New Drug Class Causes Malaria to Burst
December 1, 2014
An international research team led by Akhil B. Vaidya, PhD, professor in the Department of Microbiology & Immunology and director of the Center for Molecular Parasitology at Drexel University College of Medicine, has discovered a new class of drug compounds that could lead to potent new treatments in the battle against malaria. The results from preclinical studies are set for online publication in the November 25 edition of Nature Communications. The compounds affect the malaria parasites' ability to maintain adequate levels of sodium within their cells, leading to excessive water intake, which causes the parasites to burst.