover).
  • M. Hong, B.S. Weekley, S.J. Grieb, J.P. Foley, (1998), Electrokinetic Chromatography Using Thermodynamically-Stable Vesicles and Mixed Micelles Formed from Oppositely Charged Surfactants, Anal. Chem., 70, 1394-1403.
  • J.P. Foley, (1991), Resolution Equations for Column Chromatography, Analyst, 116, 1275-1279.
  • J.P. Foley, (1990), Optimization of Micellar Electrokinetic Chromatography, Anal. Chem., 62, 1302-1308.
  • J.P. Foley, W.E. May, (1987), Optimization of Secondary Chemical Equilibria in Liquid Chromatography: Theory and Verification, Anal. Chem., 59, 102-109.
  • J.P. Foley, J.G. Dorsey, (1983), Equations for Calculation of Chromatographic Figures of Merit for Ideal and Skewed Peaks, Anal. Chem., 55, 730-737.

Academic Details:

Graduate Program Faculty Member

*Only Graduate Program Faculty members can mentor students.