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Longjian Liu, MD, PhD, MSc, FAHA

Associate Professor of Epidemiology and Biostatistics

Phone: 267.359.6049
College: Dornsife School of Public Health
Program: Epidemiology and Biostatistics, Center for Health Equality
Email: LL85@drexel.edu
CV: Download CV

Degrees

MD, Shanxi Medical University; MSc in Epidemiology, The University of London School of Hygiene and Tropical Medicine; PhD in Epidemiology, The University of Hong Kong; and MD Postdoctoral Fellow, The University of Arkansas for Medical Sciences

Bio

Dr. Longjian Liu is an associate professor of Epidemiology & Biostatistics, and the past Interim Chair of the Department of Environmental and Occupational Health at Drexel University School of Public Health. Prior to joining Drexel, Dr. Liu had training, teaching and research experience in leading universities of China, the United Kingdom, Japan, and the United States. Dr. Liu is a Fellow of the American Heart Association (FAHA).

Dr. Liu teaches Cardiovascular Disease Epidemiology and Prevention, and Epidemiology for Public Health Practice. Dr. Liu also led the course design and taught the online course, entitled “Certificate in Epidemiology and Biostatistics Principles and Methods for Public Health in the 21st Century”. Dr. Liu coauthored the chapter of Cardiovascular Disease Epidemiology for an APHA-published text entitled Chronic Disease Epidemiology and Control (3rd Ed., 2010). Dr. Liu’s teaching philosophy is Students First!

Dr. Liu’s research has focused on epidemiology of cardiovascular disease, diabetes mellitus, premature death, aging and diseases (cognitive and neurodegenerative disorders), and risk factors related to environmental pollution, toxicology, serum biomarkers (lipids and nutrients), medications, drug resistance, and environmental - drug interactions on disease control and prevention. Dr. Liu has research experience in working with several regional, national and international studies. He has over 60 articles published in peer-reviewed journals, with a total Impact Factor score more than 160. The key theories applied in his research are the integrated ecological models, chronic care model and disease preventable models. The overarching goal of his research is to translate research finding to health policy and practice of disease prevention. Four integrated themes are included in his research activities:

(1). Environmental Risk Factors of Cardiovascular Disease and Urban Health: Dr. Liu has involved in the World Health Organization (WHO) - Cardiovascular Disease and Alimentary Comparison (WHO-CARDIAC) Study, the WHO – World Health Surveys (WHS), and the Study on Global Ageing and Adult Health (SAGE). The goal of these studies is to examine environmental risk factors (built environmental, air pollution, healthcare system) and lifestyle-related risk factors for hypertension, heart disease, stroke and diabetes mellitus across nations. Dr. Liu is the Principal Investigator of Drexel (US) - SARI (China) research and Education project on Climate Change, Energy, Low-Carbon, and Urban Health Technology. 

(2). Biomarkers, Drug Resistance and Arterial Aging: Studies of determinants of hypertension, heart disease, stroke, diabetes mellitus, and the consequence of cognitive and neurodegenerative disorders in aging population. Dr. Liu is the Principal Investigator for the study of environmental (E) and drugs, and E - drugs interaction on the risk of heart disease in patients with diabetes mellitus and/or Chronic Kidney Disease. 

(3). Micronutrients, Fatty Acids and Healthy Aging: Studies of the impacts of micronutrients, fatty acids, oxidative stress and inflammation on metabolic disorders, arthrosclerosis and neurodegenerative disorders.

(4). Application of Advanced Analytic Techniques and Mining “Big Data”: Multivariate analysis, mining “big data”, and biological network analysis. Real-time disease risk surveillance and statistical predictive modeling using data from multiple hospitals’ electronic health records, such as Nationwide Inpatient Sample, and National Hospital Discharge Surveys, data from regional, national and international population-based health surveys.

Research Interests

  • Advanced Biostatistics and Epidemiology Applied in Health Insurance and claim Data Study
  • Cardiovascular and Diabetes Epidemiology and Prevention
  • Epidemiology and Biostatistics for Public Health Practice
  • Global Climate Change, Air Pollution and Urban Health
  • Hospital Electronic Health Record System and Health Outcomes Study
  • Pharmacoepidemiology and Pharmacovigilance
  • SAS, SPSS, and GIS  for large-scale complex survey data and spatial analysis

Publications

Jing Sun, Pooja Rangan, Srinidhi Subraya Bhat, and Longjian Liu: A Meta-Analysis of the Association between Helicobacter Pylori Infection and Risk of Coronary Heart Disease from Published Prospective Studies. Helicobacter, 2016 Feb:21(1):11-23. PMID: 25997465. PubMed

Longjian Liu, Ana E. Núṅez, Yuan An, Hui Liu, Ming Chen, Jixiang Ma, Edgar Y. Chou, Zhengming Chen, and Howard J. Eisen: Burden of Cardiovascular Disease among Multi-Racial and Ethnic Populations in the United States: An Update from the National Health Interview Surveys. Frontiers in Cardiovascular Medicine, 2014, 1:1-8. PMID: 26664859. PubMed

Longjian Liu and Ana E. Núñez: Multilevel and Urban Health Modeling of Risk Factors for Diabetes Mellitus: A New Insight to Public Health and Preventive Medicine. Advances in Preventive Medicine, 2014, 1-7. PMID 25431678. PubMed

Longjian Liu and Howard J Eisen: Epidemiology of heart failure and scope of the problem. Cardiology Clinics, 2014, 32(1):1-8. PMID: 24286574, (IMF: 1.25). PubMed

Longjian Liu, Katsuyuki Miura, Akira Fujiyoshi, Aya Kadota, Naoko Miyagawa, Yasuyuki Nakamura, Takayoshi Ohkubo, Akira Okayama, Tomonori Okamura, Hirotsugu Ueshima: Impact of Metabolic Syndrome on the Risk of Cardiovascular Disease Mortality in the United States and in Japan. American Journal of Cardiology, 2014, 113(1):84-89. PMID: 24169008. PubMed

Longjian Liu, Ana E Nunez, Xiaoping Yu, Xiaoyan Yin and Howard J. Eisen: Multilevel and Spatial-Time Trend Analyses of the Prevalence of Hypertension in a Large Urban City in the USA. Journal Urban Health 2013;(6):1053-63.PMID:23897041. PubMed

Longjian Liu, Yuan An, Ming Chen, Zuolu Liu, Xiaohua Hu, Edgar Chou and Howard J. Eisen: Trends in the prevalence of hospitalization attributable to hypertensive diseases among United States adults aged 35 and older from 1980 to 2007. American Journal of Cardiology 2013;112:694-699, PMID: 23726180. PubMed

Yong Long, Edward J. Gracely, Craig J. Newschaffer and Longjian Liu: Analysis of the prevalence of cardiovascular disease and associated risk factors for European-American and African-American populations in the state of Pennsylvania 2005-2009. American J Cardiology. 2013;111:68-72. PMID: 23040600. PubMed

Longjian Liu, Fuzhong Xue, Jixiang Ma, Marshal Ma, Yong Long, and Craig J. Newschaffer: Social Position and Chronic Conditions across the Lifespan and Risk of Stroke: A Life-Course Epidemiological Analysis of 22,847 Adult Americans. International Journal of Stroke, 2013;8:50-55, PMID:23231424. PubMed

Longjian Liu, Jennifer A Nettleton, Alain G Bertoni, David A Bluemke, João A Lima, and Moyses Szklo: Dietary pattern, the metabolic syndrome, and left ventricular mass and systolic function: the Multi-Ethnic Study of Atherosclerosis. American Journal of Clinical Nutrition. 2009 Aug;90(2):362-8. PMID: 19515735. PubMed

Courses

PBHL 639:  Cardiovascular Disease Epidemiology and Prevention

PBHL 656:  Pharmacoepidemiology

PBHL 634:  Epidemiology for Public Health Practice

PBHL 822:  Epidemiology of Reproductive Health and Cardiovascular Disease (PhD student independent study)