Kari Lenhart, PhD

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Assistant Professor
Co-Director, Graduate Biology Program

Department of Biology

Office: PISB 420
kari.f.lenhart@drexel.edu
Phone: 215.895.6772

Additional Sites:

The Lenhart Lab
Niche-regulation of stem cell behaviors
Genetics and long-term live imaging
How somatic stem cells control germline stem cell (GSC) biology
How somatic cells regulate restoration of GSCs following stress
How soma-germline interactions are disrupted during tumorigenesis and during aging
How somatic cells differ between the testis and ovary, how these differences are maintained over time and what impact these differences have on the associated germline
How the niche controls stem cell behavior, which may have important implications for stem cell therapies, cancer treatments and ameliorating the effects of aging

Roach TV, Harsh S, Sainath R, Bach EA, and Lenhart KF. Conversion of somatic sex identity in the testis induces female-specific cellular behaviors in the soma and early oocyte specification in the germline. bioRxiv. 2024.
Roach TV and Lenhart KF. Mating-induced Ecdysone in the testis disrupts soma-germline contacts and stem cell cytokinesis. Development. 2024.
Lenhart KF, Capozzoli B and DiNardo S. Failure of stem cell cytokinesis with age due to diminished JAK/Stat activity. Current Biology. 2019.
Lenhart KF and DiNardo S. Somatic cell encystment promotes abscission in germline stem cells following a regulated block in cytokinesis. Developmental Cell. 2015.