Auchincloss' research focuses on social and environmental determinants of chronic health conditions. Her work has examined restaurant nutritional labeling and its impact on healthier food choices; spatial risk factors within residential environments that influence health behaviors related to obesity and type 2 diabetes; the application of novel complex systems modeling that can be used to examine spatial and socio-economic patterning of health behaviors/outcomes; air pollution epidemiology including the contribution of atmospheric conditions (temperature and barometric pressure) and vehicular traffic to air pollution in relation to cardiovascular-related endpoints.

Lee's research interests include the epidemiology of neurological development, maintenance and decline.  Current topics include prenatal environmental exposures and autism risk; neighborhoods and psychosocial "stress" in the cognitive decline of older adults; lead toxicity and white matter health; gene-environment interaction; maternal antibody exposure in utero and fetal outcomes.