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Events Calendar

  • Axon Initial Segment in Mammalian Brain Function / Nanomaterials for Inducing Antigen-Specific IT

    Wednesday, October 21, 2020

    9:00 AM-10:30 AM

    Remote Webinar

    • Undergraduate Students
    • Graduate Students
    • Faculty
    • Staff

    BIOMED Dual Seminar

    Title Seminar #1:
    Roles of the Axon Initial Segment in Mammalian Brain Function Under Physiological and Pathological Conditions
     
    Speaker:
    Dr. Shuijin He
    Assistant Professor
    School of Life Science and Technology
    ShanghaiTech University

    Details:
    A neuron has specialized structures that consist of the dendrite, the axon and the axon initial segment (AIS). The AIS is the site that connects the soma and the distal axon, and responsible for generating an action potential in a neuron by integration of all information that the dendrite receives from other neurons. Then the action potential propagates along the axon to the axonal terminals, which make connections with the dendrite of other neurons by releasing neurotransmitters. Recently, super-resolution imaging uncovered a periodic arrangement of AIS cytoskeletal proteins, exhibiting rings spaced approximately 190 nm apart. During normal development, the AIS undergoes dynamic changes in the length and location in response to synaptic inputs. This activity-dependent AIS plasticity is crucial for shaping neural networks of the nervous system. Likewise, the AIS cytoskeleton undergoes rapid and irreversible disruption prior to cell death after injury, and loss of AIS integrity can produce profound neurological effects on the nervous system. In this presentation, I will talk about how AIS diameter is regulated in the mammalian neocortex and what roles AIS diameter likely plays in brain functions under physiological conditions. Then I will further discuss the mechanism for an ischemia-induced alteration in AIS integrity.

    Biosketch:
    Shuijin He, PhD, is an assistant professor in the School of Life Science and Technology at ShanghaiTech University. Dr. He received a BS in biochemistry from the Lanzhou University in 2000, an MS in biophysics from the University of Science and Technology of China in 2003, and a PhD in neuroscience from Uniformed Services University in the USA in 2010. Following a research fellowship at the Memorial Sloan Kettering Cancer Center in New York City, Dr. He established his lab at ShanghaiTech University in 2015. His lab is interested in elucidating how neural circuits precisely assemble during development at both the molecular and cellular levels using electrophysiological methods, combined with super-resolution imaging, single cell sequencing, and genetic tools.

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    Title Seminar #2:
    Nanomaterials for Inducing Antigen-Specific Immune Tolerance

    Speaker:
    Hao Cheng, PhD
    Associate Professor,
    Department of Materials Science and Engineering (MSE)
    Drexel University

    Details:
    Induction of antigen-specific immune tolerance, which reduces autoreactive immune cells and generates antigen-specific regulatory T cells in patients, is a promising strategy for curing autoimmune diseases. Systemic administration of poly(lactic-co-glycolic acid) (PLGA) nanoparticles with auto-antigen peptides have been demonstrated to induce antigen-specific immune tolerance in experimental autoimmune encephalitis (EAE), a murine model of multiple sclerosis. However, the same nanoparticles failed to alleviate the disease after subcutaneous (s.c.) injection. S.c. administration has the potential advantage in spatiotemporally modulating immune cells in a well-controlled microenvironment. It is unknown what material properties are necessary for inducing tolerance via s.c. administration. Addressing this question will advance nanomaterial design for immune tolerance. We have found PLGA nanoparticles induced inflammatory responses after s.c. injection in mice. After reducing the complement activation of nanoparticles, we show that nanoparticles encapsulating MOG peptide can induce antigen-specific immune tolerance in EAE after disease onset via s.c. administration of the nanomaterials.

    Biosketch:
    Hao Cheng, PhD, is an associate professor in the Department of Materials Science and Engineering (MSE) at Drexel University. He received his BE and MS degrees in Chemical Engineering from Tsinghua University in 1999 and 2001, respectively. Dr. Cheng completed his PhD in Materials Science and Engineering at Northwestern University in 2005. Prior to joining Drexel University in 2012, he was a postdoctoral associate at Northwestern University and MIT. Dr. Cheng's laboratory focuses on cell membrane-derived hydrogels, long circulating nanoparticles, and biomaterials/biological materials for inducing antigen-specific immune tolerance. As a corresponding or co-corresponding author, Dr. Cheng has published in journals, such as ACS Nano, Advanced Materials, Nano Letters, Nature Communications, and Advanced Drug Delivery Reviews. He was a recipient of the inaugural Nano Research Young Innovators Award in Nanobiotechnology in 2018.

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  • Through June 2021: Seat at the Table Exhibition

    Wednesday, October 21, 2020

    10:00 AM-6:00 PM

    Virtual until January Kimmel Center for the Performing Arts 300 S. Broad Street Philadelphia, PA 19102

    • Everyone

    Women 100, a program of Vision 2020, is hosting "Seat at the Table," an exhibition that commemorates the 19th Amendment — establishing women’s right to vote — and asks 100 years later, “Where are we now?” Visitors will experience the current status of gender equality in the U.S. through 3D infographic furniture.

    "Seat at the Table" is temporarily closed. The multimedia segment of the exhibition is available at women100.org/seatatthetable.

    When the Kimmel Center reopens, "Seat at the Table" will be presented in the lobby daily from 10 a.m. to 6 p.m., through June 2021.

    Learn more about Seat at the Table

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  • Ten at 10: Water-Cooler Wednesdays (1 Wellness Incentive Point Per Day)*

    Wednesday, October 21, 2020

    10:00 AM-10:10 AM

    Online, please visit our website for more information: https://drexel.edu/hr/benefits/a-healthier-u/ten-at-10/

    • Faculty
    • Staff
    Wednesdays are "Water-Cooler Wednesdays." Visit the Ten at 10 Website to connect with resources that can help you take advantage of a simple but powerful body-mind reset. Please visit our website and click on "Water-Cooler Wednesdays" to learn more.
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  • Virtual: Microbiology & Immunology Seminar

    Wednesday, October 21, 2020

    12:00 PM-1:00 PM

    Online Event

    • Graduate Students
    • Faculty
    • Staff

    Please note: This event is online only.

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  • “Doing IT Right”

    Wednesday, October 21, 2020

    12:00 PM-1:00 PM

    via Zoom

    • Graduate Students
    • Faculty
    • Staff

     Presentation Time: 12pm -1pm EST

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  • Virtual: Neurobiology & Anatomy Seminar

    Wednesday, October 21, 2020

    12:00 PM-1:00 PM

    Online Event

    • Graduate Students
    • Faculty
    • Staff

    Please note: This event is online only.

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  • Pathways to Dual Teacher Certification

    Wednesday, October 21, 2020

    12:00 PM-1:00 PM

    This event will be held exclusively online. Please register to receive log-in information.

    • Everyone
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  • Stretch and Restore (15 Wellness Points)*

    Wednesday, October 21, 2020

    12:00 PM-12:45 PM

    Zoom; registration in Career Pathway is required; the link to join will be sent by Career Pathway after you register

    • Faculty
    • Staff

    This gentle yoga and breathing class will be a hands-on movement class. Our Wellness Administrator Monica Fauble, Licensed Acupuncturist & Yoga Teacher, will lead you through a series of stretches and breathing practices that can be done at home or in your office.

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  • Grants for Research in Germany & Switzerland

    Wednesday, October 21, 2020

    12:00 PM-1:00 PM

    Online (register in advance).

    • Undergraduate Students
    • Graduate Students
    DAAD RISE and RISE Professional offer 3-month funded summer research internships in Germany for students in biology, chemistry, physics, earth sciences, engineering, and related fields. ThinkSwiss offers funding for 2-3 month research stays in Switzerland for any field. Both graduate and undergraduate students are eligible and US citizenship is not required. This session will cover program basics and how to apply.
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  • Motherhood Across Borders: Mexican Immigrants and their Children in Mexico and in New York City

    Wednesday, October 21, 2020

    12:00 PM-1:00 PM

    This event will be held exclusively online. Please register to receive log-in information.

    • Everyone
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