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Biophysics Research

Biophysics Research: Brigita Urbanc, PhD

Research Areas in Biophysics

  • Dynamics of Biomolecules
  • Force Transduction in Muscle
  • Neurodegenerative Diseases
  • Phase Transitions in Biology
  • Protein Folding and Self-Assembly
  • Systems biology and bio-networks
  • Ultrafast Laser Spectroscopy

Faculty Conducting Research in Biophysics

Contact Specialization
Alexey Aprelev, PhD
Assistant Teaching Professor
Disque Hall 924
aprelev@drexel.edu
Luis Cruz Cruz
Associate Professor
Disque Hall 912
ccruz@physics.drexel.edu
Computational studies of confinement effects on the folding of amyloidogenic proteins, spatial correlations of neurons in the brain, firing dynamics of neuronal networks, fluid flow through porous media
Dr. Frank Ferrone
Professor
Disque Hall 922
fferrone@physics.drexel.edu
Experimental and theoretical protein dynamics, kinetics of biological self-assembly, including sickle cell and Alzheimer's disease, sickle cell testing and diagnostic devices
Brigita Urbanc
Associate Professor
Disque Hall 909
brigita@physics.drexel.edu
Computational and experimental biophysics of protein folding and assembly, relevant to Alzheimer's and Parkinson's disease; discrete molecular dynamics of coarse-grained protein and lipid models
Dr. Jian-Min Yuan
Professor
Disque Hall 819B
yuanjm@drexel.edu
Biophysics, protein folding/unfolding, protein aggregation, cellular signaling pathways, stochastic dynamics; chemical physics, reaction dyanmics, nonlinear dynamics, interaction of radiation with matter

Current Research Projects

Biophysics Facilities

  • Biomanipulation and Microscopy Laboratories: Four optical tables and six research grade microscopes are configured to perform microscopic spectroscopy and manipulation on solutions and individual cells. A spatial light modulator allows spatial patterns to be encoded on samples and explored; all microscopes are temperature-controlled with state-of-the-art cameras, including a 2,000 frame-per-second high-speed system. Each optical table is also equipped with high power lasers for photolysis or fluorescence spectroscopy.
  • Microfluidic attachments are available for use, and a small microfluidic fabrication facility has also been established.
  • The fluorescence microscope resolves fast biomolecular dynamics in living cells.
  • The Computational Biophysics Facility also includes two Beowulf clusters (44-node dual-core Xeon, 43-node dual quad-core Xeon [344 cores]), 24 TB RAID disk server, and 10 Linux workstations connected through a gigabit network.