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Medical Science Research Experience

About the Research Experience

What sets the Master of Science in Medical Science program apart from most other post-baccalaureate programs is the research experience; this is the centerpiece of the Year Two curriculum and indeed, the entire Medical Science program. The research experience during Year Two of the Medical Science program is designed to be rigorous, intense, productive, transformative and engaging.

During the summer of Year One, Medical Science students develop independent research proposals with a chosen faculty mentor. Research proposals are carefully reviewed by the Medical Science Research Oversight Committee. The Research Oversight Committee comprises the Medical Science program director and premier faculty researchers invited from the Graduate School of Biomedical Sciences and Professional Studies. Each student proposal is carefully reviewed and either approved or returned with comments. Once approved, Medical Science students engage in a minimum of 18 hours of research a week, though most put in much more time.

Just as the research experience sets the Medical Science program apart, it is a transformative experience that sets Medical Science students apart from other applicants to medical school. The research experience allows students to develop real expertise, both technically and in their field of interest. They learn how to formulate and test scientific questions, critically analyze their data and present their findings in a variety of formats. Equally important, students learn professionalism and are mentored by leading scientists. The professional relationships forged during the Medical Science research experience can be the foundation of students' professional network and last the entirety of their careers.

Past Research Projects

Most Medical Science students work in cutting-edge research and make significant contributions to the research enterprise. Titles of past Medical Science research projects include:

Hepatitis B Virus X-interacting Protein (HBXIP) Mediated Inhibition of HBV Replication Through mTORC1
Student: John Allsop, MMS 2019
PI: Michael Bouchard
Site: Drexel University College of Medicine

Exercise Effects on Repetitive Mild Traumatic Brain Injured (r-mTBI) Male Mice
Student: Dominic Campion, MMS 2019
PI: Ramesh Raghupathi
Site: Drexel University College of Medicine

Characterization of the Dorsal Horn in a Spinal Cord Injury Model of Neuropathic Pain
Student: Michael Demarco, MMS 2019
PI: Angelo Lepore
Site: Jefferson Medical College

Targeting CARs to the TET2 Locus with CRISPR/Cas9-based Genome Editing
Student: Steven Feins, MMS 2019
PI: Joseph A. Fraietta
Site: University of Pennsylvania

Infant Medical Attributes on Parental Psychosocial Functioning After Leaving the NICU
Student: Austin LaRocca, MMS 2019
PI: Pam Geller
Site: Drexel College of Arts and Sciences

Plasticity of Rhythmic and Modulatory Respiratory Axons Drives Diaphragm Recovery After Focal BDNF Upregulation in Rats
Student: Katherine Locke, MMS 2019
PI: Angelo Lepore
Site: Jefferson Medical College

Interplay of AMPK Signaling and Autophagy in Hepatitis B Virus Replication
Student: Dara Tolchin, MMS 2019
PI: Michael Bouchard
Site: Drexel University College of Medicine

Effects of Pulsed Magnetic Field on Macrophage Marker Expression and Protein Secretion
Student: Hieu Vo, MMS 2019
PI: Boris Polyak
Site: Department of Surgery, Drexel University College of Medicine

2018

  • Hepatitis B Virus X-Interacting Protein in the Context of Hepatitis B Virus Replication
    Student: Ahsun Bajwa, MMS 2018
    PI: Michael Bouchard, PhD
    Department of Biochemistry & Molecular Biology, Drexel University College of Medicine
  • Focal BDNF Overexpression Promotes Recovery of Respiratory Function After Cervical Spinal Cord Injury in Adult Rats
    Student: Michael A. Brinton, MMS 2018
    PI: Angelo LePore, PhD
    Department of Neuroscience, Jefferson University Medical College
  • Development of a Novel Microfabricated 3D Liver Model
    Student: Eric Haljasmaa, MMS 2018
    PI: Michael Bouchard, PhD
    Department of Biochemistry & Molecular Biology, Drexel University College of Medicine
  • Effect of Exercise on Behavioral Impairments in Female C57BL/6J Mice Following Repetitive mild-Traumatic Brain Injury
    Student: Mohibur Rahman, MMS 2018
    PI: Ramesh Raghupathi, PhD
    Department of Neurobiology & Anatomy, Drexel University College of Medicine
  • Investigation of the Possibility of Septin Hexamer & Octamer Co-polymerization
    Student: Robert Kelley, MMS 2018
    PI: Shae Padrick, PhD
    Department of Biochemistry & Molecular Biology, Drexel University
  • An Investigation of the Mechanism of Exercise Modulated Chloride Homeostasis and Dendritic Plasticity after SCI in Rattus Norvegicus.
    Student: V.Vigneswaran, MMS 2018
    PI: Marie-Pascale Côté, PhD
    Department of Neurobiology & Anatomy, Drexel University College of Medicine
  • Define the Role of the Bone Stroma and Tumor Heterogeneity in the Prostate Cancer Metastatic Niche
    Student: Marissa Matto, MMS 2018
    PI: Alessandro Fatatis, MD, PhD
    Department of Pharmacology & Physiology, Drexel University College of Medicine
  • Positive Allosteric Modulation of Glutamate Transporter EAAT2 for Stroke: In Vitro Studies on Primary Neuronal Cultures
    Student: Srawasti Sarker, MMS 2018
    PI: Andreia C. K. Mortensen, PhD
    Department of Pharmacology & Physiology, Drexel University College of Medicine

2017

  • Designing a multicolor flow panel for the analysis of inhibitory receptor expression on Human T-cells
    Brenndan Crumley, 2017
  • The Impact of PTEN Antagonist Peptides on rVRG Axonal Regeneration and Restoration of Diaphragm Function Following Spinal Cord Injury
    Cole Block 2017
  • HBx-mediated calcium signaling and its effect on Akt and the development of HBV-associated HCC
    Conor O’Meara, 2017
  • Juvenile mGluR2/3 agonist LY379268 treatment prevents adult behavioral deficits in a developmental rat model of schizophrenia
    Genie Han, 2017
  • Differential prevalence of CYP2R1 mutations across populations reveals an adaptive mechanism and pathway selection to maintain serum 25-hydroxyvitamin D
    Ilana Caplan, 2017
  • Targeting Spinal Dopaminergic Regulation to Improve Micturition Recovery After Spinal Cord Injury in Rats
    Jemin Ahn, 2017
  • Impact of parental report of infant health severity on parental stress levels
    Jennifer Morris, 2017
  • Using 3D Printing to Identify Residual Transverse Arch obstruction in Aortic Coarctation Correction
    Kevin Gralewski, 2017
  • Effect of Exercise on Depression-like Behavior and Facial Allodynia Following Repetitive Mild Traumatic Brain Injury
    Melanie Zemel, 2017
  • Effects on Spatial Learning and Anxiety-like Behavior in C57BL/6J Mice after Repetitive Mild-Traumatic Brain Injuries
    Michael Branham, 2017
  • Cortical expression of diacylglycerol lipase-α increases in DSP-4 treated rats
    Michael Nitikman, 2017
  • Reconstitution Of GAP43 on Synthetic Bilayer Membranes
    Olufela Koleoso, 2017
  • Neuroprotective effects of novel positive allosteric modulators of glutamate transport
    Rebisi Owhonda, 2017

2016

  • "Exploring the Impact of GSK-3β Ablation on Cognitive Function and Structural Plasticity of the PFC"
    Rita Akumo, 2016
  • "Does Central Venous Pressure Correlate With Physician Implementation of Fluid Resuscitation in Hypotensive Patients?"
    Todd Belok, 2016
  • "Effects of Radiation on Cell Functions in Glioma Cancer Stem Cells"
    Puneet Butter, 2016
  • "Effects of Pre-Injury Exercise on Behavioral Outcomes in Single Mild Traumatic Brain Injury in Adolescent Mice"
    Archana Chandrashekar, 2016
  • "Novel Dopamine Transporter Modulator in a Behavioral Model of Addiction in Planarians"
    Annie Chang, 2016
  • "Identifying Predictors of Retention and Abstinence Among Women in Outpatient Substance Abuse Treatment"
    W. Chase Hamilton, 2016
  • "Imaging and Appendicitis: Limiting Radiation Exposure in Children with Abdominal Pain. Do we really need another CT scan?"
    Mack Hardaker, 2016
  • "Supraphysiological O-GlcNAcylation Increases Differentiated ARPE-19 Cell Permeability"
    Jennifer Huang, 2016
  • "Modulation of Dopamine Transporter Using Novel Compounds to Decrease Its Affinity for Cocaine"
    Poojitha Kakulavaram, 2016
  • "A New Genetic Mouse Model for Hereditary Spastic Paraplegia 4 Expressing Mutant Human SPAST"
    Evan Kolesnick, 2016
  • "NICU Infant Health Severity and Family Functioning"
    Catherine M. Madden, 2016
  • "Investigating Cytoprotective Mechanisms Against Alcohol Exposure in Human Esophageal Cells"
    Alec Maggi, 2016
  • "Investigation of Motivation Interviewing and Prevention Consults to Achieve Cardiovascular Targets (IMPACT) Study"
    Farah Noorani, 2016
  • "Transport Domain-Unlocking Results in Augmented Uptake Rate in EAAT2 Glutamate Transporter"
    Avkash Patel, 2016
  • "Norepinephrine Transporter: A Receptor Wherein Expression Is Affected by the Molecular Chaperone Hsc70"
    Eugene Pok, 2016
  • "Cell-Specific Viral Vector Induced Regeneration of Respiratory Circuitry Following Cervical Spinal Cord Injury"
    Laura Strojny, 2016
  • "Role of BPIFB1 on Hepatitis B Virus Replication"
    Sowmya Swamy, 2016
  • "The Relationship Between Depression, Infertility Related Distress, and Religiosity in Infertile Muslim Women Living in the West"
    Mirzya Syed, 2016
  • "Investigating the Role of ALDH2 in Response to Alcohol Exposure"
    Nhi Tran, 2016

 
Research Mentors

We are honored to have truly gifted scientists serving as Medical Science research mentors. Past and current research mentors include:

Drexel University College of Medicine

Michael Bouchard, PhD*
Professor, Department of Biochemistry & Molecular Biology; Director, Division of Biomedical Science Programs

Jane Azizkhan-Clifford, PhD
Professor and Chair, Department of Biochemistry & Molecular Biology; Associate Dean for Medical Student Research

Simon Cocklin, PhD*
Assistant Professor, Department of Biochemistry & Molecular Biology

Marie-Pascale Côté, PhD
Assistant Professor, Department of Neurobiology & Anatomy

Alessandro Fatatis, MD, PhD
Professor, Department of Pharmacology & Physiology

Wen-Jun Gao, PhD
Professor, Department of Neurobiology & Anatomy

Olimpia Meucci, MD, PhD
Professor and Chair, Department of Pharmacology & Physiology

Andréia C.K. Mortensen, PhD
Research Assistant Professor, Department of Pharmacology & Physiology

Ole Mortensen, PhD
Associate Professor, Department of Pharmacology & Physiology

Eishi Noguchi, PhD
Associate Professor, Department of Biochemistry & Molecular Biology; Director, Graduate Program in Molecular & Cellular Biology & Genetics

Shae Padrick, PhD
Assistant Professor, Department of Biochemistry & Molecular Biology

Boris Polyak, PhD
Associte Professor, Departments of Surgery, and Pharmacology & Physiology

Ramesh Raghupathi, PhD
Professor, Department of Neurobiology & Anatomy

Barbara Schindler, MD
Professor, Departments of Psychiatry and Pediatrics; Vice Dean Emerita, Educational & Academic Affairs

Brian Wigdahl, PhD
Professor and Chair, Department of Microbiology & Immunology; Director, Institute for Molecular Medicine and Infectious Disease

*Current or former Research Oversight Committee member

Drexel University College of Arts and Sciences

Pamela Geller, PhD
Associate Professor, Ob/Gyn and Public Health, Department of Psychology

Jefferson Medical College

Angelo Lepore, PhD
Assistant Professor, Department of Neuroscience

Hospital of the University of Pennsylvania / Children's Hospital of Philadelphia

University of Pennsylvania

Pavan Atluri, MD
Assistant Professor of Surgery, Department of Cardiovascular Surgery

Yi Fan, MD, PhD
Assistant Professor, Department of Radiation Oncology

Joseph A. Fraietta, PhD
Assistant Professor, Department of Microbiology; Director, Solid Tumor Immunotherapy Laboratory, Center for Advanced Cellular Therapeutics

Reynold A. Panettieri Jr., MD
Robert L. Mayock and David A. Cooper Professor of Medicine; Director, Airways Biology Initiative

Pink gloved hands with dropper, medical science graduate student at Drexel University College of Medicine.

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