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Jerome Ricard, PhD

Jerome Ricard, PhD

Assistant Research Professor
Department of Biology
Office: PISB 413
jjr325@drexel.edu
Phone: 215.571.3785

Education:

  • PhD, Biology, Joseph Fourier University, Grenoble (France), 1998

Curriculum Vitae:

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Research Interests:

  • Ephrins
  • Spinal cord injury
  • Neuroinflammation
  • Cell death
  • Dependence receptors
  • Pain

Bio:

Dr. Jerome Ricard, an Assistant Research Professor in the Department of Biology, studies neuroscience in Drexel Professor John Bethea’s laboratory. The laboratory explores neuroinflammation and pain, examined in various models such as spinal cord injury, peripheral neuropathy, or multiple sclerosis.

The team has over 20 years of experience with spinal cord injury, having worked at the Miami Project to Cure Paralysis before coming to Drexel in 2014. Dr. Ricard has also worked on the role of Eph receptors on neurogenesis in the brain and the control of cell death.

Ricard enjoys teaching and training students and has mentored one master’s student, four undergraduate STAR scholars at Drexel, and several volunteer undergraduates in the laboratory. The subjects he has been teaching in the classroom include neuroscience, development biology, genetics, and cellular and molecular biology. He has also served as a faculty mentor for Biology seniors writing proposals for their capstone course.

Selected Publications:

  • Blumenthal, G. H., B. Nandakumar, A. K. Schnider, M. R. Detloff, J. Ricard, J. R. Bethea and K. A. Moxon (2021). "Modelling at-level allodynia after mid-thoracic contusion in the rat." Eur. J. Pain 25(4): 801-816.
  • Gerald, M. J., V. Bracchi-Ricard, J. Ricard, R. Fischer, B. Nandakumar, G. H. Blumenthal, R. Williams, R. E. Kontermann, K. Pfizenmaier, K. A. Moxon and J. R. Bethea (2019). "Continuous infusion of an agonist of the tumor necrosis factor receptor 2 in the spinal cord improves recovery after traumatic contusive injury." CNS Neurosci. Ther. 25(8): 884-893.
  • Mironets, E., P. Osei-Owusu, V. Bracchi-Ricard, R. Fischer, E. A. Owens, J. Ricard, D. Wu, T. Saltos, E. Collyer, S. Hou, J. R. Bethea and V. J. Tom (2018). "Soluble TNFalpha signaling within the spinal Cord contributes to the development of autonomic dysreflexia and ensuing vascular and immune dysfunction after spinal cord injury." J. Neurosci. 38(17): 4146-4162.
  • Tsenkina, Y.*, J. Ricard*, E. Runko, M. M. Quiala-Acosta, J. Mier and D. J. Liebl (2015). "EphB3 receptors function as dependence receptors to mediate oligodendrocyte cell death following contusive spinal cord injury." Cell Death Dis. 6: e1922.
  • Novrup, H. G., V. Bracchi-Ricard, D. G. Ellman, J. Ricard, A. Jain, E. Runko, L. Lyck, M. Yli-Karjanmaa, D. E. Szymkowski, D. D. Pearse, K. L. Lambertsen and J. R. Bethea (2014). "Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice." J. Neuroinflammation 11: 159.
  • Theus, M. H., J. Ricard, S. J. Glass, L. G. Travieso and D. J. Liebl (2014). "EphrinB3 blocks EphB3 dependence receptor functions to prevent cell death following traumatic brain injury." Cell Death Dis. 5: e1207.
  • Bracchi-Ricard, V., K. L. Lambertsen, J. Ricard, L. Nathanson, S. Karmally, J. Johnstone, D. G. Ellman, B. Frydel, D. M. McTigue and J. R. Bethea (2013). "Inhibition of astroglial NF-kappaB enhances oligodendrogenesis following spinal cord injury." J. Neuroinflammation 10: 92.
  • Nelersa, C. M., H. Barreras, E. Runko, J. Ricard, Y. Shi, S. J. Glass, J. L. Bixby, V. P. Lemmon and D. J. Liebl (2012). "High-content analysis of proapoptotic EphA4 dependence receptor functions using small-molecule libraries." J. Biomol. Screen. 17(6): 785-795.
  • Theus, M. H., J. Ricard and D. J. Liebl (2012). "Reproducible expansion and characterization of mouse neural stem/progenitor cells in adherent cultures derived from the adult subventricular zone." Curr. Protoc. Stem Cell Biol. Chapter 2: Unit 2D 8.
  • del Valle, K., M. H. Theus, J. R. Bethea, D. J. Liebl and J. Ricard (2011). "Neural progenitors proliferation is inhibited by EphB3 in the developing subventricular zone." Int. J. Dev. Neurosci. 29(1): 9-14.
  • Theus, M. H., J. Ricard, J. R. Bethea and D. J. Liebl (2010). "EphB3 limits the expansion of neural progenitor cells in the subventricular zone by regulating p53 during homeostasis and following traumatic brain injury." Stem Cells 28(7): 1231-1242.
  • Furne, C.*, J. Ricard*, J. R. Cabrera, L. Pays, J. R. Bethea, P. Mehlen and D. J. Liebl (2009). "EphrinB3 is an anti-apoptotic ligand that inhibits the dependence receptor functions of EphA4 receptors during adult neurogenesis." Biochim. Biophys. Acta 1793(2): 231-238.
  • Ricard, J., J. Salinas, L. Garcia and D. J. Liebl (2006). "EphrinB3 regulates cell proliferation and survival in adult neurogenesis." Mol. Cell. Neurosci. 31(4): 713-722.
  • Ricard, J. and D. J. Liebl (2004). "Neurogenesis: is the adult stem cell young or old?" IUBMB Life 56(1): 1-6.
  • Fernandez-Valle, C., Y. Tang, J. Ricard, A. Rodenas-Ruano, A. Taylor, E. Hackler, J. Biggerstaff and J. Iacovelli (2002). "Paxillin binds schwannomin and regulates its density-dependent localization and effect on cell morphology." Nat. Genet. 31(4): 354-362.

*: co-first authors