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Center for Systems & Behavioral Neurobiology

Systems and Behavioral Neurobiology

The Center for Systems & Behavioral Neurobiology at Drexel’s Department of Neurobiology and Anatomy is dedicated to investigating the molecular, cellular, network, and behavioral mechanisms of sensory information processing, learning and memory, attention, emotion, locomotion, feeding, motivation and the neuropsychiatric disorders associated with these processes.

Members of the Center include a diverse group of neuroscientists who interrogate the neural mechanisms underlying behavior by employing an array of techniques to examine the processes by which the brain orchestrates behavior and how dysregulation of these processes leads to psychiatric disorders.

The collaborative nature of our members has led to extensive scientific interactions among faculty, students, and post-doctoral fellows within the Center, the Department, the University and beyond. Through an open exchange of ideas and knowledge, the Center aims to uncover the neural processes underlying adaptive and maladaptive behavior, which will pave the way for treating neurological and psychiatric disorders.

RESEARCH AREAS

  • Anxiety, stress, depression, PTSD
  • Autism
  • Binge eating
  • Executive function
  • Learning and memory
  • Locomotion and neural networks
  • Pain
  • Parkinson’s Disease
  • Social behavior
  • Schizophrenia
  • Sleep and arousal
  • Spinal cord injury
  • Substance abuse
  • Traumatic brain injury

METHODOLOGIES

  • DREADDs
  • Electrophysiology
  • Fiber Photometry
  • Gene, protein, & peptide assessment
  • Microendoscopy & calcium imaging
  • Molecular profiling
  • Neurochemistry
  • Optogenetics
  • Sophisticated behavioral assessment
  • Transgenic models

SHARED FACILITIES

  • Rat Behavioral Testing Rooms: 3 chamber test, 5-choice serial reaction, acoustic startle, activity chambers, conditioned place preference, elevated plus maze, forced swim, hole board, light-dark box, locomotor activity, Morris water maze, novel object recognition, open field, operant chambers, T-maze
  • Slice Electrophysiology
  • Fast Scan Cyclic Voltammetry
  • Fiber Photometry
  • Fluid Percussion Injury
  • High-Performance Liquid Chromatography

 

  • Mouse Behavioral Testing Rooms: 3 chamber test, attentional set shifting, conditioned place preference, cross maze, elevated plus maze, fear conditioning, home cage behavior, light-dark box, locomotor activity, novel object recognition, optogenetics, T-maze
  • Predator Odor Exposure
  • Quantitative Real-Time PCR
  • RNAScope
  • Sleep Physiology
  • Surgical set-ups

MEET OUR FACULTY

You can learn more about our research and current projects by visiting our individual faculty lab pages.

MEET OUR STUDENTS

España Lab
Kyle Samson
Phillip Clark

Barker Lab
Christina Curran-Alfaro
Katie Bryant

Dougherty Lab
Jenna McGrath
Shayna Singh
Nicholas Stachowski

Raghupathi Lab
Joya Maser
Pryscilla Santos Acevedo
Taylor McCorkle

Barson Lab
Brody Carpenter
Breanne Pirino
Genevieve Curtis

Detloff Lab
Jonathan Richards
John Walker

Gao Lab
Abby Keith
Nancy Mack

Wang Lab
Arron Hall
Ashley Opalka
Candace Rizzi-Wise

 
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