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Longjian Liu, MD, PhD, MSc, FAHA

Associate Professor of Epidemiology and Biostatistics, and Former Interim Chair
Epidemiology and Biostatistics
267.359.6049
LL85@drexel.edu
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Degrees

MD, Shanxi Medical University; MSc in Epidemiology, The University of London School of Hygiene and Tropical Medicine; PhD in Epidemiology, The University of Hong Kong; and MD Postdoctoral Fellowship in Geriatrics, The University of Arkansas for Medical Sciences.

Bio

Dr. Longjian Liu is a tenured professor of Epidemiology & Biostatistics, and the former Interim Chair of the Department of Environmental and Occupational Health at Drexel University Dornsife School of Public Health. He is also an adjunct professor of medicine at Drexel University College of Medicine. Prior to joining Drexel, Dr. Liu received training and have teaching and research experience in medicine, epidemiology and biostatistics in leading universities of China (Shanxi Med Univ., Chongqing Med Univ., and Beijing Med Univ.), of the United Kingdom (LSHTM), Japan (SUMS, and Kyoto Univ.), and the United States (UAMS). Dr. Liu has been a Fellow of the American Heart Association (FAHA) since 2008.

Dr. Liu teaches Cardiovascular Disease Epidemiology and Prevention (PBHL 639), Pharmacoepidemiology (PBHL 656), Epidemiology for Public Health Practice (PBHL 634). He also led to develop and taught online courses, entitled “Certificate in Epidemiology and Biostatistics Principles and Methods for Public Health in the 21st Century” (PBHL 701, 702). Dr. Liu coauthored the chapter, Cardiovascular Disease Epidemiology in the APHA-published textbook of Chronic Disease Epidemiology and Control (3rd Ed., 2010, and 4th Ed., 2016).  

Dr. Liu’s research has focused on epidemiology of cardiovascular disease, diabetes mellitus, aging-related neurodegenerative disorders, and biomarkers, drug resistance, and environmental - drug interactions on disease control and prevention. Dr. Liu has extensive research experience in working with several regional, national and international studies. He has more than 70 articles published in peer-reviewed national and international journals that reach a total Impact Factor score more than 170. The overarching goal of his research is to translate research findings to disease and risk factor control and prevention

Four integrated themes are included in his research activities:

(1). Environmental Risk Factors of Cardiovascular Disease and Urban Health: Dr. Liu has involved in the World Health Organization (WHO) - Cardiovascular Disease and Alimentary Comparison (WHO-CARDIAC) Study, the WHO – World Health Surveys (WHS), and the Study on Global Ageing and Adult Health (SAGE). The goal of these studies is to examine environmental risk factors (built environmental, air pollution, healthcare system) and lifestyle-related risk factors for hypertension, heart disease, stroke and diabetes mellitus across nations. Dr. Liu is the Principal Investigator of Drexel (US) - SARI (China) research and Education project on Climate Change, Energy, Low-Carbon, and Urban Health Technology. 

(2). Biomarkers, Drug Resistance and Arterial Aging: Studies of determinants of hypertension, heart disease, stroke, diabetes mellitus, and the consequence of cognitive and neurodegenerative disorders in aging population. Dr. Liu is the Principal Investigator for the study of environmental (E) and drugs, and E - drugs interaction on the risk of heart disease in patients with diabetes mellitus and/or Chronic Kidney Disease. 

(3). Micronutrients, Fatty Acids and Healthy Aging: Studies of the impacts of micronutrients, fatty acids, oxidative stress and inflammation on metabolic disorders, arthrosclerosis and neurodegenerative disorders.

(4). Application of Advanced Analytic Techniques and Mining “Big Data”: Multivariate analysis, mining “big data”, and biological network analysis. Real-time disease risk surveillance and statistical predictive modeling using data from multiple hospitals’ electronic health records, such as Nationwide Inpatient Sample, and National Hospital Discharge Surveys, data from regional, national and international population-based health surveys.

Research Interests

  • Cardiovascular Disease
  • Diabetes
  • Environmental Exposures
  • Global health or International health
  • Health Disparities
  • Infectious Disease
  • Neurodevelopment and Neurologic disorders
  • Nutrition
  • Spatial Analysis or  GIS
  • Urban Health
  • Pharmacoepidemiology
  • Air Quality and Urban Health in China
  • Health Failure Epidemiology

Publications

Longjian Liu, Barbara Simon, Jinggaofu Shi, Arshpreet Kaur Mallhi, Howard J Eisen: Impact of diabetes mellitus on risk of cardiovascular disease and all-cause mortality: Evidence on health outcomes and antidiabetic treatment in United States adults. World J Diabetes. 2016 Oct 15;7(18):449-461. PMID: 27795819. PubMed.

Longjian Liu, Xuan Yang, Yong Long, Arshpreet Kaur Mallhi, Kathan Mehta, Erol Veznedaroglu, Xiaoyan Yin: Changes in the prevalence of hospitalization and comorbidity in US adults with stroke: A three decade cross-sectional and birth cohort analysis. International Journal of Stroke, PrePub Online July 13, 2016. PMID: 27412189. PubMed.

Longjian Liu, Xuan Yang, Hui Liu, Mingquan Wang, Seth Welles, Shannon Márquez, Arthur Frank, Charles N Haas: Spatial–Temporal Analysis of Air Pollution, Climate Change, and Total Mortality in 120 Cities of China, 2012–2013. Frontiers in Public Health, 2016 Jul 18;4:143. PMID: 27486572. PubMed.

Jing Sun, Pooja Rangan, Srinidhi Subraya Bhat, and Longjian Liu: A Meta-Analysis of the Association between Helicobacter Pylori Infection and Risk of Coronary Heart Disease from Published Prospective Studies. Helicobacter, 2016 Feb:21(1):11-23. PMID: 25997465. PubMed

Longjian Liu and Ana E. Núñez: Multilevel and Urban Health Modeling of Risk Factors for Diabetes Mellitus: A New Insight to Public Health and Preventive Medicine. Advances in Preventive Medicine, 2014, 1-7. PMID 25431678. PubMed

Longjian Liu and Howard J Eisen: Epidemiology of heart failure and scope of the problem. Cardiology Clinics, 2014, 32(1):1-8. PMID: 24286574. PubMed

Longjian Liu, Katsuyuki Miura, Akira Fujiyoshi, Aya Kadota, Naoko Miyagawa, Yasuyuki Nakamura, Takayoshi Ohkubo, Akira Okayama, Tomonori Okamura, Hirotsugu Ueshima: Impact of Metabolic Syndrome on the Risk of Cardiovascular Disease Mortality in the United States and in Japan. American Journal of Cardiology, 2014, 113(1):84-89. PMID: 24169008. PubMed

Longjian Liu, Yuan An, Ming Chen, Zuolu Liu, Xiaohua Hu, Edgar Chou and Howard J. Eisen: Trends in the prevalence of hospitalization attributable to hypertensive diseases among United States adults aged 35 and older from 1980 to 2007. American Journal of Cardiology 2013;112:694-699, PMID: 23726180. PubMed

Yong Long, Edward J. Gracely, Craig J. Newschaffer and Longjian Liu: Analysis of the prevalence of cardiovascular disease and associated risk factors for European-American and African-American populations in the state of Pennsylvania 2005-2009. American J Cardiology. 2013;111:68-72. PMID: 23040600. PubMed

Longjian Liu, Jennifer A Nettleton, Alain G Bertoni, David A Bluemke, João A Lima, and Moyses Szklo: Dietary pattern, the metabolic syndrome, and left ventricular mass and systolic function: the Multi-Ethnic Study of Atherosclerosis. American Journal of Clinical Nutrition. 2009 Aug;90(2):362-8. PMID: 19515735. PubMed

For a complete listing visit PubMed

Courses

Advisor for Master degree and PhD students

PBHL 639: Cardiovascular Disease Epidemiology and Prevention

PBHL 656: Pharmacoepidemiology

PBHL 634: Epidemiology for Public Health Practice

PBHL 822: Epidemiology of Reproductive Health and Cardiovascular Disease (PhD independent study)