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Brian Lee, PhD

Associate Professor

Phone: 267.359.6052
College: School of Public Health
Program: Epidemiology and Biostatistics

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AB, Biological Anthropology, Harvard College; MHS, Epidemiology, Johns Hopkins University; PhD, Epidemiology, Johns Hopkins University


Dr. Lee received his PhD and MHS degrees in Epidemiology from The Johns Hopkins University, and graduated Cum laude with an AB in Biological Anthropology from Harvard College. His research interests include the epidemiology of neurological development, maintenance and decline.  Current topics include prenatal environmental exposures and autism risk; neighborhoods and psychosocial "stress" in the cognitive decline of older adults; lead toxicity and white matter health; gene-environment interaction; maternal antibody exposure in utero and fetal outcomes.  In addition to his etiological research, Dr. Lee is interested in epidemiological methods including causal inference methodology, data mining and machine learning algorithms, and automated data extraction techniques for structured and unstructured data.

Research Interests

  • Exposure assessment
  • Environmental determinants of autism spectrum disorders
  • E-Epidemiology
  • Machine learning
  • Perinatal epidemiology
  • Environmental exposures
  • Experimental design/research methods
  • Epidemiology of autism spectrum disorders
  • Environmental determinants of health
  • Epidemiology
  • Biomarkers
  • Child and maternal health
  • Gene-environment interaction
  • Neurological disorders


Rai D, Lee BK, Dalman C, Golding J, Lewis G, Magnusson C. Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study. BMJ 2013;346:f2059.

Nguyen CT, Gracely EJ, Lee BK. Serum Folate but Not Vitamin B-12 Concentrations Are Positively Associated with Cognitive Test Scores in Children Aged 6-16 Years. The Journal of Nutrition. Feb 6 2013.

Idring S, Rai D, Dal H, Dalman C, Sturm H, Zander E, Lee BK, Serlachius E, Magnusson C. Autism spectrum disorders in the Stockholm Youth Cohort: design, prevalence, and validity. PLoS ONE 7(7): e41280. 

Lee BK, Gardner RM, Dal H, Svensson A, Galanti MR, Rai D, Dalman C, Magnusson C. Brief report: maternal smoking during pregnancy and offspring autism spectrum disorders. Journal of Autism and Developmental Disorders, 2011. 

Lee BK, Glass TA, James BD, Bandeen-Roche K, Schwartz BS. Neighborhood psychosocial environment, apolipoprotein E genotype, and cognitive function in older adults. Archives of General Psychiatry.2011;68(3):314-321.

Lee BK. Epidemiologic Research and Web 2.0-the User-driven WebEpidemiology 2010. Nov;21(6):760-763.

Lee BK, Lessler J, Stuart EA. Improving propensity score weighting using machine learning. Statistics in Medicine 2010; 29(3):337-46.