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Biochemistry Research

DNA molecules. Photograph by Charles Clegg.

Researchers in biochemistry investigate the metabolic processes affecting nutrients and cellular components. This includes the biosynthesis, processing, intracellular trafficking and disposal of biomolecules such as proteins and lipids. It also includes studies on the maintenance of intracellular homeostasis involving bioenergetics and redox status. Major foci are the regulatory mechanisms of homeostasis and adaptation to changes of the microenvironment such as nutrient depletion or disease conditions; signaling pathways in physiological and pathological conditions; and pathological accumulation of macromolecules or metabolites from enzyme defects. The long-term goal of much of this work in our department is to identify molecular targets for the prevention and treatment of human disease. Additional research interests include studies of drug disposal, pharmacokinetics, and mechanisms of drug resistance. Biology faculty in this research area collaborate with investigators in the Sydney Kimmel Cancer Center, pharmaceutical industries such as GlaxoSmithKline, and other institutes worldwide.

Faculty conducting research in Biochemistry

Contact Specialization
Michael Akins
Assistant Professor
PISB 319
mra69@drexel.edu
Experience-dependent plasticity in the mammalian nervous system; post-transcriptional regulation of gene expression in neurons
Dr. Joseph Bentz
Professor Emeritus
PISB 416
bentzj@drexel.edu
Biophysics of Cell Membrane Function - Membrane Transport by Multidrug Resistance Proteins, chanisms of Membrane Fusion, Peptide/Protein-Membrane Interactions
Tali Gidalevitz
Assistant Professor
PISB 418
Tali.gidalevitz@drexel.edu
Nianli Sang, M.B., Ph.D.
Co-Director of the Cell Imaging Center; Associate Professor
PISB 417
nianli.sang@drexel.edu
Molecular, Cellular and Biochemical Bases of Major Human Diseases
Aleister Saunders, PhD
Senior Vice Provost for Research; Professor
104 Left Bank
Aleister.Saunders@drexel.edu
Biochemistry, Genetics, Molecular/Cellular Biology
Elias Spiliotis, Ph.D.
Associate Professor; Director of the Biology Graduate Program; Director of the Cell Imaging Center
PISB 423
ets33@drexel.edu
Cell biology, cytoskeleton (microtubules, actin, septins), neuronal and epithelial morphogenesis, spatial regulation of intracellular transport, cell motility and cell division.